Bendamustine USP Related Compound G

SZ CAT No:	SZ-B010017
CAS No	191939-34-1
Mol.F.	C16H20ClN3O2S
Mol.Wt.	353.9
Inv. Status	Out of Stock, Custom Synthesis
Rel. CAS No	2469039-29-8 (HCl salt)

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Chemical Name: 4-[6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methylimidazo[4,5-h][1,4]benzothiazin-2-yl]butanoic acid (as per USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC(CCCC1=NC2=C(N1C)C=CC3=C2SCCN3CCCl)=O

Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions
By Gaztanaga, Pablo; Baggio, Ricardo; Vega, Daniel Roberto
From Acta Crystallographica, Section B: Structural Science, Crystal Engineering and Materials (2019), 75(6), 933-941

Development and validation of a stability-indicating rp-hplc method for the determination of bendamustine in raw material and finished product
By Dhananjaya, G.; Naveen, M.; Pathi, P. Janaki; Raghuram, J.; Raju, N. Appala
From World Journal of Pharmaceutical Research (2018), 7(18), 1172-1187

Novel validated RP-HPLC method for bendamustine hydrochloride based on ion-pair chromatography: application in determining infusion stability and pharmacokinetics
By Singh, Yuvraj; Chandrashekar, Anumandla; Pawar, Vivek K.; Saravanakumar, Veeramuthu; Meher, Jayagopal; Raval, Kavit; Singh, Pankaj; Kumar, R. Dinesh; Chourasia, Manish K.
From Journal of Chromatographic Science (2017), 55(1), 30-39

Stability- indicating novel HPLC method for estimation of Bendamustine in pharmaceutical forms
By Reddy, Gade Srinivas; Reddy, S. L. N. Prasad; Reddy, L. Shiva kumar
From American Journal of PharmTech Research (2016), 6(2), 343-357

Bendamustine USP Related Compound G is chemically 4-[6-(2-Chloroethyl)-3,6,7,8-tetrahydro-3-methylimidazo[4,5-h][1,4]benzothiazin-2-yl]butanoic acid (as per USP) . Bendamustine USP Related Compound G is supplied with detailed characterization data compliant with regulatory guideline. Bendamustine USP Related Compound G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bendamustine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Bendamustine

SZ CAT No:	: SZ-B010007
CAS No	: 16506-27-7
Mol.F.	: C16H21Cl2N3O2
Mol.Wt.	: 358.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 3543-75-7 (HCl salt) ; 1374784-02-7 (hydrochloride hydrate)

Bendamustine Amino Isopropyl Ester Impurity

SZ CAT No:	: SZ-B010047
CAS No	: NA
Mol.F.	: C15H21N3O2 : HCl
Mol.Wt.	: 275.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1313020-26-6 (free base)

Bendamustine D8 Hydrochloride

SZ CAT No:	: SZ-B010D02
CAS No	: 1185068-23-8
Mol.F.	: C16H13D8Cl2N3O2 : HCl
Mol.Wt.	: 366.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1134803-33-0 (free base)

Bendamustine Deschloroethyl Acid Ethyl Ester

SZ CAT No:	: SZ-B010001
CAS No	: 2517968-40-8
Mol.F.	: C16H22ClN3O2
Mol.Wt.	: 323.8
Inv. Status	: In Stock

Bendamustine Dideschloroethyl Acid Impurity

SZ CAT No:	: SZ-B010003
CAS No	: 914626-62-3
Mol.F.	: C12H15N3O2
Mol.Wt.	: 233.3
Inv. Status	: In Stock
Rel. CAS No	: 1179363-38-2 (HCl salt)

Bendamustine Dimer 2'-Allyl Ester

SZ CAT No:	: SZ-B010019
CAS No	: NA
Mol.F.	: C35H45Cl3N6O4 : HCl
Mol.Wt.	: 720.2 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine USP Related Compound B

SZ CAT No:	: SZ-B010021
CAS No	: 2173004-95-8
Mol.F.	: C16H21N3O3 : HCl
Mol.Wt.	: 303.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1228552-02-0 (Free base)

Bendamustine Hydrochloride

SZ CAT No:	: SZ-B010000
CAS No	: 3543-75-7
Mol.F.	: C16H202N3O2 : HCl
Mol.Wt.	: 358.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 16506-27-7 (free base)

Bendamustine Impurity

SZ CAT No:	: SZ-B010015
CAS No	: NA
Mol.F.	: C32H43ClN6O6 : HCl
Mol.Wt.	: 643.2 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1219709-87-1 (free base)

Bendamustine Impurity 1

SZ CAT No:	: SZ-B010022
CAS No	: NA
Mol.F.	: C16H23N3O3 : HCl
Mol.Wt.	: 305.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1366085-72-4 (free base)

Bendamustine Impurity 10

SZ CAT No:	: SZ-B010031
CAS No	: NA
Mol.F.	: C12H15N3O5 : HCl
Mol.Wt.	: 281.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 91644-13-2 (free base)

Bendamustine Impurity 11

SZ CAT No:	: SZ-B010032
CAS No	: NA
Mol.F.	: C19H22N6O6 : HCl
Mol.Wt.	: 430.4 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 12

SZ CAT No:	: SZ-B010033
CAS No	: NA
Mol.F.	: C19H20N6O5 : HCl
Mol.Wt.	: 412.4 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 13

SZ CAT No:	: SZ-B010034
CAS No	: 914626-65-6
Mol.F.	: C19H18N6O4
Mol.Wt.	: 394.4
Inv. Status	: In Stock

Bendamustine Impurity 14

SZ CAT No:	: SZ-B010035
CAS No	: NA
Mol.F.	: C19H22N6 : HCl
Mol.Wt.	: 334.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 847588-86-7 (free base)

Bendamustine Impurity 15

SZ CAT No:	: SZ-B010036
CAS No	: 1469343-10-9
Mol.F.	: C15H21N2O2
Mol.Wt.	: 261.4
Inv. Status	: Custom Synthesis

Bendamustine Impurity 16

SZ CAT No:	: SZ-B010037
CAS No	: NA
Mol.F.	: C19H27Cl2N3O4
Mol.Wt.	: 432.3
Inv. Status	: In Stock

Bendamustine Impurity 17

SZ CAT No:	: SZ-B010038
CAS No	: NA
Mol.F.	: C18H24ClN3O4
Mol.Wt.	: 381.9
Inv. Status	: Out of Stock

Bendamustine Impurity 18

SZ CAT No:	: SZ-B010039
CAS No	: NA
Mol.F.	: C33H46N6O6 : HCl
Mol.Wt.	: 622.8 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 19

SZ CAT No:	: SZ-B010040
CAS No	: 3543-73-5
Mol.F.	: C14H19N3O2
Mol.Wt.	: 261.3
Inv. Status	: In Stock

Bendamustine Impurity 2

SZ CAT No:	: SZ-B010023
CAS No	: NA
Mol.F.	: C16H21Cl2N3O3 : HCl
Mol.Wt.	: 374.3 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 20

SZ CAT No:	: SZ-B010044
CAS No	: 2784-96-5
Mol.F.	: C7H9N3O2
Mol.Wt.	: 167.2
Inv. Status	: In Stock
Rel. CAS No	: 879649-75-9 (HCl salt)

Bendamustine Impurity 23

SZ CAT No:	: SZ-B010050
CAS No	: 7441-32-9
Mol.F.	: C30H24O12
Mol.Wt.	: 576.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 24

SZ CAT No:	: SZ-B010051
CAS No	: 88-26-6
Mol.F.	: C15H24O2
Mol.Wt.	: 236.4
Inv. Status	: Custom Synthesis

Bendamustine Impurity 25

SZ CAT No:	: SZ-B010052
CAS No	: NA
Mol.F.	: C16H19N3O2S2 : HCl
Mol.Wt.	: 349.5 : 36.5
Inv. Status	: In Stock

Bendamustine Impurity 26

SZ CAT No:	: SZ-B010069
CAS No	: 119548-63-9
Mol.F.	: C14H14N6O5
Mol.Wt.	: 346.3
Inv. Status	: Custom Synthesis

Bendamustine Impurity 27

SZ CAT No:	: SZ-B010070
CAS No	: NA
Mol.F.	: C15H18N6O4
Mol.Wt.	: 346.3
Inv. Status	: Custom Synthesis

Bendamustine Impurity 28

SZ CAT No:	: SZ-B010071
CAS No	: NA
Mol.F.	: C14H14N6O4
Mol.Wt.	: 330.3
Inv. Status	: Custom Synthesis

Bendamustine Impurity 29

SZ CAT No:	: SZ-B010072
CAS No	: NA
Mol.F.	: C15H16N6O2
Mol.Wt.	: 312.3
Inv. Status	: Custom Synthesis

Bendamustine Impurity 3

SZ CAT No:	: SZ-B010024
CAS No	: 60651-29-8
Mol.F.	: C7H11N3
Mol.Wt.	: 137.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1305319-65-6 (HCl salt)

Bendamustine Impurity 4 (Mixture of Isomers)

SZ CAT No:	: SZ-B010025
CAS No	: NA
Mol.F.	: C28H41Cl2N3O12 : HCl
Mol.Wt.	: 682.6 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 5

SZ CAT No:	: SZ-B010026
CAS No	: 1138238-08-0
Mol.F.	: C16H21Cl2N3O3
Mol.Wt.	: 374.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1258418-50-6 (HCl salt)

Bendamustine Impurity 6

SZ CAT No:	: SZ-B010027
CAS No	: NA
Mol.F.	: C32H42Cl2N6O5 : HCl
Mol.Wt.	: 661.6 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 7 (HCl)

SZ CAT No:	: SZ-B010028
CAS No	: NA
Mol.F.	: C15H19Cl2N3O3 : HCl
Mol.Wt.	: 360.3 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 8

SZ CAT No:	: SZ-B010029
CAS No	: NA
Mol.F.	: C18H26ClN3O3 : HCl
Mol.Wt.	: 367.9 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Impurity 9

SZ CAT No:	: SZ-B010030
CAS No	: NA
Mol.F.	: C32H43ClN6O6 : HCl
Mol.Wt.	: 643.2 : 36.5
Inv. Status	: Custom Synthesis

Bendamustine Isopropyl Ester

SZ CAT No:	: SZ-B010008
CAS No	: NA
Mol.F.	: C19H27Cl2N3O2 : HCl
Mol.Wt.	: 400.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1313020-25-5 (free base)

Bendamustine Methyl Ester (HCl)

SZ CAT No:	: SZ-B010009
CAS No	: NA
Mol.F.	: C17H23Cl2N3O2 : HCl
Mol.Wt.	: 372.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 109882-25-9 (free base)

Bendamustine Monohydroxy Acid Ethyl Ester

SZ CAT No:	: SZ-B010010
CAS No	: 898224-95-8
Mol.F.	: C18H26ClN3O3
Mol.Wt.	: 367.9
Inv. Status	: In Stock

Bendamustine Monohydroxy Isopropyl Ester Impurity

SZ CAT No:	: SZ-B010016
CAS No	: NA
Mol.F.	: C19H28ClN3O3 : HCl
Mol.Wt.	: 381.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1797008-41-3 (free base)

Bendamustine N-Desmethyl Impurity Hydrochloride

SZ CAT No:	: SZ-B010059
CAS No	: 31349-38-9
Mol.F.	: C15H19Cl2N3O2 : HCl
Mol.Wt.	: 344.2 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 41515-13-3 (free base)

Bendamustine Nitro Ethyl Ester Impurity

SZ CAT No:	: SZ-B010013
CAS No	: 3543-72-4
Mol.F.	: C14H17N3O4
Mol.Wt.	: 291.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1678557-24-8 (Sulfate salt)

Bendamustine PEG Ester Mixture

SZ CAT No:	: SZ-B010073
CAS No	: NA
Mol.F.	: NA
Mol.Wt.	: NA
Inv. Status	: Custom Synthesis

Bendamustine Propylene Glycol Ester 1

SZ CAT No:	: SZ-B010041
CAS No	: 1219709-88-2
Mol.F.	: C19H27Cl2N3O3
Mol.Wt.	: 416.3
Inv. Status	: Out of Stock

Bendamustine Propylene Glycol Ester 1 + 2

SZ CAT No:	: SZ-B010043
CAS No	: NA
Mol.F.	: C38H54Cl4N6O6
Mol.Wt.	: 832.7
Inv. Status	: Out of Stock

Bendamustine Propylene Glycol Ester 2

SZ CAT No:	: SZ-B010042
CAS No	: 1219709-89-3
Mol.F.	: C19H27Cl2N3O3
Mol.Wt.	: 416.3
Inv. Status	: Out of Stock

Bendamustine Trihydroxyethyl Dimer Impurity

SZ CAT No:	: SZ-B010014
CAS No	: NA
Mol.F.	: C32H44N6O7 : HCl
Mol.Wt.	: 624.7 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1391052-61-1 (free base)

Bendamustine USP Related Compound A

SZ CAT No:	: SZ-B010005
CAS No	: 109882-30-6
Mol.F.	: C16H23N3O4
Mol.Wt.	: 321.4
Inv. Status	: Limited Stock
Rel. CAS No	: 109882-29-3 (HCl salt)

Bendamustine USP Related Compound C

SZ CAT No:	: SZ-B010004
CAS No	: 3543-74-6
Mol.F.	: C18H27N3O4
Mol.Wt.	: 349.4
Inv. Status	: In Stock

Bendamustine USP Related Compound D (HCl salt)

SZ CAT No:	: SZ-B010002
CAS No	: 1797881-48-1
Mol.F.	: C14H18ClN3O2 : HCl
Mol.Wt.	: 295.8 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1219709-86-0 (free base)

Bendamustine USP Related Compound E (HCl)

SZ CAT No:	: SZ-B010011
CAS No	: 109882-26-0
Mol.F.	: C16H22ClN3O3 : HCl
Mol.Wt.	: 339.8 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 109882-27-1 (Free base)

Bendamustine USP Related Compound F

SZ CAT No:	: SZ-B010020
CAS No	: 1869075-89-7
Mol.F.	: C22H33Cl2N3O7
Mol.Wt.	: 522.4
Inv. Status	: In Stock
Rel. CAS No	: 1869075-90-0 (HCl salt)

Bendamustine USP Related Compound G

SZ CAT No:	: SZ-B010017
CAS No	: 191939-34-1
Mol.F.	: C16H20ClN3O2S
Mol.Wt.	: 353.9
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 2469039-29-8 (HCl salt)

Bendamustine USP Related Compound G Hydrochloride

SZ CAT No:	: SZ-B010061
CAS No	: 2469039-29-8
Mol.F.	: C16H20ClN3O2S : HCl
Mol.Wt.	: 353.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 191939-34-1 (free base)

Bendamustine USP Related Compound H

SZ CAT No:	: SZ-B010018
CAS No	: 1228551-91-4
Mol.F.	: C32H41Cl3N6O4
Mol.Wt.	: 680.1
Inv. Status	: In Stock
Rel. CAS No	: 1926162-37-9 (HCl salt)

Bendamustine USP Related Compound I (HCl)

SZ CAT No:	: SZ-B010006
CAS No	: NA
Mol.F.	: C18H25Cl2N3O2 : HCl
Mol.Wt.	: 386.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 87475-54-5 (free base)

Dihydroxy Bendamustine D3 Hydrochloride

SZ CAT No:	: SZ-B010D01
CAS No	: NA
Mol.F.	: C16H20D3N3O4 : HCl
Mol.Wt.	: 324.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1794737-33-9 (free base)

N-Nitroso Bendamustine Impurity

SZ CAT No:	: SZ-B010046
CAS No	: NA
Mol.F.	: C14H17ClN4O3
Mol.Wt.	: 324.8
Inv. Status	: In Stock

Bendamustine USP Related Compound G

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