Darifenacin Nitrile Impurity (HCl)

N° de SZ CAT:	SZ-D004012
Número CAS	NA
Mol.F.	C28H28N2O : HCl
Peso Molecular	408.5 : 36.5
Status de Fatura	In Stock
Rel. CAS No	252317-48-9 (free base) ; 608127-89-5 (HBr salt)

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Nome Químico: (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidine acetonitrile hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CN(CCC4=CC=C(OCC5)C5=C4)CC3.Cl

Identification, isolation and characterization of dimer impurities in antimuscarinic agent darifenacin hydrobromide
By Gupta, P. Badarinadh; Rao, B. Venkateswara; Douglas, S. Paul; Sharma, Hemant Kumar; Bharathi, D. Vijaya
From World Journal of Pharmaceutical Research (2017), 6(6), 1041-1063

Development and validation of HPLC method for determination of potential genotoxic impurities in darifenacin hydrobromide drug substance
By Patcha, Vinay Kumar; Gajbhiye, Susheela Bhai; Vundavilli, Jagadeesh Kumar; Kothapalli, S. R. Pavan Kumar; Sreenivas, N.; Ray, U. K.
From International Journal of Pharmacy and Pharmaceutical Research (2017), 8(2), 198-208

Development and validation of a stability-indicating RP-HPLC method for determination of darifenacin hydrobromide in bulk drugs
By Nazeerunnisa, Mohammed; Garikapati, Lakshmi; Bethanabhatla, Syama Sundar
From American Journal of Analytical Chemistry (2014), 5(17), 1239-1248

Darifenacin Nitrile Impurity (HCl) is chemically (3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidine acetonitrile hydrochloride. Darifenacin Nitrile Impurity (HCl) is supplied with detailed characterization data compliant with regulatory guideline. Darifenacin Nitrile Impurity (HCl) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darifenacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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1-Tosyl-(3S)-Hydroxy Pyrrolidine

N° de SZ CAT:	: SZ-D004031
Número CAS	: 133034-00-1
Mol.F.	: C11H15NO3S
Peso Molecular	: 241.3
Status de Fatura	: In Stock

1-Tosyl-(3R)-Tosyloxy Pyrrolidine

N° de SZ CAT:	: SZ-D004032
Número CAS	: 133034-02-3
Mol.F.	: C18H21NO5S2
Peso Molecular	: 395.5
Status de Fatura	: In Stock

2,3-Dihydro-5-Vinylbenzofuran

N° de SZ CAT:	: SZ-D004025
Número CAS	: 633335-97-4
Mol.F.	: C10H10O
Peso Molecular	: 146.2
Status de Fatura	: In Stock

Darifenacin Hydrochloride

N° de SZ CAT:	: SZ-D004036
Número CAS	: 586346-94-3
Mol.F.	: C28H30N2O2 : HCl
Peso Molecular	: 426.6 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 133099-04-4 (Free base) ; 133099-07-7 (HBr salt)

Darifenacin 2,3-Dehydro Bromo Impurity

N° de SZ CAT:	: SZ-D004015
Número CAS	: 133034-06-7
Mol.F.	: C10H9BrO
Peso Molecular	: 225.1
Status de Fatura	: In Stock

Darifenacin 3-Hydroxy Impurity

N° de SZ CAT:	: SZ-D004004
Número CAS	: 206048-82-0
Mol.F.	: C28H30N2O3
Peso Molecular	: 442.6
Status de Fatura	: Custom Synthesis

Darifenacin 4-Hydroxy Impurity

N° de SZ CAT:	: SZ-D004016
Número CAS	: 2468796-89-4
Mol.F.	: C28H31BrN2O2
Peso Molecular	: 507.5
Status de Fatura	: Out of Stock, Custom Synthesis
Rel. CAS No	: 2468796-90-7 (HBr salt)

Darifenacin 5-Carboxymethyl Impurity

N° de SZ CAT:	: SZ-D004006
Número CAS	: 69999-16-2
Mol.F.	: C10H10O3
Peso Molecular	: 178.2
Status de Fatura	: In Stock

Darifenacin 7-Bromo Analog

N° de SZ CAT:	: SZ-D004017
Número CAS	: 1391080-43-5
Mol.F.	: C28H29BrN2O2
Peso Molecular	: 505.5
Status de Fatura	: In Stock

Darifenacin 7-Bromoethyl Impurity

N° de SZ CAT:	: SZ-D004018
Número CAS	: 1598271-92-1
Mol.F.	: C10H11BrO
Peso Molecular	: 227.1
Status de Fatura	: Out of Stock, Custom Synthesis

Darifenacin Bromo Impurity

N° de SZ CAT:	: SZ-D004005
Número CAS	: 127264-14-6
Mol.F.	: C10H11BrO
Peso Molecular	: 227.1
Status de Fatura	: In Stock

Darifenacin Carboxylic Acid Impurity

N° de SZ CAT:	: SZ-D004019
Número CAS	: 1048979-16-3
Mol.F.	: C28H29NO3
Peso Molecular	: 427.5
Status de Fatura	: Out of Stock, Custom Synthesis

Darifenacin Cyano Pyrrolidine Impurity

N° de SZ CAT:	: SZ-D004007
Número CAS	: 871505-23-6
Mol.F.	: C18H18N2 : HCl
Peso Molecular	: 262.4 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 133099-11-3 (Free base) ; 1207849-19-1 (Oxalate salt)

Darifenacin Cyano t-BOC Impurity

N° de SZ CAT:	: SZ-D004014
Número CAS	: 1159977-31-7
Mol.F.	: C23H26N2O2
Peso Molecular	: 362.5
Status de Fatura	: In Stock

Darifenacin D4

N° de SZ CAT:	: SZ-D004D01
Número CAS	: 1095598-84-7
Mol.F.	: C28H26D4N2O2
Peso Molecular	: 430.6
Status de Fatura	: Custom Synthesis

Darifenacin DBE Isomer

N° de SZ CAT:	: SZ-D004008
Número CAS	: NA
Mol.F.	: C28H30N2O2
Peso Molecular	: 426.6
Status de Fatura	: Custom Synthesis

Darifenacin Dimer-1 Impurity

N° de SZ CAT:	: SZ-D004010
Número CAS	: NA
Mol.F.	: C38H40N2O3
Peso Molecular	: 572.7
Status de Fatura	: Custom Synthesis

Darifenacin Dimer-2 Impurity

N° de SZ CAT:	: SZ-D004011
Número CAS	: 2280857-32-9
Mol.F.	: C38H40N2O3
Peso Molecular	: 572.7
Status de Fatura	: In Stock

Darifenacin Hydrobromide

N° de SZ CAT:	: SZ-D004001
Número CAS	: 133099-07-7
Mol.F.	: C28H30N2O2 : HBr
Peso Molecular	: 426.6 : 80.9
Status de Fatura	: In Stock
Rel. CAS No	: 133099-04-4 (Free base)

Darifenacin Impurity (UK-156961)

N° de SZ CAT:	: SZ-D004024
Número CAS	: 206048-83-1
Mol.F.	: C28H32N2O3
Peso Molecular	: 444.6
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 1

N° de SZ CAT:	: SZ-D004033
Número CAS	: 133099-09-9
Mol.F.	: C25H24N2O2S
Peso Molecular	: 416.6
Status de Fatura	: In Stock

Darifenacin Impurity 10 (Tartrate salt)

N° de SZ CAT:	: SZ-D004047
Número CAS	: 1092540-94-7
Mol.F.	: C18H20N2O : C4H6O6
Peso Molecular	: 280.4 : 150.1
Status de Fatura	: In Stock
Rel. CAS No	: 134002-27-0 (Free base)

Darifenacin Impurity 11

N° de SZ CAT:	: SZ-D004068
Número CAS	: 1229355-35-4
Mol.F.	: C18H18N2 : HBr
Peso Molecular	: 262.4 : 80.9
Status de Fatura	: In Stock
Rel. CAS No	: 133099-12-4 (free base)

Darifenacin Impurity 11

N° de SZ CAT:	: SZ-D004048
Número CAS	: 1048979-15-2
Mol.F.	: C27H29NO
Peso Molecular	: 383.5
Status de Fatura	: In Stock

Darifenacin Impurity 12

N° de SZ CAT:	: SZ-D004049
Número CAS	: NA
Mol.F.	: C27H29NO
Peso Molecular	: 383.5
Status de Fatura	: In Stock

Darifenacin Impurity 12

N° de SZ CAT:	: SZ-D004069
Número CAS	: NA
Mol.F.	: C28H28N2O : HBr
Peso Molecular	: 408.5 : 80.9
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 13

N° de SZ CAT:	: SZ-D004052
Número CAS	: NA
Mol.F.	: C46H46N4O4
Peso Molecular	: 718.9
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 2

N° de SZ CAT:	: SZ-D004034
Número CAS	: 133099-10-2
Mol.F.	: C25H24N2O2S
Peso Molecular	: 416.6
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 3

N° de SZ CAT:	: SZ-D004037
Número CAS	: 86-29-3
Mol.F.	: C14H11N
Peso Molecular	: 193.3
Status de Fatura	: In Stock

Darifenacin Impurity 5

N° de SZ CAT:	: SZ-D004038
Número CAS	: NA
Mol.F.	: C20H22O6S2
Peso Molecular	: 422.5
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 6

N° de SZ CAT:	: SZ-D004039
Número CAS	: 133034-07-8
Mol.F.	: C28H28N2O3
Peso Molecular	: 440.6
Status de Fatura	: In Stock
Rel. CAS No	: 133034-08-9 (HCl salt)

Darifenacin Impurity 7

N° de SZ CAT:	: SZ-D004040
Número CAS	: NA
Mol.F.	: C19H22N2O
Peso Molecular	: 294.4
Status de Fatura	: Custom Synthesis

Darifenacin Impurity 8

N° de SZ CAT:	: SZ-D004044
Número CAS	: 87776-76-9
Mol.F.	: C10H12O2
Peso Molecular	: 164.2
Status de Fatura	: In Stock

Darifenacin Impurity 9

N° de SZ CAT:	: SZ-D004046
Número CAS	: 142935-60-2
Mol.F.	: C10H8O3
Peso Molecular	: 176.2
Status de Fatura	: In Stock

Darifenacin Impurity B

N° de SZ CAT:	: SZ-D004045
Número CAS	: 136081-60-2
Mol.F.	: C11H14O4S
Peso Molecular	: 242.3
Status de Fatura	: Out of Stock

Darifenacin Impurity E

N° de SZ CAT:	: SZ-D004027
Número CAS	: 1797983-04-0
Mol.F.	: C38H40N2O3
Peso Molecular	: 572.7
Status de Fatura	: Out of Stock

Darifenacin Impurity H

N° de SZ CAT:	: SZ-D004028
Número CAS	: NA
Mol.F.	: C47H50N4O3
Peso Molecular	: 718.9
Status de Fatura	: In Stock

Darifenacin KSM-I A

N° de SZ CAT:	: SZ-D004041
Número CAS	: 90843-31-5
Mol.F.	: C10H10O2
Peso Molecular	: 162.2
Status de Fatura	: In Stock

Darifenacin KSM-II B Precursor

N° de SZ CAT:	: SZ-D004042
Número CAS	: 133034-01-2
Mol.F.	: C18H21NO5S2
Peso Molecular	: 395.5
Status de Fatura	: Custom Synthesis

Darifenacin KSM-II C Precursor

N° de SZ CAT:	: SZ-D004043
Número CAS	: 943587-25-5
Mol.F.	: C11H15NO3S
Peso Molecular	: 241.3
Status de Fatura	: Custom Synthesis

Darifenacin Morpholine Amide Impurity

N° de SZ CAT:	: SZ-D004035
Número CAS	: 97483-11-9
Mol.F.	: C14H17NO2S
Peso Molecular	: 263.4
Status de Fatura	: In Stock

Darifenacin Nitrile Impurity (HCl)

N° de SZ CAT:	: SZ-D004012
Número CAS	: NA
Mol.F.	: C28H28N2O : HCl
Peso Molecular	: 408.5 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 252317-48-9 (free base) ; 608127-89-5 (HBr salt)

Darifenacin Nitroso Impurity 1

N° de SZ CAT:	: SZ-D004070
Número CAS	: NA
Mol.F.	: C18H19N3O2
Peso Molecular	: 309.4
Status de Fatura	: Custom Synthesis

Darifenacin N-Oxide Impurity

N° de SZ CAT:	: SZ-D004020
Número CAS	: 1391080-40-2
Mol.F.	: C28H30N2O3
Peso Molecular	: 442.6
Status de Fatura	: In Stock

Darifenacin Oxidized Impurity

N° de SZ CAT:	: SZ-D004026
Número CAS	: 133033-99-5
Mol.F.	: C28H28N2O2
Peso Molecular	: 424.5
Status de Fatura	: In Stock
Rel. CAS No	: 943034-52-4 (HBr salt)

Darifenacin Pyrrolidin Carboxylic Acid Impurity

N° de SZ CAT:	: SZ-D004021
Número CAS	: 1050646-75-7
Mol.F.	: C18H19NO2
Peso Molecular	: 281.4
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1415566-36-7 (HBr salt)

Darifenacin Pyrrolidine Impurity (S)-Isomer

N° de SZ CAT:	: SZ-D004003
Número CAS	: 134002-26-9
Mol.F.	: C18H20N2O : C4H6O6
Peso Molecular	: 280.4 : 150.1
Status de Fatura	: In Stock
Rel. CAS No	: 134002-25-8 (Free base)

Darifenacin Pyrrolidine Impurity Racemate

N° de SZ CAT:	: SZ-D004013
Número CAS	: 103887-32-7
Mol.F.	: C18H20N2O
Peso Molecular	: 280.4
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 103913-15-1 (HCl salt) ; 1092540-81-2 (HBr salt)

Darifenacin Pyrrolidinium Dimer Impurity

N° de SZ CAT:	: SZ-D004022
Número CAS	: 1396968-57-2
Mol.F.	: C38H41N2O3 : Br
Peso Molecular	: 573.8 : 79.9
Status de Fatura	: In Stock
Rel. CAS No	: 1397321-17-3 (Free base)

Darifenacin Recemic Mixture

N° de SZ CAT:	: SZ-D004054
Número CAS	: 133033-93-9
Mol.F.	: C28H30N2O2
Peso Molecular	: 426.6
Status de Fatura	: Out of Stock
Rel. CAS No	: 1092540-82-3 (HBr salt)

Darifenacin R-Isomer (HCl)

N° de SZ CAT:	: SZ-D004002
Número CAS	: NA
Mol.F.	: C28H30N2O2 : HCl
Peso Molecular	: 426.6 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 133099-05-5 (free base)

Darifenacin Vinyl Impurity (UK-201705)

N° de SZ CAT:	: SZ-D004029
Número CAS	: 1048979-09-4
Mol.F.	: C28H30N2O2
Peso Molecular	: 426.6
Status de Fatura	: In Stock

Darifenacin Vinylbenzofuran Impurity

N° de SZ CAT:	: SZ-D004023
Número CAS	: 633335-98-5
Mol.F.	: C10H8O
Peso Molecular	: 144.2
Status de Fatura	: Custom Synthesis

Darifenacin Nitrile Impurity (HCl)

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