Hydrochlorothiazide Impurity 18

SZ CAT No:	SZ-H006029
CAS No	NA
Mol.F.	C7H7ClN2O5S2
Mol.Wt.	298.7
Inv. Status	Custom Synthesis

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Chemical Name: 6-Chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonic acid 1,1-dioxide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=S(C1=C(Cl)C=C(C2=C1)NCNS2(=O)=O)(O)=O

Purification and identification of an impurity in bulk hydrochlorothiazide
xueguang fang,1 richard todd bibart,1 suzanne mayr,1 winnie yin,1 paul a. harmon,2 jennifer finnegan mccafferty,3 r. jeffrey tyrrell,4 robert a. reed
journal of pharmaceutical sciences, vol. 90, no. 11, november 2001

Simultaneous Determination of Hydrochlorothiazide and Benazepril Hydrochloride or Amiloride Hydrochloride in Presence of Hydrochlorothiazide Impurities: Chlorothiazide and Salamide by HPTLC Method
Ibrahim A. Naguib1, Eglal A. Abdelaleem1, Hala E. Zaazaa2 and Mohammed E. Draz
Journal of Chromatographic Science 2014;1–6

A Validated High-Performance Thin-Layer Chromatographic Method for the Simultaneous Determination of Zofenopril Calcium and Hydrochlorothiazide in the Presence of the Hydrochlorothiazide Impurities: Chlorothiazide and Salamide
Mamdouh R Rezk, Ahmed S Fayed, Hoda M Marzouk, Samah S Abbas
Journal of AOAC International, Volume 101, Issue 4, 1 July 2018, Pages 1031–1041

An improved validated HPLC method for separation of metoprolol and hydrochlorothiazide impurities in metoprolol and hydrochlorothiazide tablets
Avinash S. Patil1 , Shakil S. Sait2 , Abhijit Deshamukh1 and Girish Deshpande1
Der Pharmacia Lettre, 2015, 7 (2):183-190

Method Development and Validation for the Determination of Potential Impurities Present in Olmesartan Medoxomil and Hydrochlorothiazide in Fixed Dose Combination Drug Product by Using Reverse Phase – Ultra-Performance Liquid Chromatography Coupled with Diode-Array Detector
R. srikanth reddy,1 r. murali krishna,2 n. a. vekaria,1 sumathi v. rao,1 and bhaskara p. v. mantena1
Journal of Liquid Chromatography & Related Technologies, 38: 1343–1354, 2015

Hydrochlorothiazide Impurity 18 is chemically 6-Chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonic acid 1,1-dioxide. Hydrochlorothiazide Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Hydrochlorothiazide Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hydrochlorothiazide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Hydrochlorothiazide Impurity 18

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SZ CAT No:	: SZ-H006001
CAS No	: 58-93-5
Mol.F.	: C7H8ClN3O4S2
Mol.Wt.	: 297.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006002
CAS No	: 58-94-6
Mol.F.	: C7H6ClN3O4S2
Mol.Wt.	: 295.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006003
CAS No	: 121-30-2
Mol.F.	: C6H8ClN3O4S2
Mol.Wt.	: 285.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006004
CAS No	: 402824-96-8
Mol.F.	: C15H16Cl2N6O8S4
Mol.Wt.	: 607.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006005
CAS No	: 5233-42-1
Mol.F.	: C7H7Cl2N3O4S2
Mol.Wt.	: 332.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006D01
CAS No	: 1219798-89-6
Mol.F.	: C7H6D2ClN3O4S2
Mol.Wt.	: 299.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006006
CAS No	: 63779-86-2
Mol.F.	: C7H7ClN4O5S2
Mol.Wt.	: 326.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006D02
CAS No	: NA
Mol.F.	: C613CH6D2ClN15N2O4S2
Mol.Wt.	: 302.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006D03
CAS No	: NA
Mol.F.	: C7H5D2ClN4O5S2
Mol.Wt.	: 328.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-H006D04
CAS No	: NA
Mol.F.	: C613CH7ClN4O5S2
Mol.Wt.	: 327.7
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-H006007
CAS No	: 17277-91-7
Mol.F.	: C6H7ClN2O5S2
Mol.Wt.	: 286.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006008
CAS No	: NA
Mol.F.	: C6H7ClN2O5S2
Mol.Wt.	: 286.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006009
CAS No	: 1214-64-8
Mol.F.	: C6H5ClN4O4S2
Mol.Wt.	: 296.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006010
CAS No	: NA
Mol.F.	: C8H10N4O5S2
Mol.Wt.	: 306.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006D05
CAS No	: 1184995-49-0
Mol.F.	: C6H2D6ClN3O4S2
Mol.Wt.	: 291.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006011
CAS No	: NA
Mol.F.	: C15H15Cl2N7O9S4
Mol.Wt.	: 636.5
Inv. Status	: Inquire

SZ CAT No:	: SZ-H006012
CAS No	: NA
Mol.F.	: C7H6Cl2N4O5S2
Mol.Wt.	: 361.2
Inv. Status	: Inquire

SZ CAT No:	: SZ-H006013
CAS No	: 5790-69-2
Mol.F.	: C6H7ClN2O2S
Mol.Wt.	: 206.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006014
CAS No	: 957785-35-2
Mol.F.	: C6H5ClN2O4S
Mol.Wt.	: 236.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006015
CAS No	: 69031-67-0
Mol.F.	: C6H7N3O6S2
Mol.Wt.	: 281.3
Inv. Status	: Custom Synthesis

Hydrochlorothiazide Impurity 18

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SZ CAT No:	: SZ-H006016
CAS No	: NA
Mol.F.	: C6H6ClN3O6S2
Mol.Wt.	: 315.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006017
CAS No	: 19477-32-8
Mol.F.	: C7H7ClN2O2S
Mol.Wt.	: 218.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006018
CAS No	: 1083-36-9
Mol.F.	: C6H8ClN3O4S2
Mol.Wt.	: 285.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006019
CAS No	: 40642-90-8
Mol.F.	: C6H9N3O4S2
Mol.Wt.	: 251.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006020
CAS No	: 5250-72-6
Mol.F.	: C6H7Cl2N3O4S2
Mol.Wt.	: 320.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006021
CAS No	: 856302-12-0
Mol.F.	: C7H8ClN3O4S2
Mol.Wt.	: 297.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006022
CAS No	: 23141-82-4
Mol.F.	: C7H9N3O4S2
Mol.Wt.	: 263.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006023
CAS No	: NA
Mol.F.	: C7H5Cl2N5O6S2
Mol.Wt.	: 390.2
Inv. Status	: Inquire

SZ CAT No:	: SZ-H006024
CAS No	: 4140-83-4
Mol.F.	: C6H7ClN2O2S
Mol.Wt.	: 206.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-H006025
CAS No	: 1954-94-5
Mol.F.	: C6H7ClN2O2S
Mol.Wt.	: 206.6
Inv. Status	: Custom Synthesis