Atracurium Impurity 9

SZ CAT No:	SZ-A021083
CAS No	1075726-89-4
Mol.F.	C25H34NO6
Mol.Wt.	444.5
Inv. Status	Custom Synthesis
Rel. CAS No	1075726-90-7 (benzenesulfonate salt) ; 1075726-86-1 (Iodide salt)

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Chemical Name: (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-(3-methoxy-3-oxopropyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(OC)CC[N+]1(C)[C@H](CC2=CC(OC)=C(OC)C=C2)C3=C(C=C(OC)C(OC)=C3)CC1

Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection
Agata Błazewicz, Zbigniew Fijałeka,b, Małgorzata Warowna-Grzeskiewicz ,Magdalena Jadach
Journal of Chromatography A, 1217 (2010) 1266–1272

Directly Coupled Chiral HPLC-NMR and HPLC-CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate
Nisha Mistry,Andrew D. Roberts, George E. Tranter,Peter Francis, Ian Barylski, Ismail M. Ismail,§ Jeremy K. Nicholson,| and John C. Lindon
Anal. Chem. 1999, 71, 2838-2843

Atracurium Impurity 9 is chemically (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-(3-methoxy-3-oxopropyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium. Atracurium Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Atracurium Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Atracurium.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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