Tenofovir Alafenamide D6

SZ CAT No:	SZ-T012D02
CAS No	NA
Mol.F.	C21H23D6N6O5P
Mol.Wt.	482.5
Inv. Status	Custom Synthesis

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: Propan-2-yl-1,1,1,3,3,3-d6 ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: NC1=C2C(N(C[C@@H](C)OC[P@@](N[C@@H](C)C(OC(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC3=CC=CC=C3)=O)C=N2)=NC=N1

Stability indicating RP-HPLC method development and validation for the simultaneous estimation of darunavir, cobicistat, emtricitabine and tenofovir alafenamide in bulk and pharmaceutical formulation
By Parameswari, S. Angala; Ankinapalli, Ajay Kumar Reddy; Tsegaye, Tesfaye; Alagusundaram, M.
From International Journal of Pharmaceutical Sciences and Research (2021), 12(6), 3216-3224

Stability-indicating high-performance thin-layer chromatography method for the simultaneous estimation of emtricitabine and tenofovir alafenamide fumarate
By Kashid, Arun M.; Kadam, Rohini R.
From Journal of Planar Chromatography--Modern TLC (2021), Ahead of Print

Method development and validation for multi-component analysis of lamivudine & tenofovir disoproxil fumarate in bulk drug by UV-visible spectrophotometer & RP-HPLC
By Sharma, Shweta; Ankalgi, Amar Deep; Kaushal, Pooja; Ashawat, M. S.
From Journal of Applied Pharmaceutical Research (2020), 8(4), 70-76

Tenofovir Alafenamide D6 is chemically Propan-2-yl-1,1,1,3,3,3-d6 ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate. Tenofovir Alafenamide D6 is supplied with detailed characterization data compliant with regulatory guideline. Tenofovir Alafenamide D6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tenofovir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Tenofovir Disoproxil Desmethyl Fumarate

SZ CAT No:	: SZ-T012011
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Mol.F.	: C22H32N5O14P
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Tenofovir Disoproxil Dimer

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Tenofovir Disoproxil Fumarate

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Mol.F.	: C19H30N5O10P : C4H4O4
Mol.Wt.	: 519.4 : 116.1
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Tenofovir Ethanol Impurity

SZ CAT No:	: SZ-T012014
CAS No	: 707-99-3
Mol.F.	: C7H9N5O
Mol.Wt.	: 179.2
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Tenofovir Disoproxil Fumarate IP Impurity D

SZ CAT No:	: SZ-T012015
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Mol.F.	: C14H22N5O7P
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Tenofovir Alafenamide Fumarate

SZ CAT No:	: SZ-T012016
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Mol.F.	: C21H29N6O5P : C4H4O4
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Tenofovir Disoproxil Maleate

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Mol.F.	: C19H30N5O10P : C4H4O4
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Tenofovir Disoproxil USP Related Compound G

SZ CAT No:	: SZ-T012018
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Mol.F.	: C17H28N5O7P : C4H4O4
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Tenofovir Disoproxil Related Compound F

SZ CAT No:	: SZ-T012019
CAS No	: 1422284-17-0
Mol.F.	: C18H28N5O10P : C4H4O4
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Tenofovir monophosphate

SZ CAT No:	: SZ-T012020
CAS No	: 206646-04-0
Mol.F.	: C9H15N5O7P2
Mol.Wt.	: 367.2
Inv. Status	: Custom Synthesis

Tenofovir Diphosphate

SZ CAT No:	: SZ-T012021
CAS No	: 166403-66-3
Mol.F.	: C9H16N5O10P3
Mol.Wt.	: 447.2
Inv. Status	: Custom Synthesis

Tenofovir Disoproxil Carbamate (Related Compound H)

SZ CAT No:	: SZ-T012022
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Mol.F.	: C23H36N5O12P
Mol.Wt.	: 605.5
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Desmethyl Tenofovir Disoproxoil

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Mol.F.	: C18H28N5O10P
Mol.Wt.	: 505.4
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Tenofovir Disoproxil Fumarate IP Impurity L

SZ CAT No:	: SZ-T012024
CAS No	: NA
Mol.F.	: C18H29N6O9P : C4H4O4
Mol.Wt.	: 504.4 : 116.1
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Diisopropyl Tenofovir Fumarate

SZ CAT No:	: SZ-T012025
CAS No	: NA
Mol.F.	: C15H26N5O4P : C4H4O4
Mol.Wt.	: 371.4 : 116.1
Inv. Status	: In Stock

Diethylaminocarboxymethyl POC Tenofovir Fumarate

SZ CAT No:	: SZ-T012026
CAS No	: 2820170-87-2
Mol.F.	: C20H33N6O9P : C4H4O4
Mol.Wt.	: 532.5 : 116.1
Inv. Status	: Limited Stock

Mono-POC Methyl Tenofovir Fumarate (Mixture of Diastereomers)

SZ CAT No:	: SZ-T012027
CAS No	: NA
Mol.F.	: C15H24N5O7P : C4H4O4
Mol.Wt.	: 417.4 : 116.1
Inv. Status	: In Stock

Mono-POC Tenofovir Fumarate Salt

SZ CAT No:	: SZ-T012028
CAS No	: NA
Mol.F.	: C17H26N5O10P : C4H4O4
Mol.Wt.	: 491.4 : 116.1
Inv. Status	: In Stock

6N-Hydroxymethyl Tenofovir Disoproxil

SZ CAT No:	: SZ-T012029
CAS No	: 1244022-53-4
Mol.F.	: C20H32N5O11P
Mol.Wt.	: 549.5
Inv. Status	: Under Synthesis

Tenofovir Disoproxil Fumarate IP Impurity E

SZ CAT No:	: SZ-T012030
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Mol.F.	: C18H28N5O9P
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SZ CAT No:	: SZ-T012031
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Mol.Wt.	: 315.3
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CAS No	: 1346597-36-1
Mol.F.	: C12H20N5O4P
Mol.Wt.	: 329.3
Inv. Status	: In Stock

n-POC-POC Tenofovir Fumarate

SZ CAT No:	: SZ-T012033
CAS No	: NA
Mol.F.	: C19H30N5O10P : C4H4O4
Mol.Wt.	: 519.4 : 116.1
Inv. Status	: In Stock

Mono-POC Ethyl Tenofovir

SZ CAT No:	: SZ-T012035
CAS No	: 1796539-92-8
Mol.F.	: C16H26N5O7P
Mol.Wt.	: 431.4
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Tenofovir Alafenamide Hemifumarate

SZ CAT No:	: SZ-T012036
CAS No	: 1392275-56-7
Mol.F.	: C21H29N6O5P : 1/2(C4H4O4)
Mol.Wt.	: 476.5 : 1/2(116.1)
Inv. Status	: In Stock

rac-Tenofovir Disoproxil Related Compound G Fumarate

SZ CAT No:	: SZ-T012037
CAS No	: NA
Mol.F.	: C17H28N5O7P : C4H4O4
Mol.Wt.	: 445.4 : 116.1
Inv. Status	: Custom Synthesis

Tenofovir Disoproxil Fumarate Impurity(N6-CH2OH-POC PMPA)

SZ CAT No:	: SZ-T012038
CAS No	: 1244022-55-6
Mol.F.	: C15H24N5O8P
Mol.Wt.	: 433.4
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Tenofovir Related Compound 1

SZ CAT No:	: SZ-T012039
CAS No	: 342631-41-8
Mol.F.	: C21H22N5O4P
Mol.Wt.	: 439.4
Inv. Status	: In Stock

Monophenyl Tenofovir

SZ CAT No:	: SZ-T012040
CAS No	: 379270-35-6
Mol.F.	: C15H18N5O4P
Mol.Wt.	: 363.3
Inv. Status	: In Stock

Tenofovir Related Compound 3

SZ CAT No:	: SZ-T012041
CAS No	: 52364-31-5
Mol.F.	: C13H13O4P
Mol.Wt.	: 264.2
Inv. Status	: Custom Synthesis

Tenofovir Related Compound 4

SZ CAT No:	: SZ-T012042
CAS No	: 851456-00-3
Mol.F.	: C15H25N6O5P
Mol.Wt.	: 400.4
Inv. Status	: In Stock

Tenofovir Related Compound 6 (RRS)

SZ CAT No:	: SZ-T012043
CAS No	: NA
Mol.F.	: C21H29N6O5P : C4H6O6
Mol.Wt.	: 476.5 : 150.1
Inv. Status	: In Stock

Tenofovir Related Compound 7

SZ CAT No:	: SZ-T012044
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Mol.F.	: C6H13NO2
Mol.Wt.	: 131.2
Inv. Status	: In Stock

Tenofovir Related Compound 8

SZ CAT No:	: SZ-T012045
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Mol.F.	: C21H36N7O6P
Mol.Wt.	: 513.5
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Tenofovir Related Compound 10

SZ CAT No:	: SZ-T012046
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Mol.F.	: C9H13N5
Mol.Wt.	: 191.2
Inv. Status	: In Stock

Tenofovir Related Compound 12

SZ CAT No:	: SZ-T012047
CAS No	: NA
Mol.F.	: C23H31N8O11PS
Mol.Wt.	: 658.6
Inv. Status	: Custom Synthesis

Tenofovir Related Compound 14

SZ CAT No:	: SZ-T012048
CAS No	: 1244022-52-3
Mol.F.	: C8H11N5O
Mol.Wt.	: 193.2
Inv. Status	: Custom Synthesis

Tenofovir Related Compound 15

SZ CAT No:	: SZ-T012049
CAS No	: 1796539-83-7
Mol.F.	: C10H16N5O4P
Mol.Wt.	: 301.2
Inv. Status	: In Stock

Tenofovir Dimer Sodium Salt

SZ CAT No:	: SZ-T012050
CAS No	: NA
Mol.F.	: C18H24N10O7P2 : 2(Na)
Mol.Wt.	: 554.4 : 2(23.0)
Inv. Status	: In Stock

Tri-POC Tenofovir Dimer

SZ CAT No:	: SZ-T012051
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Mol.F.	: C34H52N10O17P2
Mol.Wt.	: 934.8
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Tenofovir Mono POC Dimer

SZ CAT No:	: SZ-T012052
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Mol.F.	: C29H44N10O14P2
Mol.Wt.	: 818.7
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Tenofovir Trimer Impurity 1

SZ CAT No:	: SZ-T012053
CAS No	: NA
Mol.F.	: C55H82N15O27P3
Mol.Wt.	: 1478.3
Inv. Status	: Custom Synthesis

Tenofovir Trimer Impurity 2

SZ CAT No:	: SZ-T012054
CAS No	: NA
Mol.F.	: C50H74N15O24P3
Mol.Wt.	: 1362.2
Inv. Status	: Custom Synthesis

Tenofovir Trimer Impurity 3

SZ CAT No:	: SZ-T012055
CAS No	: NA
Mol.F.	: C60H90N15O30P3
Mol.Wt.	: 1594.4
Inv. Status	: Custom Synthesis

Tenofovir Impurity 1

SZ CAT No:	: SZ-T012056
CAS No	: NA
Mol.F.	: C21H36N7O6P : C4H4O4
Mol.Wt.	: 513.5 : 116.1
Inv. Status	: In Stock

Tenofovir Adenine impurity

SZ CAT No:	: SZ-T012057
CAS No	: 73-24-5
Mol.F.	: C5H5N5
Mol.Wt.	: 135.1
Inv. Status	: In Stock

Tenofovir 9-Propenyl Impurity

SZ CAT No:	: SZ-T012058
CAS No	: 4121-39-5
Mol.F.	: C8H9N5
Mol.Wt.	: 175.2
Inv. Status	: In Stock

Tenofovir Impurity 35

SZ CAT No:	: SZ-T012059
CAS No	: 1962114-91-5
Mol.F.	: C15H22N5O7P
Mol.Wt.	: 415.3
Inv. Status	: Custom Synthesis

Tenofovir Impurity 36 (RSR)

SZ CAT No:	: SZ-T012060
CAS No	: NA
Mol.F.	: C21H29N6O5P : C4H6O6
Mol.Wt.	: 476.5 : 150.1
Inv. Status	: In Stock

Tenofovir Impurity 37

SZ CAT No:	: SZ-T012061
CAS No	: 342631-31-6
Mol.F.	: C19H25N6O5P
Mol.Wt.	: 448.4
Inv. Status	: In Stock

Ethyl Impurity

SZ CAT No:	: SZ-T012062
CAS No	: NA
Mol.F.	: C16H26N5O7P : C4H4O4
Mol.Wt.	: 431.4 : 116.1
Inv. Status	: Limited Stock

Tenofovir Mono ester Impurity

SZ CAT No:	: SZ-T012063
CAS No	: 1534434-02-0
Mol.F.	: C14H22N5O7P : C4H4O4
Mol.Wt.	: 403.3 : 116.1
Inv. Status	: In Stock

Tenofovir Alafenamide Enantiomer (SRR)

SZ CAT No:	: SZ-T012064
CAS No	: NA
Mol.F.	: C21H29N6O5P : C4H6O6
Mol.Wt.	: 476.5 : 150.1
Inv. Status	: In Stock

Tenofovir D6

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Mol.F.	: C9H8D6N5O4P
Mol.Wt.	: 293.3
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide O-Desphenyl Impurity

SZ CAT No:	: SZ-T012065
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Mol.Wt.	: 400.4
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Tenofovir Disoproxil Fumarate USP RC J

SZ CAT No:	: SZ-T012066
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Mol.F.	: C21H34N5O9P
Mol.Wt.	: 531.5
Inv. Status	: In Stock

Tenofovir Impurity 38

SZ CAT No:	: SZ-T012067
CAS No	: NA
Mol.F.	: C21H29N6O5P
Mol.Wt.	: 476.5
Inv. Status	: Custom Synthesis

Tenofovir Impurity 39 (RRR)

SZ CAT No:	: SZ-T012068
CAS No	: NA
Mol.F.	: C21H29N6O5P : C4H6O6
Mol.Wt.	: 476.5 : 150.1
Inv. Status	: In Stock

Tenofovir Impurity 40 (SSS)

SZ CAT No:	: SZ-T012069
CAS No	: NA
Mol.F.	: C21H29N6O5P
Mol.Wt.	: 476.5
Inv. Status	: In Stock

Tenofovir Impurity 41 (SRS)

SZ CAT No:	: SZ-T012070
CAS No	: NA
Mol.F.	: C21H29N6O5P : C4H6O6
Mol.Wt.	: 476.5 : 150.1
Inv. Status	: In Stock

Tenofovir Impurity 47

SZ CAT No:	: SZ-T012076
CAS No	: NA
Mol.F.	: C29H42FN8O12PS
Mol.Wt.	: 776.7
Inv. Status	: Custom Synthesis

Iso-Propyl p-Toluenesulfonate

SZ CAT No:	: SZ-T012077
CAS No	: 2307-69-9
Mol.F.	: C10H14O3S
Mol.Wt.	: 214.3
Inv. Status	: In Stock

Tenofovir Disoproxil T5 Impurity

SZ CAT No:	: SZ-T012078
CAS No	: NA
Mol.F.	: C19H28N10O8P2
Mol.Wt.	: 586.4
Inv. Status	: Custom Synthesis

Tenofovir Disoproxil T7 Impurity

SZ CAT No:	: SZ-T012079
CAS No	: NA
Mol.F.	: C15H22N5O7P
Mol.Wt.	: 415.3
Inv. Status	: Custom Synthesis

Tenofovir Impurity 86

SZ CAT No:	: SZ-T012081
CAS No	: NA
Mol.F.	: C34H52N10O17P2
Mol.Wt.	: 934.8
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide Imine impurity

SZ CAT No:	: SZ-T012083
CAS No	: NA
Mol.F.	: C22H29N6O5P
Mol.Wt.	: 488.5
Inv. Status	: Custom Synthesis

Tenofovir Imine Impurity

SZ CAT No:	: SZ-T012084
CAS No	: NA
Mol.F.	: C10H14N5O4P
Mol.Wt.	: 299.2
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide N-Hydroxy Methyl Impurity

SZ CAT No:	: SZ-T012085
CAS No	: NA
Mol.F.	: C22H31N6O6P
Mol.Wt.	: 506.5
Inv. Status	: Custom Synthesis

Tenofovir Dimer

SZ CAT No:	: SZ-T012086
CAS No	: 1962114-87-9
Mol.F.	: C19H28N10O8P2
Mol.Wt.	: 586.4
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide Dimer Impurity 2

SZ CAT No:	: SZ-T012087
CAS No	: NA
Mol.F.	: C31H50N12O10P2
Mol.Wt.	: 812.8
Inv. Status	: Custom Synthesis

Tenofovir Alfenamide N-hydroxy methyl methoxy impurity

SZ CAT No:	: SZ-T012088
CAS No	: NA
Mol.F.	: C24H35N6O8P
Mol.Wt.	: 566.6
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide Dimer Impurity 1

SZ CAT No:	: SZ-T012089
CAS No	: NA
Mol.F.	: C43H58N12O10P2
Mol.Wt.	: 965.0
Inv. Status	: In Stock

Des-Phenol Tenofovir Alafenamide Imine Impurity

SZ CAT No:	: SZ-T012090
CAS No	: NA
Mol.F.	: C16H25N6O5P
Mol.Wt.	: 412.4
Inv. Status	: Custom Synthesis

Des-Phenol Tenofovir Alfenamide+Tenofovir Alafenamide Dimer

SZ CAT No:	: SZ-T012091
CAS No	: NA
Mol.F.	: C37H54N12O10P2
Mol.Wt.	: 888.9
Inv. Status	: Custom Synthesis

Tenofovir Alafenamide Glycosamine product

SZ CAT No:	: SZ-T012092
CAS No	: NA
Mol.F.	: C33H49N6O15P
Mol.Wt.	: 800.8
Inv. Status	: Custom Synthesis

Tenofovie Alfenamide Amadori Rearrangement product

SZ CAT No:	: SZ-T012093
CAS No	: NA
Mol.F.	: C33H49N6O15P
Mol.Wt.	: 800.8
Inv. Status	: Custom Synthesis

Tenofovir Impurity 49

SZ CAT No:	: SZ-T012094
CAS No	: NA
Mol.F.	: C18H26N10O7P2
Mol.Wt.	: 556.4
Inv. Status	: Custom Synthesis

Tenofovir Impurity 50

SZ CAT No:	: SZ-T012095
CAS No	: NA
Mol.F.	: C19H28N10O8P2
Mol.Wt.	: 586.4
Inv. Status	: Custom Synthesis

Tenofovir Impurity 51

SZ CAT No:	: SZ-T012096
CAS No	: NA
Mol.F.	: C18H28N5O9P
Mol.Wt.	: 489.4
Inv. Status	: Custom Synthesis

Tenofovir Impurity 52

SZ CAT No:	: SZ-T012097
CAS No	: NA
Mol.F.	: C23H38N5O14P
Mol.Wt.	: 639.6
Inv. Status	: Custom Synthesis

Tenofovir Disoproxil Related Compound G

SZ CAT No:	: SZ-T012098
CAS No	: 1884329-63-8
Mol.F.	: C8H10BrN5
Mol.Wt.	: 256.1
Inv. Status	: In Stock

Tenofovir Impurity 53

SZ CAT No:	: SZ-T012099
CAS No	: 50615-40-2
Mol.F.	: C8H10ClN5
Mol.Wt.	: 211.7
Inv. Status	: In Stock