Olopatadine Hydroxyethyl Impurity

Chromatographic Analysis of Olopatadine in Hydrophilic Interaction Liquid Chromatography
Jelena Maksić, Marko Jovanović, Tijana Rakić, Igor Popović, Darko Ivanović, Biljana Jančić-Stojanović
Journal of Chromatographic Science, Volume 53, Issue 5, May/June 2015, Pages 680–686,
 
Isolation and Characterization Photo Degradation Impurities of Drug Product Olopatadine Hydrochloride by Spectral Techniques
Shivaji Jadhav, Amit Gosar , Amit Jadkar , Rajesh Ankam , Chandrakant Dhatrak
Chemical and Biomolecular Engineering 2019; 4(2): 31-36
 
Application of high performance liquid chromatographic technique for olopatadine hydrochloride and its impurity in ophthalmic solution
r. v. rele* and c. b. warkar
Int. J. Chem. Sci.: 9(2), 2011, 601-614

Olopatadine Hydroxyethyl Impurity is chemically (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-ethanol. It is also known as Olopatadine methanol. Olopatadine Hydroxyethyl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Olopatadine Hydroxyethyl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Olopatadine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.