Ketoconazole Impurity 4

N° de SZ CAT:	SZ-K001014
Número CAS	170210-39-6
Mol.F.	C18H15BrCl2O4
Peso Molecular	446.1
Status de Fatura	Custom Synthesis

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: ((2R,4R)-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: ClC1=CC=C([C@@]2(O[C@@H](COC(C3=CC=CC=C3)=O)CO2)CBr)C(Cl)=C1

Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresis–mass spectrometry
Mar´ıa Castro-Puyana a, Carmen Garc´ıa-Ruiz a, Alejandro Cifuentes b, Antonio L. Crego a, Maria Luisa Marina
Journal of Chromatography A, 1114 (2006) 170–177

Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor
Aneta Grycová , Aneta Dořičáková 1, Zdeněk Dvořák
Toxicol Lett . 2015 Dec 3;239(2):67-72

Ion-pairing liquid chromatographic method determination of ketoconazole and stress degradation in pharmaceutical formulations with fluorescence detection
Wisanu Thongchai
Brazilian Journal of Pharmaceutical Sciences Sci. vol.56

Development and Validation of Stability-Indicating Method for the Simultaneous Determination of Ketoconazole and Beauvericin in Pharmaceutical Tablets
Tingting Tian, Min Yang, Zhongxi Zhao, Yuxia Luan, Xuan Tang, Meihua Zhu, Yan Liu
Journal of Chromatographic Science, Volume 54, Issue 3, 1 March 2016, Pages 361–366

Ketoconazole Impurity 4 is chemically ((2R,4R)-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate. Ketoconazole Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Ketoconazole Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ketoconazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Ketoconazole Impurity 4

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N° de SZ CAT:	: SZ-K001001
Número CAS	: 65277-42-1
Mol.F.	: C26H28Cl2N4O4
Peso Molecular	: 531.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001002
Número CAS	: 254912-63-5
Mol.F.	: C26H26Cl2N4O4
Peso Molecular	: 529.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001003
Número CAS	: 1346598-39-7
Mol.F.	: C38H42Cl2N6O6
Peso Molecular	: 749.7
Status de Fatura	: Limited Stock

N° de SZ CAT:	: SZ-K001004
Número CAS	: 83374-59-8
Mol.F.	: C26H28Cl2N4O4
Peso Molecular	: 531.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001005
Número CAS	: 67914-61-8
Mol.F.	: C24H26Cl2N4O3
Peso Molecular	: 489.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001006
Número CAS	: 134071-44-6
Mol.F.	: C21H20Cl2N2O5S
Peso Molecular	: 483.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001007
Número CAS	: 170210-42-1
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: Limited Stock

N° de SZ CAT:	: SZ-K001008
Número CAS	: 254912-65-7
Mol.F.	: C26H28Cl2N4O5
Peso Molecular	: 547.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001009
Número CAS	: 98-59-9
Mol.F.	: C7H7ClO2S
Peso Molecular	: 190.7
Status de Fatura	: In Stock, 3-4 days for Dispatch

N° de SZ CAT:	: SZ-K001010
Número CAS	: 372-18-9
Mol.F.	: C6H4F2
Peso Molecular	: 114.1
Status de Fatura	: In Stock, 3-4 days for Dispatch

N° de SZ CAT:	: SZ-K001011
Número CAS	: 581806-59-9
Mol.F.	: C12H14N2O2
Peso Molecular	: 218.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001012
Número CAS	: NA
Mol.F.	: C26H26Cl2N4O4
Peso Molecular	: 529.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001013
Número CAS	: 170210-49-8
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001014
Número CAS	: 170210-39-6
Mol.F.	: C18H15BrCl2O4
Peso Molecular	: 446.1
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001015
Número CAS	: 2234-16-4
Mol.F.	: C8H6Cl2O
Peso Molecular	: 189.0
Status de Fatura	: In Stock, 3-4 days for Dispatch

N° de SZ CAT:	: SZ-K001016
Número CAS	: 1610851-14-3
Mol.F.	: C21H20Cl2N2O5S
Peso Molecular	: 483.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001019
Número CAS	: NA
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001020
Número CAS	: 61441-65-4
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001021
Número CAS	: 67914-60-7
Mol.F.	: C12H16N2O2
Peso Molecular	: 220.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001022
Número CAS	: 84682-23-5
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001023
Número CAS	: 170210-46-5
Mol.F.	: C18H15BrCl2O4
Peso Molecular	: 446.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001025
Número CAS	: 170210-50-1
Mol.F.	: C15H16Cl2N2O5S
Peso Molecular	: 407.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001D01
Número CAS	: 1217766-70-5
Mol.F.	: C26H25D3Cl2N4O4
Peso Molecular	: 534.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001D02
Número CAS	: 1217706-96-1
Mol.F.	: C26H20D8Cl2N4O4
Peso Molecular	: 539.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001026
Número CAS	: NA
Mol.F.	: C26H28Cl2N4O7S
Peso Molecular	: 611.5
Status de Fatura	: Under Synthesis

N° de SZ CAT:	: SZ-K001017
Número CAS	: 2095256-87-2
Mol.F.	: C21H20Cl2N2O5S
Peso Molecular	: 483.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001028
Número CAS	: 61397-58-8
Mol.F.	: C14H14Cl2N2O3
Peso Molecular	: 329.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001018
Número CAS	: NA
Mol.F.	: C26H26Cl2N4O5
Peso Molecular	: 545.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-K001029
Número CAS	: 1334423-12-9
Mol.F.	: C26H29ClN4O4
Peso Molecular	: 497.0
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-K001030
Número CAS	: 98405-42-6
Mol.F.	: C23H25BrCl2N2O4
Peso Molecular	: 544.3
Status de Fatura	: In Stock