Brimonidine Open Ring Impurity

N° de SZ CAT:	SZ-B026027
Número CAS	134892-47-0
Mol.F.	C11H12BrN5S
Peso Molecular	326.2
Status de Fatura	Custom Synthesis

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Nome Químico: 1-(2-Aminoethyl)-3-(5-bromoquinoxalin-6-yl)thiourea; Thiourea, 1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: BrC(C1=NC=CN=C1C=C2)=C2NC(NCCN)=S

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma
B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.Prausnitz
Journal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma
Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun
ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems
Jianguo Sun, Xiuwen Zhang & Taomin Huang
Chemistry Central Journal volume 11, Article number: 62 (2017)

Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Brimonidine Tartrate in Pure Form, Formulations and Preformulation Studies
Prakash Bhagav 1, Pandurang Deshpande 1, Saurabh Pandey 1 , Sajeev Chandran
Der Pharmacia Lettre, 2010, 2(3): 106-122

Brimonidine Open Ring Impurity is chemically 1-(2-Aminoethyl)-3-(5-bromoquinoxalin-6-yl)thiourea; Thiourea, 1-(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl). Brimonidine Open Ring Impurity is supplied with detailed characterization data compliant with regulatory guideline. Brimonidine Open Ring Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Brimonidine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

N° de SZ CAT:	: SZ-B026006
Número CAS	: NA
Mol.F.	: C9H8BrN5 : C2HF3O2
Peso Molecular	: 266.1 : 114.0
Status de Fatura	: In Stock
Rel. CAS No	: 168329-48-4 (free base) ; 1797986-78-7 (HCl salt)

N° de SZ CAT:	: SZ-B026007
Número CAS	: 151110-15-5
Mol.F.	: C11H8BrN5
Peso Molecular	: 290.1
Status de Fatura	: In Stock
Rel. CAS No	: 151110-16-6 (HCl salt)

N° de SZ CAT:	: SZ-B026008
Número CAS	: 1391054-10-6
Mol.F.	: C11H12BrN5O : C2HF3O2
Peso Molecular	: 310.2 : 114.0
Status de Fatura	: In Stock
Rel. CAS No	: 1216379-05-3 (free base)

N° de SZ CAT:	: SZ-B026045
Número CAS	: 70359-46-5
Mol.F.	: C11H10BrN5 : C4H6O6
Peso Molecular	: 292.1 : 150.1
Status de Fatura	: In Stock
Rel. CAS No	: 59803-98-4 (free base)
Rel. CAT No	: SZ-B026001 ,

N° de SZ CAT:	: SZ-B026001
Número CAS	: 59803-98-4
Mol.F.	: C11H10BrN5
Peso Molecular	: 292.1
Status de Fatura	: In Stock
Rel. CAS No	: 70359-46-5 (Tartrate salt)
Rel. CAT No	: SZ-B026045 ,

Brimonidine Open Ring Impurity

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N° de SZ CAT:	: SZ-B026035
Número CAS	: 1158184-23-6
Mol.F.	: C13H12BrN5O
Peso Molecular	: 334.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026048
Número CAS	: NA
Mol.F.	: C11H10BrN5O
Peso Molecular	: 308.1
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026011
Número CAS	: 182627-95-8
Mol.F.	: C11H10BrN5O2
Peso Molecular	: 324.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026018
Número CAS	: NA
Mol.F.	: C14H14BrN5O2
Peso Molecular	: 364.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026010
Número CAS	: 842138-75-4
Mol.F.	: C11H10BrN3OS
Peso Molecular	: 312.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026002
Número CAS	: 91147-43-2
Mol.F.	: C11H11N5
Peso Molecular	: 213.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026003
Número CAS	: 50358-63-9
Mol.F.	: C8H6BrN3
Peso Molecular	: 224.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026004
Número CAS	: 6298-37-9
Mol.F.	: C8H7N3
Peso Molecular	: 145.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026005
Número CAS	: 842138-74-3
Mol.F.	: C9H7BrN4S
Peso Molecular	: 283.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026023
Número CAS	: 1216379-05-3
Mol.F.	: C11H12BrN5O
Peso Molecular	: 310.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026009
Número CAS	: 91147-46-5
Mol.F.	: C11H10ClN5
Peso Molecular	: 247.7
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026020
Número CAS	: 134892-46-9
Mol.F.	: C9H4BrN3S
Peso Molecular	: 266.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026027
Número CAS	: 134892-47-0
Mol.F.	: C11H12BrN5S
Peso Molecular	: 326.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026015
Número CAS	: 135306-56-8
Mol.F.	: C9H5N3S
Peso Molecular	: 187.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026019
Número CAS	: 182628-02-0
Mol.F.	: C9H5BrN4
Peso Molecular	: 249.1
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026017
Número CAS	: NA
Mol.F.	: C15H12BrN5O4
Peso Molecular	: 406.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026013
Número CAS	: NA
Mol.F.	: C10H8BrN3S
Peso Molecular	: 282.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026014
Número CAS	: 1217439-06-9
Mol.F.	: C13H14N4
Peso Molecular	: 226.3
Status de Fatura	: Limited Stock

N° de SZ CAT:	: SZ-B026016
Número CAS	: NA
Mol.F.	: C23H20Br2N10
Peso Molecular	: 596.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026021
Número CAS	: NA
Mol.F.	: C14H13BrN6O4
Peso Molecular	: 409.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026038
Número CAS	: NA
Mol.F.	: C11H9N5
Peso Molecular	: 211.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026039
Número CAS	: NA
Mol.F.	: C15H14BrN5O5
Peso Molecular	: 424.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026040
Número CAS	: NA
Mol.F.	: C15H12BrN5O4
Peso Molecular	: 406.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026041
Número CAS	: 934548-66-0
Mol.F.	: C15H12BrN5O3
Peso Molecular	: 390.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-B026042
Número CAS	: NA
Mol.F.	: C15H10BrN5O3
Peso Molecular	: 388.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026043
Número CAS	: NA
Mol.F.	: C16H12BrN5O5
Peso Molecular	: 434.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026046
Número CAS	: NA
Mol.F.	: C15H12BrN5O3
Peso Molecular	: 390.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026047
Número CAS	: NA
Mol.F.	: C15H14BrN5O4
Peso Molecular	: 408.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026024
Número CAS	: NA
Mol.F.	: C22H18Br2N10
Peso Molecular	: 582.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-B026025
Número CAS	: NA
Mol.F.	: C15H12BrN5O3
Peso Molecular	: 390.2
Status de Fatura	: Custom Synthesis