Bortezomib Impurity 42

SZ CAT No:	SZ-B004070
CAS No	477254-69-6
Mol.F.	C15H28BNO2 : C2HF3O2
Mol.Wt.	265.2 : 114.0
Inv. Status	In Stock
Rel. CAS No	477254-68-5 (Free base)

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Chemical Name: (S)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C[C@]([C@@]1([H])C[C@]2([H])C3)(OB([C@H](N)CC(C)C)O1)[C@]3([H])C2(C)C.FC(F)(F)C(O)=O

Novel method development and validation of bortezomib in bulk and pharmaceutical dosage form by RP-HPLC
By Prasanna, Pasupuleti Laxmi; Sandhya, Pedapanga; Geetha, Pittala; Anuhya, Vallapatla M.
From Journal of Drug Delivery and Therapeutics (2019), 9(1), 17-22

Determination of bortezomib in API samples using HPLC: assessment of enantiomeric and diastereomeric impurities
By Kamalzadeh, Zahra; Babanezhad, Esmaeil; Ghaffari, Solmaz; Ezhiyeh, Alireza Mohseni; Mohammadnejad, Mahdieh; Naghibfar, Mehdi; Bararjanian, Morteza; Attar, Hossein
From Journal of Chromatographic Science (2017), 55(7), 697-705

Bortezomib Impurity 42 is chemically (S)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate. Bortezomib Impurity 42 is supplied with detailed characterization data compliant with regulatory guideline. Bortezomib Impurity 42 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bortezomib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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