Irinotecan EP Impurity A

N° de SZ CAT:	SZ-I010013
Número CAS	158406-44-1
Mol.F.	C31H34N4O6 : HCl : 3(H2O)
Peso Molecular	558.6 : 36.5 : 3(18.0)
Status de Fatura	In Stock
Rel. CAS No	103816-16-6 (free base) ; 207683-84-9 (HCl salt) ; 883718-83-0 (Sulfate salt)

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Nome Químico: (4S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride trihydrate (as per EP); (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride trihydrate (as per USP)

Sinônimo: 11-Desethyl Irinotecan (as per EP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O[C@@](C(OC1)=O)(CC)C2=C1C(N3C(C4=NC5=CC=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C5C=C4C3)=C2)=O.[3H2O].Cl

RP-HPLC method development and validation for the simultaneous estimation of Irinotecan hydrochloride and Capecitabine in Active Pharmaceutical Ingredients (APIs)
By Vijaya Jyothi, M.; Bhargav, E.; Keerthana, B.; Varalakshmi, Devi K.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2018), 9(1), 63-67

Method development, validation and forced degradation studies of Irinotecan in bulk and pharmaceutical dosage form
By Swathi, Koduru; Farooqui, Tahmeena; Muntaha, Sidra Tul; Ayesha, Syeda Amtul; Shama, Syeda; Siddiqui, Sarah Imam
From World Journal of Pharmacy and Pharmaceutical Sciences (2018), 7(8), 996-1009

Irinotecan EP Impurity A is chemically (4S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride trihydrate (as per EP); (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride trihydrate (as per USP) . It is also known as 11-Desethyl Irinotecan (as per EP). Irinotecan EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

N° de SZ CAT:	: SZ-I010002
Número CAS	: 19685-09-7
Mol.F.	: C20H16N2O5
Peso Molecular	: 364.4
Status de Fatura	: In Stock
Rel. CAS No	: 1174930-07-4 (HCl salt) ; 77987-01-0 (Na salt)
Rel. CAT No	: SZ-C064021 ,

N° de SZ CAT:	: SZ-I010003
Número CAS	: 86639-52-3
Mol.F.	: C22H20N2O5
Peso Molecular	: 392.4
Status de Fatura	: In Stock
Rel. CAT No	: SZ-C064018 ,

Irinotecan EP Impurity A

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N° de SZ CAT:	: SZ-I010001
Número CAS	: 136572-09-3
Mol.F.	: C33H38N4O6 : HCl : 3(H2O)
Peso Molecular	: 586.7 : 36.5 : 3(18.0)
Status de Fatura	: In Stock
Rel. CAS No	: 97682-44-5 (free base) ; 100286-90-6 (HCl salt)

N° de SZ CAT:	: SZ-I010005
Número CAS	: NA
Mol.F.	: C33H38N4O6 : C2HF3O2
Peso Molecular	: 586.7 : 114.0
Status de Fatura	: In Stock
Rel. CAS No	: 1255644-71-3 (free base) ; 1992961-26-8 (HCl salt)

N° de SZ CAT:	: SZ-I010006
Número CAS	: 78287-27-1
Mol.F.	: C22H20N2O4
Peso Molecular	: 376.4
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-I010007
Número CAS	: 947687-01-6
Mol.F.	: C24H24N2O5
Peso Molecular	: 420.5
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-I010008
Número CAS	: NA
Mol.F.	: C33H38N4O7 : C2HF3O2
Peso Molecular	: 602.7 : 114.0
Status de Fatura	: In Stock
Rel. CAS No	: 185336-12-3 (free base)

N° de SZ CAT:	: SZ-I010010
Número CAS	: 176515-52-9
Mol.F.	: C32H38N4O4
Peso Molecular	: 542.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010012
Número CAS	: 157770-58-6
Mol.F.	: C21H20N2O3
Peso Molecular	: 348.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010013
Número CAS	: 158406-44-1
Mol.F.	: C31H34N4O6 : HCl : 3(H2O)
Peso Molecular	: 558.6 : 36.5 : 3(18.0)
Status de Fatura	: In Stock
Rel. CAS No	: 103816-16-6 (free base) ; 207683-84-9 (HCl salt) ; 883718-83-0 (Sulfate salt)

N° de SZ CAT:	: SZ-I010014
Número CAS	: 947687-02-7
Mol.F.	: C35H42N4O6
Peso Molecular	: 614.7
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-I010015
Número CAS	: NA
Mol.F.	: C32H37N4O5 : Cl
Peso Molecular	: 557.7 : 35.5
Status de Fatura	: In Stock
Rel. CAS No	: 143490-53-3 (free base)

N° de SZ CAT:	: SZ-I010016
Número CAS	: 143490-54-4
Mol.F.	: C32H38N4O5
Peso Molecular	: 558.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010018
Número CAS	: 121080-63-5
Mol.F.	: C28H28N2O11
Peso Molecular	: 568.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 121080-64-6 (Na salt)

N° de SZ CAT:	: SZ-I010019
Número CAS	: 2656-50-0
Mol.F.	: C8H9NO2 : HCl
Peso Molecular	: 151.2 : 18.0
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 30954-71-3 (Free base)

N° de SZ CAT:	: SZ-I010D01
Número CAS	: 1309283-21-3
Mol.F.	: C22H16D4N2O5
Peso Molecular	: 396.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010D02
Número CAS	: 718612-62-5
Mol.F.	: C33H28D10N4O6 : HCl
Peso Molecular	: 596.8 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 718613-28-6 (free base)

N° de SZ CAT:	: SZ-I010020
Número CAS	: NA
Mol.F.	: C24H24N2O5 : C2HF3O2
Peso Molecular	: 420.5 : 114.0
Status de Fatura	: Limited Stock
Rel. CAS No	: 947687-01-6 (free base)

N° de SZ CAT:	: SZ-I010021
Número CAS	: 200619-21-2
Mol.F.	: C22H20N2O6
Peso Molecular	: 408.4
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010022
Número CAS	: NA
Mol.F.	: C12H21ClN2O2
Peso Molecular	: 260.8
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010023
Número CAS	: NA
Mol.F.	: C35H42N4O7
Peso Molecular	: 630.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010024
Número CAS	: NA
Mol.F.	: C13H23ClN2O2
Peso Molecular	: 274.8
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010011
Número CAS	: NA
Mol.F.	: C35H42N4O6 : C2HF3O2
Peso Molecular	: 614.7 : 114.0
Status de Fatura	: Out of Stock, Custom Synthesis
Rel. CAS No	: 947687-02-7 (free base)

N° de SZ CAT:	: SZ-I010025
Número CAS	: NA
Mol.F.	: C11H19ClN2O2
Peso Molecular	: 246.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010030
Número CAS	: 2508174-07-8
Mol.F.	: C34H40N4O7
Peso Molecular	: 616.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010031
Número CAS	: 7689-03-4
Mol.F.	: C20H16N2O4
Peso Molecular	: 348.4
Status de Fatura	: In Stock
Rel. CAS No	: 72517-83-0 (Na salt)

N° de SZ CAT:	: SZ-I010032
Número CAS	: NA
Mol.F.	: C31H34N4O5
Peso Molecular	: 542.6
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010033
Número CAS	: 185304-41-0
Mol.F.	: C32H40N4O5
Peso Molecular	: 560.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010034
Número CAS	: 97682-44-5
Mol.F.	: C33H38N4O6
Peso Molecular	: 586.7
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 136572-09-3 (HCl trihydrate) ; 100286-90-6 (HCl salt)

N° de SZ CAT:	: SZ-I010036
Número CAS	: NA
Mol.F.	: C32H36N4O6 : HCl
Peso Molecular	: 572.7 : 36.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-I010037
Número CAS	: 1608617-71-5
Mol.F.	: C32H36N4O6
Peso Molecular	: 572.7
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1608463-33-7 (HCl salt)

N° de SZ CAT:	: SZ-I010038
Número CAS	: 142706-06-7
Mol.F.	: C33H40N4O7
Peso Molecular	: 604.7
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1329502-92-2 (Na salt) ; 509107-82-8 (HCl salt) ; 2216738-99-5 (disodium salt)