Bendamustine D8 Hydrochloride

N° de SZ CAT:	SZ-B010D02
Número CAS	1185068-23-8
Mol.F.	C16H13D8Cl2N3O2 : HCl
Peso Molecular	366.3 : 36.5
Status de Fatura	Custom Synthesis
Rel. CAS No	1134803-33-0 (free base)

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Nome Químico: 4-(5-(Bis(2-chloroethyl-1,1,2,2-d4)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CN1C2=CC=C(N(C([2H])([2H])C([2H])([2H])Cl)C([2H])([2H])C([2H])([2H])Cl)C=C2N=C1CCCC(O)=O.Cl

Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941

Development and validation of a stability-indicating rp-hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187

Novel validated RP-HPLC method for bendamustine hydrochloride based on ion-pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39

Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357

Bendamustine D8 Hydrochloride is chemically 4-(5-(Bis(2-chloroethyl-1,1,2,2-d4)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride. Bendamustine D8 Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Bendamustine D8 Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bendamustine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Bendamustine

N° de SZ CAT:	: SZ-B010007
Número CAS	: 16506-27-7
Mol.F.	: C16H21Cl2N3O2
Peso Molecular	: 358.3
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 3543-75-7 (HCl salt) ; 1374784-02-7 (hydrochloride hydrate)

Bendamustine Amino Isopropyl Ester Impurity

N° de SZ CAT:	: SZ-B010047
Número CAS	: NA
Mol.F.	: C15H21N3O2 : HCl
Peso Molecular	: 275.4 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1313020-26-6 (free base)

Bendamustine D8 Hydrochloride

N° de SZ CAT:	: SZ-B010D02
Número CAS	: 1185068-23-8
Mol.F.	: C16H13D8Cl2N3O2 : HCl
Peso Molecular	: 366.3 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1134803-33-0 (free base)

Bendamustine Deschloroethyl Acid Ethyl Ester

N° de SZ CAT:	: SZ-B010001
Número CAS	: 2517968-40-8
Mol.F.	: C16H22ClN3O2
Peso Molecular	: 323.8
Status de Fatura	: In Stock

Bendamustine Dideschloroethyl Acid Impurity

N° de SZ CAT:	: SZ-B010003
Número CAS	: 914626-62-3
Mol.F.	: C12H15N3O2
Peso Molecular	: 233.3
Status de Fatura	: In Stock
Rel. CAS No	: 1179363-38-2 (HCl salt)

Bendamustine Dimer 2'-Allyl Ester

N° de SZ CAT:	: SZ-B010019
Número CAS	: NA
Mol.F.	: C35H45Cl3N6O4 : HCl
Peso Molecular	: 720.2 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine USP Related Compound B

N° de SZ CAT:	: SZ-B010021
Número CAS	: 2173004-95-8
Mol.F.	: C16H21N3O3 : HCl
Peso Molecular	: 303.4 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 1228552-02-0 (Free base)

Bendamustine Hydrochloride

N° de SZ CAT:	: SZ-B010000
Número CAS	: 3543-75-7
Mol.F.	: C16H202N3O2 : HCl
Peso Molecular	: 358.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 16506-27-7 (free base)

Bendamustine Impurity

N° de SZ CAT:	: SZ-B010015
Número CAS	: NA
Mol.F.	: C32H43ClN6O6 : HCl
Peso Molecular	: 643.2 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1219709-87-1 (free base)

Bendamustine Impurity 1

N° de SZ CAT:	: SZ-B010022
Número CAS	: NA
Mol.F.	: C16H23N3O3 : HCl
Peso Molecular	: 305.4 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1366085-72-4 (free base)

Bendamustine Impurity 10

N° de SZ CAT:	: SZ-B010031
Número CAS	: NA
Mol.F.	: C12H15N3O5 : HCl
Peso Molecular	: 281.3 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 91644-13-2 (free base)

Bendamustine Impurity 11

N° de SZ CAT:	: SZ-B010032
Número CAS	: NA
Mol.F.	: C19H22N6O6 : HCl
Peso Molecular	: 430.4 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 12

N° de SZ CAT:	: SZ-B010033
Número CAS	: NA
Mol.F.	: C19H20N6O5 : HCl
Peso Molecular	: 412.4 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 13

N° de SZ CAT:	: SZ-B010034
Número CAS	: 914626-65-6
Mol.F.	: C19H18N6O4
Peso Molecular	: 394.4
Status de Fatura	: In Stock

Bendamustine Impurity 14

N° de SZ CAT:	: SZ-B010035
Número CAS	: NA
Mol.F.	: C19H22N6 : HCl
Peso Molecular	: 334.4 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 847588-86-7 (free base)

Bendamustine Impurity 15

N° de SZ CAT:	: SZ-B010036
Número CAS	: 1469343-10-9
Mol.F.	: C15H21N2O2
Peso Molecular	: 261.4
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 16

N° de SZ CAT:	: SZ-B010037
Número CAS	: NA
Mol.F.	: C19H27Cl2N3O4
Peso Molecular	: 432.3
Status de Fatura	: In Stock

Bendamustine Impurity 17

N° de SZ CAT:	: SZ-B010038
Número CAS	: NA
Mol.F.	: C18H24ClN3O4
Peso Molecular	: 381.9
Status de Fatura	: Out of Stock

Bendamustine Impurity 18

N° de SZ CAT:	: SZ-B010039
Número CAS	: NA
Mol.F.	: C33H46N6O6 : HCl
Peso Molecular	: 622.8 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 19

N° de SZ CAT:	: SZ-B010040
Número CAS	: 3543-73-5
Mol.F.	: C14H19N3O2
Peso Molecular	: 261.3
Status de Fatura	: In Stock

Bendamustine Impurity 2

N° de SZ CAT:	: SZ-B010023
Número CAS	: NA
Mol.F.	: C16H21Cl2N3O3 : HCl
Peso Molecular	: 374.3 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 20

N° de SZ CAT:	: SZ-B010044
Número CAS	: 2784-96-5
Mol.F.	: C7H9N3O2
Peso Molecular	: 167.2
Status de Fatura	: In Stock
Rel. CAS No	: 879649-75-9 (HCl salt)

Bendamustine Impurity 23

N° de SZ CAT:	: SZ-B010050
Número CAS	: 7441-32-9
Mol.F.	: C30H24O12
Peso Molecular	: 576.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 24

N° de SZ CAT:	: SZ-B010051
Número CAS	: 88-26-6
Mol.F.	: C15H24O2
Peso Molecular	: 236.4
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 25

N° de SZ CAT:	: SZ-B010052
Número CAS	: NA
Mol.F.	: C16H19N3O2S2 : HCl
Peso Molecular	: 349.5 : 36.5
Status de Fatura	: In Stock

Bendamustine Impurity 26

N° de SZ CAT:	: SZ-B010069
Número CAS	: 119548-63-9
Mol.F.	: C14H14N6O5
Peso Molecular	: 346.3
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 27

N° de SZ CAT:	: SZ-B010070
Número CAS	: NA
Mol.F.	: C15H18N6O4
Peso Molecular	: 346.3
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 28

N° de SZ CAT:	: SZ-B010071
Número CAS	: NA
Mol.F.	: C14H14N6O4
Peso Molecular	: 330.3
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 29

N° de SZ CAT:	: SZ-B010072
Número CAS	: NA
Mol.F.	: C15H16N6O2
Peso Molecular	: 312.3
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 3

N° de SZ CAT:	: SZ-B010024
Número CAS	: 60651-29-8
Mol.F.	: C7H11N3
Peso Molecular	: 137.2
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1305319-65-6 (HCl salt)

Bendamustine Impurity 4 (Mixture of Isomers)

N° de SZ CAT:	: SZ-B010025
Número CAS	: NA
Mol.F.	: C28H41Cl2N3O12 : HCl
Peso Molecular	: 682.6 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 5

N° de SZ CAT:	: SZ-B010026
Número CAS	: 1138238-08-0
Mol.F.	: C16H21Cl2N3O3
Peso Molecular	: 374.3
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1258418-50-6 (HCl salt)

Bendamustine Impurity 6

N° de SZ CAT:	: SZ-B010027
Número CAS	: NA
Mol.F.	: C32H42Cl2N6O5 : HCl
Peso Molecular	: 661.6 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 7 (HCl)

N° de SZ CAT:	: SZ-B010028
Número CAS	: NA
Mol.F.	: C15H19Cl2N3O3 : HCl
Peso Molecular	: 360.3 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 8

N° de SZ CAT:	: SZ-B010029
Número CAS	: NA
Mol.F.	: C18H26ClN3O3 : HCl
Peso Molecular	: 367.9 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Impurity 9

N° de SZ CAT:	: SZ-B010030
Número CAS	: NA
Mol.F.	: C32H43ClN6O6 : HCl
Peso Molecular	: 643.2 : 36.5
Status de Fatura	: Custom Synthesis

Bendamustine Isopropyl Ester

N° de SZ CAT:	: SZ-B010008
Número CAS	: NA
Mol.F.	: C19H27Cl2N3O2 : HCl
Peso Molecular	: 400.3 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1313020-25-5 (free base)

Bendamustine Methyl Ester (HCl)

N° de SZ CAT:	: SZ-B010009
Número CAS	: NA
Mol.F.	: C17H23Cl2N3O2 : HCl
Peso Molecular	: 372.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 109882-25-9 (free base)

Bendamustine Monohydroxy Acid Ethyl Ester

N° de SZ CAT:	: SZ-B010010
Número CAS	: 898224-95-8
Mol.F.	: C18H26ClN3O3
Peso Molecular	: 367.9
Status de Fatura	: In Stock

Bendamustine Monohydroxy Isopropyl Ester Impurity

N° de SZ CAT:	: SZ-B010016
Número CAS	: NA
Mol.F.	: C19H28ClN3O3 : HCl
Peso Molecular	: 381.9 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 1797008-41-3 (free base)

Bendamustine N-Desmethyl Impurity Hydrochloride

N° de SZ CAT:	: SZ-B010059
Número CAS	: 31349-38-9
Mol.F.	: C15H19Cl2N3O2 : HCl
Peso Molecular	: 344.2 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 41515-13-3 (free base)

Bendamustine Nitro Ethyl Ester Impurity

N° de SZ CAT:	: SZ-B010013
Número CAS	: 3543-72-4
Mol.F.	: C14H17N3O4
Peso Molecular	: 291.3
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1678557-24-8 (Sulfate salt)

Bendamustine PEG Ester Mixture

N° de SZ CAT:	: SZ-B010073
Número CAS	: NA
Mol.F.	: NA
Peso Molecular	: NA
Status de Fatura	: Custom Synthesis

Bendamustine Propylene Glycol Ester 1

N° de SZ CAT:	: SZ-B010041
Número CAS	: 1219709-88-2
Mol.F.	: C19H27Cl2N3O3
Peso Molecular	: 416.3
Status de Fatura	: Out of Stock

Bendamustine Propylene Glycol Ester 1 + 2

N° de SZ CAT:	: SZ-B010043
Número CAS	: NA
Mol.F.	: C38H54Cl4N6O6
Peso Molecular	: 832.7
Status de Fatura	: Out of Stock

Bendamustine Propylene Glycol Ester 2

N° de SZ CAT:	: SZ-B010042
Número CAS	: 1219709-89-3
Mol.F.	: C19H27Cl2N3O3
Peso Molecular	: 416.3
Status de Fatura	: Out of Stock

Bendamustine Trihydroxyethyl Dimer Impurity

N° de SZ CAT:	: SZ-B010014
Número CAS	: NA
Mol.F.	: C32H44N6O7 : HCl
Peso Molecular	: 624.7 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1391052-61-1 (free base)

Bendamustine USP Related Compound A

N° de SZ CAT:	: SZ-B010005
Número CAS	: 109882-30-6
Mol.F.	: C16H23N3O4
Peso Molecular	: 321.4
Status de Fatura	: Limited Stock
Rel. CAS No	: 109882-29-3 (HCl salt)

Bendamustine USP Related Compound C

N° de SZ CAT:	: SZ-B010004
Número CAS	: 3543-74-6
Mol.F.	: C18H27N3O4
Peso Molecular	: 349.4
Status de Fatura	: In Stock

Bendamustine USP Related Compound D (HCl salt)

N° de SZ CAT:	: SZ-B010002
Número CAS	: 1797881-48-1
Mol.F.	: C14H18ClN3O2 : HCl
Peso Molecular	: 295.8 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 1219709-86-0 (free base)

Bendamustine USP Related Compound E (HCl)

N° de SZ CAT:	: SZ-B010011
Número CAS	: 109882-26-0
Mol.F.	: C16H22ClN3O3 : HCl
Peso Molecular	: 339.8 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 109882-27-1 (Free base)

Bendamustine USP Related Compound F

N° de SZ CAT:	: SZ-B010020
Número CAS	: 1869075-89-7
Mol.F.	: C22H33Cl2N3O7
Peso Molecular	: 522.4
Status de Fatura	: In Stock
Rel. CAS No	: 1869075-90-0 (HCl salt)

Bendamustine USP Related Compound G

N° de SZ CAT:	: SZ-B010017
Número CAS	: 191939-34-1
Mol.F.	: C16H20ClN3O2S
Peso Molecular	: 353.9
Status de Fatura	: Out of Stock, Custom Synthesis
Rel. CAS No	: 2469039-29-8 (HCl salt)

Bendamustine USP Related Compound G Hydrochloride

N° de SZ CAT:	: SZ-B010061
Número CAS	: 2469039-29-8
Mol.F.	: C16H20ClN3O2S : HCl
Peso Molecular	: 353.9 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 191939-34-1 (free base)

Bendamustine USP Related Compound H

N° de SZ CAT:	: SZ-B010018
Número CAS	: 1228551-91-4
Mol.F.	: C32H41Cl3N6O4
Peso Molecular	: 680.1
Status de Fatura	: In Stock
Rel. CAS No	: 1926162-37-9 (HCl salt)

Bendamustine USP Related Compound I (HCl)

N° de SZ CAT:	: SZ-B010006
Número CAS	: NA
Mol.F.	: C18H25Cl2N3O2 : HCl
Peso Molecular	: 386.3 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 87475-54-5 (free base)

Dihydroxy Bendamustine D3 Hydrochloride

N° de SZ CAT:	: SZ-B010D01
Número CAS	: NA
Mol.F.	: C16H20D3N3O4 : HCl
Peso Molecular	: 324.4 : 36.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1794737-33-9 (free base)

N-Nitroso Bendamustine Impurity

N° de SZ CAT:	: SZ-B010046
Número CAS	: NA
Mol.F.	: C14H17ClN4O3
Peso Molecular	: 324.8
Status de Fatura	: In Stock

Bendamustine D8 Hydrochloride

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