Nicardipine EP Impurity A (HCl)

N° de SZ CAT:	SZ-N004003
Número CAS	1216817-27-4
Mol.F.	C26H27N3O6 : HCl
Peso Molecular	477.5 : 36.5
Status de Fatura	In Stock
Rel. CAS No	59875-58-0 (free base) ; 2771193-14-5 (Oxalate salt)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: 2-[Benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Hydrochloride (as per EP) ; 3-{2-[Benzyl(methyl)amino]ethyl}5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride (as per USP)

Sinônimo: Nicardipine USP Related Compound B ; Nicardipine Pyridine Analog (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=C(C1=C(C2=CC=CC([N+]([O-])=O)=C2)C(C(OCCN(CC3=CC=CC=C3)C)=O)=C(C)N=C1C)OC.Cl

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181

Nicardipine EP Impurity A (HCl) is chemically 2-[Benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Hydrochloride (as per EP) ; 3-{2-[Benzyl(methyl)amino]ethyl}5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride (as per USP). It is also known as Nicardipine USP Related Compound B ; Nicardipine Pyridine Analog (USP). Nicardipine EP Impurity A (HCl) is supplied with detailed characterization data compliant with regulatory guideline. Nicardipine EP Impurity A (HCl) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nicardipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Nicardipine EP Impurity A (HCl)

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N° de SZ CAT:	: SZ-N004001
Número CAS	: 54527-84-3
Mol.F.	: C26H29N3O6 : HCl
Peso Molecular	: 479.5 : 36.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004002
Número CAS	: 74936-72-4
Mol.F.	: C16H16N2O6
Peso Molecular	: 332.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004003
Número CAS	: 1216817-27-4
Mol.F.	: C26H27N3O6 : HCl
Peso Molecular	: 477.5 : 36.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004004
Número CAS	: 21881-77-6
Mol.F.	: C17H18N2O6
Peso Molecular	: 346.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004005
Número CAS	: 499-81-0
Mol.F.	: C7H5NO4
Peso Molecular	: 167.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004006
Número CAS	: 87625-92-1
Mol.F.	: C15H15NO5
Peso Molecular	: 289.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004007
Número CAS	: 40055-37-6
Mol.F.	: C8H8N2O
Peso Molecular	: 148.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004008
Número CAS	: 71784-27-5
Mol.F.	: C35H40N4O6 : 2(HCl)
Peso Molecular	: 612.7 : 2(36.5)
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004009
Número CAS	: 76258-20-3
Mol.F.	: C17H16N2O6
Peso Molecular	: 344.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004010
Número CAS	: 64603-72-1
Mol.F.	: C16H14N2O6
Peso Molecular	: 330.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004011
Número CAS	: 10323-98-5
Mol.F.	: C13H13NO3
Peso Molecular	: 231.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004012
Número CAS	: 2469735-68-8
Mol.F.	: C15H15NO5
Peso Molecular	: 289.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004D01
Número CAS	: 1432061-50-1
Mol.F.	: C26H26D3N3O6 : HCl
Peso Molecular	: 482.6 : 36.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004013
Número CAS	: NA
Mol.F.	: C15H17NO6
Peso Molecular	: 307.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004015
Número CAS	: 206976-29-6
Mol.F.	: C17H18N2O5
Peso Molecular	: 330.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004016
Número CAS	: NA
Mol.F.	: C26H28N4O7
Peso Molecular	: 508.5
Status de Fatura	: Inquire

N° de SZ CAT:	: SZ-N004017
Número CAS	: 101-98-4
Mol.F.	: C10H15NO
Peso Molecular	: 165.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004018
Número CAS	: 58368-87-9
Mol.F.	: C19H23N3O6
Peso Molecular	: 389.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004019
Número CAS	: 123973-71-7
Mol.F.	: C25H27N3O6
Peso Molecular	: 465.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004020
Número CAS	: NA
Mol.F.	: C26H28N2O7
Peso Molecular	: 480.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004022
Número CAS	: 89267-41-4
Mol.F.	: C18H18N2O6
Peso Molecular	: 358.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004023
Número CAS	: 2724510-66-9
Mol.F.	: C26H29N3O7
Peso Molecular	: 495.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-N004024
Número CAS	: NA
Mol.F.	: C33H34N4O9
Peso Molecular	: 630.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004025
Número CAS	: NA
Mol.F.	: C33H34N4O9
Peso Molecular	: 630.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004026
Número CAS	: NA
Mol.F.	: C33H34N4O9
Peso Molecular	: 630.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004027
Número CAS	: NA
Mol.F.	: C19H22N4O7
Peso Molecular	: 418.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004028
Número CAS	: NA
Mol.F.	: C26H32N4O7
Peso Molecular	: 512.6
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004029
Número CAS	: 2771193-14-5
Mol.F.	: C26H27N3O6 : C2H2O4
Peso Molecular	: 477.5 : 90.0
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-N004030
Número CAS	: NA
Mol.F.	: C25H26N4O7
Peso Molecular	: 494.5
Status de Fatura	: Custom Synthesis