Ezetimibe Triol Impurity

N° de SZ CAT:	SZ-E026037
Número CAS	2363086-22-8
Mol.F.	C33H30F2N2OS
Peso Molecular	572.6
Status de Fatura	Custom Synthesis

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Nome Químico: (5R,6S)-1-(4-Fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-3-((S)-2-hydroxy-1-phenylethyl)-6-(4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: FC1=CC=C(N2C(N([C@@H](C3=CC=CC=C3)CO)C([C@H](CC[C@H](O)C4=CC=C(F)C=C4)[C@H]2C5=CC=C(O)C=C5)=O)=O)C=C1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225

Stability-indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874

Stability-indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281

Ezetimibe Triol Impurity is chemically (5R,6S)-1-(4-Fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-3-((S)-2-hydroxy-1-phenylethyl)-6-(4-hydroxyphenyl)dihydropyrimidine-2,4(1H,3H)-dione. Ezetimibe Triol Impurity is supplied with detailed characterization data compliant with regulatory guideline. Ezetimibe Triol Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ezetimibe.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Ezetimibe

N° de SZ CAT:	: SZ-E026001
Número CAS	: 163222-33-1
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe Open-Ring Anhydro Alcohol

N° de SZ CAT:	: SZ-E026003
Número CAS	: 1374250-07-3
Mol.F.	: C24H23F2NO2
Peso Molecular	: 395.5
Status de Fatura	: Custom Synthesis

Ezetimibe 2-Fluorobenzene Isomer (USP)

N° de SZ CAT:	: SZ-E026004
Número CAS	: 2743547-96-6
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe meta-Fluoroaniline Analog (Hydrate)

N° de SZ CAT:	: SZ-E026005
Número CAS	: NA
Mol.F.	: C24H21F2NO3 : H2O
Peso Molecular	: 409.4 : 18.0
Status de Fatura	: Out of Stock

Ezetimibe Benzyl Diol Impurity

N° de SZ CAT:	: SZ-E026006
Número CAS	: 1374250-06-2
Mol.F.	: C31H31F2NO3
Peso Molecular	: 503.6
Status de Fatura	: Custom Synthesis

Ezetimibe Open-Ring Alcohol (Mixture of Diastereomers)

N° de SZ CAT:	: SZ-E026007
Número CAS	: NA
Mol.F.	: C24H25F2NO3
Peso Molecular	: 413.5
Status de Fatura	: In Stock

Ezetimibe meta-Fluorobenzene Isomer

N° de SZ CAT:	: SZ-E026009
Número CAS	: NA
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Custom Synthesis

Ezetimibe (RRR)-Isomer

N° de SZ CAT:	: SZ-E026010
Número CAS	: 1593542-96-1
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Limited Stock

Ezetimibe (RSS)-Isomer

N° de SZ CAT:	: SZ-E026011
Número CAS	: 1478664-18-4
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe 3-Dehydroxy Impurity

N° de SZ CAT:	: SZ-E026012
Número CAS	: 204589-58-2
Mol.F.	: C24H21F2NO2
Peso Molecular	: 393.4
Status de Fatura	: Out of Stock

Ezetimibe Ketone (USP)

N° de SZ CAT:	: SZ-E026013
Número CAS	: 191330-56-0
Mol.F.	: C24H19F2NO3
Peso Molecular	: 407.4
Status de Fatura	: In Stock

Ezetimibe Benzyl Ether Impurity

N° de SZ CAT:	: SZ-E026014
Número CAS	: 163222-32-0
Mol.F.	: C31H27F2NO3
Peso Molecular	: 499.6
Status de Fatura	: In Stock

Ezetimibe Diacetate

N° de SZ CAT:	: SZ-E026016
Número CAS	: 163380-20-9
Mol.F.	: C28H25F2NO5
Peso Molecular	: 493.5
Status de Fatura	: Custom Synthesis

Ezetimibe (RRS)-Isomer

N° de SZ CAT:	: SZ-E026017
Número CAS	: 163380-16-3
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe Anhydro (E)-Isomer

N° de SZ CAT:	: SZ-E026018
Número CAS	: 204589-68-4
Mol.F.	: C24H19F2NO2
Peso Molecular	: 391.4
Status de Fatura	: Custom Synthesis

Ezetimibe (SSS)-Isomer

N° de SZ CAT:	: SZ-E026019
Número CAS	: 1593543-07-7
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe (RSR)-Isomer

N° de SZ CAT:	: SZ-E026020
Número CAS	: 1376614-99-1
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe 3-O-Acetyl Impurity

N° de SZ CAT:	: SZ-E026021
Número CAS	: 190448-46-5
Mol.F.	: C26H23F2NO4
Peso Molecular	: 451.5
Status de Fatura	: Custom Synthesis

Ezetimibe Tetrahydropyran Impurity

N° de SZ CAT:	: SZ-E026022
Número CAS	: 1296129-15-1
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe Open-Ring Anhydro Acid (Z)-Isomer

N° de SZ CAT:	: SZ-E026023
Número CAS	: NA
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Custom Synthesis

Ezetimibe Anhydro (Z)-Isomer

N° de SZ CAT:	: SZ-E026024
Número CAS	: NA
Mol.F.	: C24H19F2NO2
Peso Molecular	: 391.4
Status de Fatura	: Custom Synthesis

Ezetimibe (SSR)-Isomer

N° de SZ CAT:	: SZ-E026025
Número CAS	: 1593543-00-0
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe Open-Ring Acid

N° de SZ CAT:	: SZ-E026026
Número CAS	: 1618657-29-6
Mol.F.	: C24H23F2NO4
Peso Molecular	: 427.5
Status de Fatura	: Custom Synthesis

Ezetimibe Open-Ring Anhydro Acid

N° de SZ CAT:	: SZ-E026027
Número CAS	: NA
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Custom Synthesis

Ezetimibe (3R,4R,3'S)-Isomer

N° de SZ CAT:	: SZ-E026028
Número CAS	: 1478664-02-6
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: In Stock

Ezetimibe Aniline Impurity

N° de SZ CAT:	: SZ-E026029
Número CAS	: 1354716-98-5
Mol.F.	: C24H22F2N2O2
Peso Molecular	: 408.5
Status de Fatura	: Custom Synthesis

Ezetimibe Desfluoro Chloro Impurity

N° de SZ CAT:	: SZ-E026030
Número CAS	: 1700622-08-7
Mol.F.	: C24H21ClFNO3
Peso Molecular	: 425.9
Status de Fatura	: Custom Synthesis

4”DeFluoro-4”methyl-Ezetimibe

N° de SZ CAT:	: SZ-E026031
Número CAS	: 1700622-07-6
Mol.F.	: C25H24FNO3
Peso Molecular	: 405.5
Status de Fatura	: Custom Synthesis

Ezetimibe Benzyl Impurity (MBZT-2)

N° de SZ CAT:	: SZ-E026032
Número CAS	: 851860-29-2
Mol.F.	: C31H27F2NO3
Peso Molecular	: 499.6
Status de Fatura	: In Stock

Ezetimibe Impurity 27

N° de SZ CAT:	: SZ-E026033
Número CAS	: 934245-16-6
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Custom Synthesis

Ezetimibe Impurity 1

N° de SZ CAT:	: SZ-E026034
Número CAS	: NA
Mol.F.	: C24H21F2NO3
Peso Molecular	: 409.4
Status de Fatura	: Custom Synthesis

Ezetimibe Impurity 16

N° de SZ CAT:	: SZ-E026035
Número CAS	: 189028-95-3
Mol.F.	: C20H20FNO4
Peso Molecular	: 357.5
Status de Fatura	: In Stock

(R)-Ezetimibe Desfluoro Chloro Impurity

N° de SZ CAT:	: SZ-E026036
Número CAS	: NA
Mol.F.	: C24H21ClFNO3
Peso Molecular	: 425.9
Status de Fatura	: Custom Synthesis