Chemical Name: 9-Fluoro-16β-methyl-3,20-dioxopregna-1,4-diene-11β,17,21-triyl tripropanoate (as per EP)
Synonym: Betamethasone Tripropionate (EP)
Smiles: C[C@H]1C[C@@]2([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](OC(CC)=O)C[C@]2(C)[C@]1(C(COC(CC)=O)=O)OC(CC)=O)=O
Inchi: InChI=1S/C28H36O7/c1-6-23(31)33-15-21(30)27(35-24(32)7-2)16(3)12-20-19-9-8-17-13-18(29)10-11-25(17,4)28(19)22(34-28)14-26(20,27)5/h10-11,13,16,19-20,22H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,22-,25-,26-,27-,28+/m0/s1
Application of LC–MSn in conjunction with mechanism-based stress studies in the elucidation of drug impurity structure: Rapid identification of a process impurity in betamethasone 17-valerate drug substance
Min Li, Mingxiang Lin, Abu Rustum
Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 1451–1456
Development and Validation of Stability-indicating HPLC Method for Betamethoasone Dipropionate and Related Substances in Topical Formulation
A. s. vairale*, p. sivaswaroop1 and s. bandana
Indian Journal of Pharmaceutical Sciences 74(2):107-15