Pemetrexed EP Impurity E

N° de SZ CAT:	SZ-P014006
Número CAS	182009-04-7
Mol.F.	C20H21N5O6
Peso Molecular	427.4
Status de Fatura	In Stock
Rel. CAS No	937370-10-0 (Disodium salt)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP)

Sinônimo: Pemetrexed R-Isomer

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=C(O)[C@H](NC(C1=CC=C(CCC2=CNC(NC(N)=N3)=C2C3=O)C=C1)=O)CCC(O)=O

A stability-indicating LC-MS/MS method optimization for Pemetrexed through design of experiments: Identification and characterization of major oxidative degradation product
By Narenderan, S. T.; Ramesh, J.; Babu, B.; Meyyanathan, S. N.
From Journal of Pharmaceutical and Biomedical Analysis (2020), 183, 113150

A new validated stability-indicating gradient RP-HPLC method for the determination of pemetrexed disodium and its process related substances
By Hemchand, S.; Babu, R. Ravi Chandra; Annapurna, Mukthinuthalapati Mathrusri
From Journal of Drug Delivery and Therapeutics (2019), 9(3Suppl.), 588-610

Content determination of related impurity-L-isomer in Pemetrexed Disodium for injection by HPLC
By Li, Jinhua; Yang, Mei
From Heilongjiang Yiyao (2014), 27(3), 498-500

Pemetrexed EP Impurity E is chemically (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP). It is also known as Pemetrexed R-Isomer. Pemetrexed EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Pemetrexed EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pemetrexed.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

N° de SZ CAT:	: SZ-P014001
Número CAS	: 150399-23-8
Mol.F.	: C20H21N5O6 : 2Na
Peso Molecular	: 427.4 : 2(23.0)
Status de Fatura	: In Stock
Rel. CAS No	: 137281-23-3 (free base)
Rel. CAT No	: SZ-P014029 ,

N° de SZ CAT:	: SZ-P014029
Número CAS	: 137281-23-3
Mol.F.	: C20H21N5O6
Peso Molecular	: 427.4
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 150399-23-8 (disodium salt) ; 357166-30-4 (disodium hemipentahydrate)
Rel. CAT No	: SZ-P014001 ,

Pemetrexed EP Impurity E

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N° de SZ CAT:	: SZ-P014007
Número CAS	: 193281-00-4
Mol.F.	: C20H21N5O7
Peso Molecular	: 443.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014009
Número CAS	: NA
Mol.F.	: C26H30N6O9
Peso Molecular	: 570.6
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014006
Número CAS	: 182009-04-7
Mol.F.	: C20H21N5O6
Peso Molecular	: 427.4
Status de Fatura	: In Stock
Rel. CAS No	: 937370-10-0 (Disodium salt)

N° de SZ CAT:	: SZ-P014005
Número CAS	: 144051-68-3
Mol.F.	: C25H28N6O9
Peso Molecular	: 556.5
Status de Fatura	: Limited Stock
Rel. CAS No	: 1265908-59-5 (Trisodium salt)

N° de SZ CAT:	: SZ-P014010
Número CAS	: 1265908-64-2
Mol.F.	: C21H23N5O6
Peso Molecular	: 441.4
Status de Fatura	: In Stock
Rel. CAS No	: 1265908-60-8 (Na salt)

N° de SZ CAT:	: SZ-P014012
Número CAS	: 1265908-63-1
Mol.F.	: C21H23N5O6
Peso Molecular	: 441.4
Status de Fatura	: In Stock
Rel. CAS No	: 1265908-61-9 (Na salt)

N° de SZ CAT:	: SZ-P014002
Número CAS	: 869791-42-4
Mol.F.	: C21H23N5O6
Peso Molecular	: 441.4
Status de Fatura	: In Stock
Rel. CAS No	: 2243918-27-4 (Na salt)

N° de SZ CAT:	: SZ-P014003
Número CAS	: 1802552-04-0
Mol.F.	: C40H40N10O13
Peso Molecular	: 868.8
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014004
Número CAS	: 1802552-16-4
Mol.F.	: C40H40N10O13
Peso Molecular	: 868.8
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014013
Número CAS	: 155405-81-5
Mol.F.	: C22H25N5O6
Peso Molecular	: 455.5
Status de Fatura	: In Stock
Rel. CAS No	: 1350616-69-1 (HCl salt)

N° de SZ CAT:	: SZ-P014014
Número CAS	: 193281-05-9
Mol.F.	: C19H21N5O7
Peso Molecular	: 431.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014015
Número CAS	: NA
Mol.F.	: C25H28N6O9
Peso Molecular	: 556.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014016
Número CAS	: 1644286-34-9
Mol.F.	: C40H40N10O13
Peso Molecular	: 868.8
Status de Fatura	: In Stock
Rel. CAS No	: 2368830-32-2 (Tetrasodium salt)

N° de SZ CAT:	: SZ-P014008
Número CAS	: 193265-47-3
Mol.F.	: C15H14N4O4
Peso Molecular	: 314.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014017
Número CAS	: 1644286-36-1
Mol.F.	: C20H21N5O8
Peso Molecular	: 459.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014018
Número CAS	: 1644286-35-0
Mol.F.	: C20H21N5O8
Peso Molecular	: 459.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014019
Número CAS	: NA
Mol.F.	: C43H46N10O15
Peso Molecular	: 942.9
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014020
Número CAS	: NA
Mol.F.	: C30H38N6O9
Peso Molecular	: 626.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014021
Número CAS	: NA
Mol.F.	: C20H23N5O8
Peso Molecular	: 461.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014022
Número CAS	: NA
Mol.F.	: C20H22N4O7
Peso Molecular	: 430.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014D01
Número CAS	: 1129408-57-6
Mol.F.	: C20H16D5N5O6
Peso Molecular	: 432.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014023
Número CAS	: 2518419-18-4
Mol.F.	: C24H30N6O8
Peso Molecular	: 530.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014024
Número CAS	: NA
Mol.F.	: C20H21N5O7
Peso Molecular	: 443.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014025
Número CAS	: NA
Mol.F.	: C20H21N5O8
Peso Molecular	: 459.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014026
Número CAS	: 137281-39-1
Mol.F.	: C15H14N4O3
Peso Molecular	: 298.3
Status de Fatura	: In Stock
Rel. CAS No	: 1007376-45-5 (Na salt)

N° de SZ CAT:	: SZ-P014011
Número CAS	: 155405-80-4
Mol.F.	: C16H16N4O3
Peso Molecular	: 312.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014027
Número CAS	: NA
Mol.F.	: C21H25N5O8
Peso Molecular	: 475.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014028
Número CAS	: 1417656-72-4
Mol.F.	: C20H23N5O9
Peso Molecular	: 477.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P014031
Número CAS	: NA
Mol.F.	: C25H28N6O9 : 2(H2O)
Peso Molecular	: 556.5 : 2(18.0)
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P014032
Número CAS	: NA
Mol.F.	: C20H21N5O6 : H2O
Peso Molecular	: 427.4 : 18.0
Status de Fatura	: In Stock