Delafloxacin Dimer Impurity

Development and validation of a novel UPLC-​MS​/MS method for quantification of delafloxacin in plasma and aqueous humour for pharmacokinetic analyses
By Iqbal, Muzaffar; Ezzeldin, Essam; Herqash, Rashed Naji; Anwer, Md. Khalid; Azam, Faizul
From Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2020)
 
Simple and Accurate HPTLC-​Densitometric Method for Quantification of Delafloxacin (A Novel Fluoroquinolone Antibiotic) in Plasma Samples: Application to Pharmacokinetic Study in Rats
By Alam Prawez; Foudah Ahmed I; Alqarni Mohammed H; Iqbal Muzaffar; Ezzeldin Essam; Khalil Nasr Y; Iqbal Muzaffar; Ezzeldin Essam; Shakeel Faiyaz
From Antibiotics (Basel, Switzerland) (2020), 9(3)
 

Delafloxacin Dimer Impurity is chemically 1-(6-Amino-3,5-difluoropyridin-2-yl)-7-(3-(3-((1-(6-amino-3,5-difluoropyridin-2-yl)-3-carboxy-8-chloro-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)amino)-2-hydroxypropoxy)azetidin-1-yl)-8-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. Delafloxacin Dimer Impurity is supplied with detailed characterization data compliant with regulatory guideline. Delafloxacin Dimer Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Delafloxacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.