Metoprolol EP Impurity O (HCl salt)

N° de SZ CAT:	SZ-M021017
Número CAS	1486464-40-7
Mol.F.	C27H41NO6 : HCl
Peso Molecular	475.6 : 36.5
Status de Fatura	In Stock
Rel. CAS No	154784-36-8 (free base)

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Nome Químico: Mixture of the 3 stereoisomers of 1,1′-[(1-methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]propan-2-ol] Hydrochloride (as per EP)

Sinônimo: Metoprolol USP Related Compound D

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: COCCC1=CC=C(OCC(O)CN(C(C)C)CC(O)COC2=CC=C(CCOC)C=C2)C=C1.Cl

Identification of a new by-product detected in metoprolol tartrate
magnus erickson,$ karl-erik karlsson,$ bo lamm,§ sam larsson,$ lars a. svensson$ and jorgen vessman
Journal of Pharmaceutical & Biomedical Analysis, Vol. 13, No. 4/5, pp. 567-574, 1995

An improved validated HPLC method for separation of metoprolol and hydrochlorothiazide impurities in metoprolol and hydrochlorothiazide tablets
Avinash S. Patil, Shakil S. Sait, Abhijit Deshamukh and Girish Deshpande
Der Pharmacia Lettre, 2015, 7 (2):183-190

Simultaneous Quantitative Determination of Metoprolol, Atorvastatin and Ramipril in Capsules by a Validated Stability-Indicating RP-UPLC Method
raja kumar seshadri * 1 , makarand madhukar desai 1 , thummala veera raghavaraju 1 , deepa krishnan 1 , dama venugopala rao 1 , ivon elisha chakravarthy
Sci Pharm. 2010; 78: 821–834

Development and validation of a stability indicating RP-HPLC method for determination of metoprolol succinate in pharmaceutical dosage forms
1CH. Naveen Kumar*, 1 Saraswathi Mannuri, 1Vijaya Kuchana and 2N. Kannappan
Der Pharmacia Sinica, 2014, 5(6):69-78

Metoprolol EP Impurity O (HCl salt) is chemically Mixture of the 3 stereoisomers of 1,1′-[(1-methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]propan-2-ol] Hydrochloride (as per EP). It is also known as Metoprolol USP Related Compound D . Metoprolol EP Impurity O (HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. Metoprolol EP Impurity O (HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Metoprolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

N° de SZ CAT:	: SZ-M021007
Número CAS	: 1639933-77-9
Mol.F.	: C13H19NO3 : C4H4O4
Peso Molecular	: 237.3 : 116.1
Status de Fatura	: Under Synthesis
Rel. CAS No	: 29122-74-5 (free base) ; 1956321-87-1 (HCl salt)
Rel. CAT No	: SZ-B003011 ,

N° de SZ CAT:	: SZ-M021040
Número CAS	: 123910-88-3
Mol.F.	: C12H16O3
Peso Molecular	: 208.3
Status de Fatura	: In Stock
Rel. CAT No	: SZ-P014037 ,

Metoprolol EP Impurity O (HCl salt)

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N° de SZ CAT:	: SZ-M021029
Número CAS	: 29112-40-1
Mol.F.	: C16H25NO4
Peso Molecular	: 295.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021030
Número CAS	: 29121-23-1
Mol.F.	: C15H23NO4
Peso Molecular	: 281.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021031
Número CAS	: NA
Mol.F.	: C14H20NO4 : Na
Peso Molecular	: 266.3 : 23.0
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 56392-14-4 (free base) ; 207287-28-3 (HCl salt)

N° de SZ CAT:	: SZ-M021032
Número CAS	: 230975-30-1
Mol.F.	: C21H28O5
Peso Molecular	: 360.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021005
Número CAS	: 109632-08-8
Mol.F.	: C14H23NO3
Peso Molecular	: 253.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021006
Número CAS	: 56718-71-9
Mol.F.	: C9H12O2
Peso Molecular	: 152.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021008
Número CAS	: 62572-90-1
Mol.F.	: C12H18O4
Peso Molecular	: 226.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021009
Número CAS	: 163685-38-9
Mol.F.	: C15H25NO3
Peso Molecular	: 267.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021010
Número CAS	: 7695-63-8
Mol.F.	: C12H19NO2
Peso Molecular	: 209.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021011
Número CAS	: 501-94-0
Mol.F.	: C8H10O2
Peso Molecular	: 138.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021012
Número CAS	: NA
Mol.F.	: C14H23NO3 : HCl
Peso Molecular	: 253.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 62572-94-5 (free base)

N° de SZ CAT:	: SZ-M021014
Número CAS	: 163685-37-8
Mol.F.	: C18H31NO5
Peso Molecular	: 341.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021015
Número CAS	: 73313-36-7
Mol.F.	: C9H22N2O : 2HCl
Peso Molecular	: 174.3 : 2(36.5)
Status de Fatura	: In Stock
Rel. CAS No	: 343785-33-1 (free base)

N° de SZ CAT:	: SZ-M021016
Número CAS	: NA
Mol.F.	: C6H15NO2 : HCl
Peso Molecular	: 133.2 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 6452-57-9 (free base) ; 73313-34-5 (oxalate salt)

N° de SZ CAT:	: SZ-M021017
Número CAS	: 1486464-40-7
Mol.F.	: C27H41NO6 : HCl
Peso Molecular	: 475.6 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 154784-36-8 (free base)
Rel. CAT No	: SZ-M021056 ,

N° de SZ CAT:	: SZ-M021018
Número CAS	: 76805-25-9
Mol.F.	: C13H16O4
Peso Molecular	: 236.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021019
Número CAS	: 122-60-1
Mol.F.	: C9H10O2
Peso Molecular	: 150.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021020
Número CAS	: 104857-48-9
Mol.F.	: C11H14O3
Peso Molecular	: 194.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021021
Número CAS	: 17138-28-2
Mol.F.	: C10H12O3
Peso Molecular	: 180.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021022
Número CAS	: 56718-70-8
Mol.F.	: C12H16O3
Peso Molecular	: 208.3
Status de Fatura	: In Stock

Metoprolol EP Impurity O (HCl salt)

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N° de SZ CAT:	: SZ-M021023
Número CAS	: 81024-43-3
Mol.F.	: C15H25NO3
Peso Molecular	: 267.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021024
Número CAS	: 81024-42-2
Mol.F.	: C15H25NO3
Peso Molecular	: 267.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021025
Número CAS	: 98418-47-4
Mol.F.	: C15H25NO3 : 1/2(C4H6O4)
Peso Molecular	: 267.4 : 1/2(118.1)
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021026
Número CAS	: 56392-17-7
Mol.F.	: C15H25NO3.C4H6O6
Peso Molecular	: 267.37 ; 150.1
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021027
Número CAS	: 56718-76-4
Mol.F.	: C12H17ClO3
Peso Molecular	: 244.7
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021028
Número CAS	: 538-43-2
Mol.F.	: C9H12O3
Peso Molecular	: 168.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M021033
Número CAS	: NA
Mol.F.	: C28H47NO11
Peso Molecular	: 573.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021D01
Número CAS	: 959786-79-9
Mol.F.	: C15H20D5NO3
Peso Molecular	: 272.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021D02
Número CAS	: 959787-96-3
Mol.F.	: C15H18D7NO3
Peso Molecular	: 274.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-M021D03
Número CAS	: NA
Mol.F.	: C27H31D10NO6
Peso Molecular	: 485.7
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 154784-36-8 (Unlabeled)