(R)-cis-5ξ-Methyl Atracurium Dibesylate

N° de SZ CAT:	SZ-A021034
Número CAS	1193104-82-3
Mol.F.	C54H74N2O12 : 2(C6H5O3S)
Peso Molecular	943.2 : 2(157.2)
Status de Fatura	In Stock
Rel. CAS No	1193104-81-2 (free base)

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Nome Químico: (1R,1'R,2R,2'R)-2,2'-((Hexane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) Dibenzenesulfonate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=[S]([O-])(C1=CC=CC=C1)=O.C[N@@+]2(CCC(OC(C)CCCCOC(CC[N@+]([C@@H]3CC4=CC(OC)=C(OC)C=C4)(CCC5=CC(OC)=C(OC)C=C35)C)=O)=O)[C@@H](C6=CC(OC)=C(OC)C=C6CC2)CC7=CC(OC)=C(OC)C=C7.O=[S]([O-])(C8=CC=CC=C8)=O

Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection
Agata Błazewicz, Zbigniew Fijałeka,b, Małgorzata Warowna-Grzeskiewicz ,Magdalena Jadach
Journal of Chromatography A, 1217 (2010) 1266–1272

Directly Coupled Chiral HPLC-NMR and HPLC-CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate
Nisha Mistry,Andrew D. Roberts, George E. Tranter,Peter Francis, Ian Barylski, Ismail M. Ismail,§ Jeremy K. Nicholson,| and John C. Lindon
Anal. Chem. 1999, 71, 2838-2843

(R)-cis-5ξ-Methyl Atracurium Dibesylate is chemically (1R,1'R,2R,2'R)-2,2'-((Hexane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) Dibenzenesulfonate. (R)-cis-5ξ-Methyl Atracurium Dibesylate is supplied with detailed characterization data compliant with regulatory guideline. (R)-cis-5ξ-Methyl Atracurium Dibesylate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Atracurium.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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