Febuxostat D9

SZ CAT No:	SZ-F010D02
CAS No	1246819-50-0
Mol.F.	C16H7D9N2O3S
Mol.Wt.	325.4
Inv. Status	Custom Synthesis

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Chemical Name: 2-(3-Cyano-4-(2-(methyl-d3)propoxy-1,1,2,3,3,3-d6)phenyl)-4-methylthiazole-5-carboxylic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC(C(SC(C1=CC(C#N)=C(OC([2H])([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1)=N2)=C2C)=O

HPTLC and Spectrophotometric Estimation of Febuxostat and Diclofenac Potassium in Their Combined Tablets
Fawzi A. El-Yazbi, Omayma A. Amin, Eman I. El-Kimary, Essam F. Khamis, Sameh E. Younis
Journal of Chromatographic Science, Volume 54, Issue 7, 1 August 2016, Pages 1146–1152

Study of impurity carryover and impurity profile in Febuxostat drug substance by LC-MS/MS technique
Mustakhusen H. Kadivar a, Praveen Kumar Sinhaa, Dharmendra Kushwaha,∗, Pijush Janaa,∗, Hitesh Sharmaa, Atul Bapodra
Journal of Pharmaceutical and Biomedical Analysis 56 (2011) 749–757

Development and Validation of a Stability-Indicating RP-HPLC Method for the Determination of Febuxostat (a Xanthine Oxidase Inhibitor)
Mathrusri Annapurna Mukthinuthalapati, Sai Pavan Kumar Bandaru, Venkatesh Bukkapatnam, Chitaranjan Mohapatro
Journal of Chromatographic Science, Volume 51, Issue 10, November/December 2013, Pages 931–938

Simple and Rapid Micellar Electrokinetic Chromatography Method for Simultaneous Determination of Febuxostat and its Related Impurities
Miranda Sertić1 · Ana Mornar1 · Biljana Nigović
Chromatographia volume 83, pages993–1000(2020)

Febuxostat D9 is chemically 2-(3-Cyano-4-(2-(methyl-d3)propoxy-1,1,2,3,3,3-d6)phenyl)-4-methylthiazole-5-carboxylic acid. Febuxostat D9 is supplied with detailed characterization data compliant with regulatory guideline. Febuxostat D9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Febuxostat.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Febuxostat USP Related Compound C

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Febuxostat

SZ CAT No:	: SZ-F010001
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Febuxostat Acyl-Β-D-Glucuronide

SZ CAT No:	: SZ-F010004
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Mol.F.	: C22H24N2O9S
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Febuxostat Amide Impurity

SZ CAT No:	: SZ-F010005
CAS No	: 1239233-86-3
Mol.F.	: C16H18N2O4S
Mol.Wt.	: 334.4
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Febuxostat Bromo Impurity

SZ CAT No:	: SZ-F010006
CAS No	: 144060-40-2
Mol.F.	: C15H16BrNO3S
Mol.Wt.	: 370.3
Inv. Status	: In Stock

Febuxostat Butyl Ether Analog

SZ CAT No:	: SZ-F010007
CAS No	: 1657014-33-9
Mol.F.	: C16H16N2O3S
Mol.Wt.	: 316.4
Inv. Status	: In Stock

Febuxostat Descarboxy Impurity

SZ CAT No:	: SZ-F010008
CAS No	: 1335202-60-2
Mol.F.	: C15H16N2OS
Mol.Wt.	: 272.4
Inv. Status	: Custom Synthesis

Febuxostat Descyano Ethyl Ester

SZ CAT No:	: SZ-F010009
CAS No	: 144060-97-9
Mol.F.	: C17H21NO3S
Mol.Wt.	: 319.4
Inv. Status	: In Stock

Febuxostat Descyano Hydroxy Ethyl Ester

SZ CAT No:	: SZ-F010010
CAS No	: 161797-99-5
Mol.F.	: C13H13NO3S
Mol.Wt.	: 263.3
Inv. Status	: In Stock

Febuxostat Descyano Hydroxy Impurity

SZ CAT No:	: SZ-F010011
CAS No	: 886501-78-6
Mol.F.	: C11H9NO3S
Mol.Wt.	: 235.3
Inv. Status	: Custom Synthesis

Febuxostat Descyano Impurity

SZ CAT No:	: SZ-F010012
CAS No	: 1206550-99-3
Mol.F.	: C15H17NO3S
Mol.Wt.	: 291.4
Inv. Status	: In Stock

Febuxostat Dicarboxylic Acid Impurity

SZ CAT No:	: SZ-F010013
CAS No	: 1239233-87-4
Mol.F.	: C16H17NO5S
Mol.Wt.	: 335.4
Inv. Status	: In Stock

Febuxostat Dimethylthiazole Ethyl Ester Impurity

SZ CAT No:	: SZ-F010014
CAS No	: 7210-77-7
Mol.F.	: C8H11NO2S
Mol.Wt.	: 185.2
Inv. Status	: Custom Synthesis

Febuxostat Dithiazole Acid Impurity

SZ CAT No:	: SZ-F010015
CAS No	: 1330632-48-8
Mol.F.	: C20H20N2O5S2
Mol.Wt.	: 432.5
Inv. Status	: Custom Synthesis

Febuxostat Ethyl Ester

SZ CAT No:	: SZ-F010016
CAS No	: 160844-75-7
Mol.F.	: C18H20N2O3S
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Febuxostat Isopropyl Ester

SZ CAT No:	: SZ-F010017
CAS No	: 1346238-10-5
Mol.F.	: C19H22N2O3S
Mol.Wt.	: 358.5
Inv. Status	: In Stock

Febuxostat Isopropyl Ether Analog

SZ CAT No:	: SZ-F010018
CAS No	: 144060-52-6
Mol.F.	: C15H14N2O3S
Mol.Wt.	: 302.4
Inv. Status	: In Stock

Febuxostat Methyl Ester

SZ CAT No:	: SZ-F010019
CAS No	: 923942-34-1
Mol.F.	: C17H18N2O3S
Mol.Wt.	: 330.4
Inv. Status	: In Stock

Febuxostat USP Related Compound E

SZ CAT No:	: SZ-F010020
CAS No	: 1530308-87-2
Mol.F.	: C15H14N2O3S
Mol.Wt.	: 302.4
Inv. Status	: In Stock

Febuxostat USP Related Compound D

SZ CAT No:	: SZ-F010021
CAS No	: 1335202-59-9
Mol.F.	: C16H16N2O3S
Mol.Wt.	: 316.0
Inv. Status	: In Stock

Febuxostat Tert-butoxy Acid

SZ CAT No:	: SZ-F010022
CAS No	: 2418591-43-0
Mol.F.	: C16H16N2O3S
Mol.Wt.	: 316.4
Inv. Status	: In Stock

Febuxostat Dithioamide Impurity

SZ CAT No:	: SZ-F010023
CAS No	: 1330632-46-6
Mol.F.	: C12H16N2OS2
Mol.Wt.	: 268.4
Inv. Status	: In Stock

Febuxostat Impurity 3

SZ CAT No:	: SZ-F010024
CAS No	: 1330632-47-7
Mol.F.	: C22H24N2O5S2
Mol.Wt.	: 460.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 1

SZ CAT No:	: SZ-F010025
CAS No	: 161798-01-2
Mol.F.	: C14H13NO4S
Mol.Wt.	: 291.3
Inv. Status	: In Stock

Febuxostat Impurity 2

SZ CAT No:	: SZ-F010026
CAS No	: 161798-03-4
Mol.F.	: C18H21NO4S
Mol.Wt.	: 347.4
Inv. Status	: In Stock

Febuxostat Impurity 6

SZ CAT No:	: SZ-F010027
CAS No	: 1271738-74-9
Mol.F.	: C18H22N2O4S
Mol.Wt.	: 362.5
Inv. Status	: In Stock

Febuxostat Impurity 7

SZ CAT No:	: SZ-F010028
CAS No	: NA
Mol.F.	: C16H18N2O4S
Mol.Wt.	: 334.4
Inv. Status	: In Stock

3-Descyano-3-formyl Febuxostat

SZ CAT No:	: SZ-F010029
CAS No	: 144060-62-8
Mol.F.	: C16H17NO4S
Mol.Wt.	: 319.4
Inv. Status	: In Stock

Febuxostat Impurity 10

SZ CAT No:	: SZ-F010030
CAS No	: NA
Mol.F.	: C16H16N2O4S
Mol.Wt.	: 332.4
Inv. Status	: Custom Synthesis

4-Nitrophthalonitrile

SZ CAT No:	: SZ-F010031
CAS No	: 31643-49-9
Mol.F.	: C8H3N3O2
Mol.Wt.	: 173.1
Inv. Status	: Custom Synthesis

Febuxostat Impurity 12

SZ CAT No:	: SZ-F010032
CAS No	: NA
Mol.F.	: C9H2N4O2
Mol.Wt.	: 198.1
Inv. Status	: Custom Synthesis

Febuxostat Impurity 13

SZ CAT No:	: SZ-F010033
CAS No	: NA
Mol.F.	: C32H36N4O6S2
Mol.Wt.	: 636.8
Inv. Status	: Custom Synthesis

Febuxostat Impurity 15

SZ CAT No:	: SZ-F010034
CAS No	: NA
Mol.F.	: C15H14N2O3S
Mol.Wt.	: 302.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 16

SZ CAT No:	: SZ-F010035
CAS No	: NA
Mol.F.	: C15H14N2O3S
Mol.Wt.	: 302.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 17

SZ CAT No:	: SZ-F010036
CAS No	: NA
Mol.F.	: C14H12N2O3S
Mol.Wt.	: 288.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 18

SZ CAT No:	: SZ-F010037
CAS No	: NA
Mol.F.	: C15H15NO4
Mol.Wt.	: 273.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 19

SZ CAT No:	: SZ-F010038
CAS No	: 2375033-35-3
Mol.F.	: C18H20N2O3S
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Febuxostat Butyl Ester Impurity

SZ CAT No:	: SZ-F010039
CAS No	: 1619982-02-3
Mol.F.	: C20H24N2O3S
Mol.Wt.	: 372.5
Inv. Status	: In Stock

3-Cyano-4-isobutoxybenzothioamide

SZ CAT No:	: SZ-F010040
CAS No	: 163597-57-7
Mol.F.	: C12H14N2OS
Mol.Wt.	: 234.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 21

SZ CAT No:	: SZ-F010041
CAS No	: 1346238-12-7
Mol.F.	: C16H14N2O3S
Mol.Wt.	: 314.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 22

SZ CAT No:	: SZ-F010042
CAS No	: NA
Mol.F.	: C16H16N2O3S
Mol.Wt.	: 316.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 23

SZ CAT No:	: SZ-F010043
CAS No	: NA
Mol.F.	: C22H24N2O5S2
Mol.Wt.	: 460.6
Inv. Status	: Custom Synthesis

Febuxostat Impurity 24

SZ CAT No:	: SZ-F010044
CAS No	: 2428631-65-4
Mol.F.	: C17H15N3O3S
Mol.Wt.	: 341.4
Inv. Status	: Custom Synthesis

Febuxostat Amide Methyl Ester

SZ CAT No:	: SZ-F010045
CAS No	: 1643131-89-8
Mol.F.	: C17H20N2O4S
Mol.Wt.	: 348.4
Inv. Status	: Custom Synthesis

Febuxostat D7

SZ CAT No:	: SZ-F010D01
CAS No	: 1285539-74-3
Mol.F.	: C16H9D7N2O3S
Mol.Wt.	: 323.4
Inv. Status	: Custom Synthesis

Febuxostat D9

SZ CAT No:	: SZ-F010D02
CAS No	: 1246819-50-0
Mol.F.	: C16H7D9N2O3S
Mol.Wt.	: 325.4
Inv. Status	: Custom Synthesis

3-Descyano 3-Bromo-Febuxostat D9

SZ CAT No:	: SZ-F010D03
CAS No	: NA
Mol.F.	: C15H7D9BrNO3S
Mol.Wt.	: 379.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 144060-40-2 (Unlabeled)

3-Descyano Febuxostat D9 Ethyl Ester

SZ CAT No:	: SZ-F010D04
CAS No	: NA
Mol.F.	: C17H12D9NO3S
Mol.Wt.	: 328.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 144060-97-9 (Unlabeled)

Febuxostat Impurity 26

SZ CAT No:	: SZ-F010048
CAS No	: 2230270-05-8
Mol.F.	: C18H20N2O3S
Mol.Wt.	: 344.4
Inv. Status	: In Stock

3-Descyano-3-ethoxycarbonyl Febuxostat

SZ CAT No:	: SZ-F010049
CAS No	: 2476465-11-7
Mol.F.	: C18H21NO5S
Mol.Wt.	: 363.4
Inv. Status	: In Stock

Febuxostat Diformyl Impurity

SZ CAT No:	: SZ-F010050
CAS No	: 2073891-59-3
Mol.F.	: C15H13NO5S
Mol.Wt.	: 319.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 27

SZ CAT No:	: SZ-F010051
CAS No	: NA
Mol.F.	: C32H31N3O6S2
Mol.Wt.	: 617.7
Inv. Status	: Custom Synthesis

Febuxostat Impurity 28

SZ CAT No:	: SZ-F010052
CAS No	: 1350352-70-3
Mol.F.	: C16H18N2O4S
Mol.Wt.	: 334.4
Inv. Status	: In Stock

Febuxostat Impurity 29

SZ CAT No:	: SZ-F010053
CAS No	: NA
Mol.F.	: C12H7ClN2O2S
Mol.Wt.	: 278.7
Inv. Status	: Custom Synthesis

Ethyl 2,2-dichloro-3-Oxobutanoate

SZ CAT No:	: SZ-F010054
CAS No	: 6134-66-3
Mol.F.	: C6H8Cl2O3
Mol.Wt.	: 199
Inv. Status	: In Stock

3-Hydroxybenzothioamide

SZ CAT No:	: SZ-F010055
CAS No	: 104317-54-6
Mol.F.	: C7H7NOS
Mol.Wt.	: 153.2
Inv. Status	: Custom Synthesis

2-Hydroxybenzothioamide

SZ CAT No:	: SZ-F010056
CAS No	: 7133-90-6
Mol.F.	: C7H7NOS
Mol.Wt.	: 153.2
Inv. Status	: Custom Synthesis

Isopropyloxycarbonyl Febuxostat

SZ CAT No:	: SZ-F010057
CAS No	: NA
Mol.F.	: C19H23NO5S
Mol.Wt.	: 377.5
Inv. Status	: Custom Synthesis

Febuxostat Ethyl Ester Amide Impurity

SZ CAT No:	: SZ-F010058
CAS No	: 1346238-15-0
Mol.F.	: C18H22N2O4S
Mol.Wt.	: 362.4
Inv. Status	: Custom Synthesis

Febuxostat Isobutyl Ester Impurity

SZ CAT No:	: SZ-F010059
CAS No	: NA
Mol.F.	: C21H28N2O4S
Mol.Wt.	: 404.5
Inv. Status	: Custom Synthesis

Febuxostat Impurity 30

SZ CAT No:	: SZ-F010060
CAS No	: 2230270-03-6
Mol.F.	: C18H21NO4S
Mol.Wt.	: 347.4
Inv. Status	: Custom Synthesis

Febuxostat DEE Impurity

SZ CAT No:	: SZ-F010061
CAS No	: 1643131-93-4
Mol.F.	: C20H25NO5S
Mol.Wt.	: 391.5
Inv. Status	: Custom Synthesis

Ethyl 2-Chloracetoacetate

SZ CAT No:	: SZ-F010062
CAS No	: 609-15-4
Mol.F.	: C6H9ClO3
Mol.Wt.	: 164.6
Inv. Status	: In Stock

4-Hydroxybenzothioamide

SZ CAT No:	: SZ-F010063
CAS No	: 25984-63-8
Mol.F.	: C7H7NOS
Mol.Wt.	: 153.2
Inv. Status	: Custom Synthesis

Febuxostat Impurity 31

SZ CAT No:	: SZ-F010064
CAS No	: 138330-01-5
Mol.F.	: C10H9NOS
Mol.Wt.	: 191.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 29302-63-4 (HCl salt) ; 1172835-03-8 (HBr salt)

3-Descyano Febuxostat D9

SZ CAT No:	: SZ-F010D05
CAS No	: NA
Mol.F.	: C15H8D9NO3S
Mol.Wt.	: 300.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 32

SZ CAT No:	: SZ-F010065
CAS No	: NA
Mol.F.	: C17H18N2O3S
Mol.Wt.	: 330.4
Inv. Status	: Custom Synthesis

Febuxostat Impurity 33

SZ CAT No:	: SZ-F010066
CAS No	: 1312815-35-2
Mol.F.	: C12H9NO4S
Mol.Wt.	: 263.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 34

SZ CAT No:	: SZ-F010067
CAS No	: NA
Mol.F.	: C14H13NO4S
Mol.Wt.	: 291.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 35

SZ CAT No:	: SZ-F010068
CAS No	: NA
Mol.F.	: C14H13NO4S
Mol.Wt.	: 291.3
Inv. Status	: Custom Synthesis

Febuxostat Impurity 36

SZ CAT No:	: SZ-F010069
CAS No	: NA
Mol.F.	: C14H13NO4S
Mol.Wt.	: 291.3
Inv. Status	: Custom Synthesis

Febuxostat D9

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