Tadalafil Impurity 12

SZ CAT No:	SZ-T007026
CAS No	326-61-4
Mol.F.	C10H10O4
Mol.Wt.	194.2
Inv. Status	Custom Synthesis

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Chemical Name: Benzo[d][1,3]dioxol-5-ylmethyl acetate

Synonym: Piperonyl acetate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(OCC1=CC(OCO2)=C2C=C1)=O

Quantification of Genotoxic Impurities in Tadalafil by Simple and Sensitive Gas Chromatography Technique
Ajit Anerao,Bhushan Patil,Vishal Solse &Chandrakant Patil
Analytical Chemistry Letters Volume 9, 2019 - Issue 4 Pages 518-525

Chiral Separation of Two Pairs of Enantiomers of Tadalafil by High-Performance Liquid Chromatography
Wenhui Gao, Zhefeng Zhang, Zhiwei Li, and Guijian Liang
Journal of Chromatographic Science, Vol. 45, September 2007

Fast ultra‐high‐performance liquid chromatography with diode array and mass spectrometry method for determination of tadalafil drug substance and its impurities
Ludovit Schreiber Radoslav Halko Milan Hutta
Biomedical Chromatography Volume31, Issue12 December 2017 e4020

Validation and stability indicating RP-HPLC method for the determination of tadalafil API in pharmaceutical formulations
B. Prasanna Reddy , K. Amarnadh Reddy and M. S. Reddy
Research In Pharmaceutical Biotechnology Vol. 2(1), pp. 001-006

Stability-indicating methods for determination of tadalafil in presence of its degradation product
Moataz A.Yehia*, Mamdouh R.Rezk, Mohamed A.El-Sayed, Mohamed Abdel Kawy
ACAIJ, 14(9) 2014 [351-362]

Tadalafil Impurity 12 is chemically Benzo[d][1,3]dioxol-5-ylmethyl acetate. It is also known as Piperonyl acetate. Tadalafil Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Tadalafil Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tadalafil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Tadalafil Impurity 12

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SZ CAT No:	: SZ-T007001
CAS No	: 171596-29-5
Mol.F.	: C22H19N3O4
Mol.Wt.	: 389.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007002
CAS No	: 171596-27-3
Mol.F.	: C22H19N3O4
Mol.Wt.	: 389.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007003
CAS No	: 629652-72-8
Mol.F.	: C22H19N3O4
Mol.Wt.	: 389.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007004
CAS No	: NA
Mol.F.	: C22H19N3O4 : HCl : 3(H2O)
Mol.Wt.	: 389.4 : 36.5 : 3(18.0)
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007005
CAS No	: NA
Mol.F.	: C22H19N3O6
Mol.Wt.	: 421.4
Inv. Status	: Under Synthesis

SZ CAT No:	: SZ-T007006
CAS No	: 1978322-99-4
Mol.F.	: C22H19N3O6
Mol.Wt.	: 421.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007007
CAS No	: 2747958-44-5
Mol.F.	: C22H19N3O6
Mol.Wt.	: 421.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007008
CAS No	: 2520114-46-7
Mol.F.	: C22H17N3O5
Mol.Wt.	: 403.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007009
CAS No	: 1978322-98-3
Mol.F.	: C22H19N3O6
Mol.Wt.	: 421.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007010
CAS No	: 2378614-29-8
Mol.F.	: C22H19N3O5
Mol.Wt.	: 405.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007011
CAS No	: 1093940-69-2
Mol.F.	: C21H18N4O4
Mol.Wt.	: 390.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007012
CAS No	: 14907-27-8
Mol.F.	: C12H14N2O2 : HCl
Mol.Wt.	: 218.3 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007013
CAS No	: 171752-68-4
Mol.F.	: C20H18N2O4 : HCl
Mol.Wt.	: 350.4 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007014
CAS No	: 171489-59-1
Mol.F.	: C22H19ClN2O5
Mol.Wt.	: 426.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007015
CAS No	: NA
Mol.F.	: C22H19N3O4
Mol.Wt.	: 389.4
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-T007016
CAS No	: 171596-43-3
Mol.F.	: C20H18N2O4
Mol.Wt.	: 350.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007D01
CAS No	: 960226-55-5
Mol.F.	: C22H16D3N3O4
Mol.Wt.	: 392.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007017
CAS No	: 2520114-84-3
Mol.F.	: C21H19N3O4
Mol.Wt.	: 377.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007018
CAS No	: NA
Mol.F.	: C21H19N3O4
Mol.Wt.	: 377.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007019
CAS No	: 1797099-86-5
Mol.F.	: C21H19N3O4
Mol.Wt.	: 377.4
Inv. Status	: Custom Synthesis

Tadalafil Impurity 12

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SZ CAT No:	: SZ-T007020
CAS No	: 20850-43-5
Mol.F.	: C8H7ClO2
Mol.Wt.	: 170.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007021
CAS No	: 749864-17-3
Mol.F.	: C20H18N2O4
Mol.Wt.	: 350.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007022
CAS No	: 2520114-95-6
Mol.F.	: C24H20ClN3O5
Mol.Wt.	: 465.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007023
CAS No	: 7797-83-3
Mol.F.	: C8H6O3
Mol.Wt.	: 150.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-T007024
CAS No	: 495-76-1
Mol.F.	: C8H8O3
Mol.Wt.	: 152.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007025
CAS No	: 769-30-2
Mol.F.	: C8H8O3
Mol.Wt.	: 152.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007026
CAS No	: 326-61-4
Mol.F.	: C10H10O4
Mol.Wt.	: 194.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007027
CAS No	: NA
Mol.F.	: C22H18N4O5
Mol.Wt.	: 418.4
Inv. Status	: Inquire

SZ CAT No:	: SZ-T007028
CAS No	: NA
Mol.F.	: C24H20Cl2N2O6
Mol.Wt.	: 503.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T007029
CAS No	: NA
Mol.F.	: C22H21N3O5
Mol.Wt.	: 407.4
Inv. Status	: Custom Synthesis