Salbutamol EP Impurity N

SZ CAT No:	SZ-S003015
CAS No	149222-15-1
Mol.F.	C26H40N2O5
Mol.Wt.	460.6
Inv. Status	In Stock

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Chemical Name: 4-[(1Ξ)-2-(tert-butylamino)-1-hydroxyethyl]-2-[[5-[(1Ξ)-2-(tert-butylamino)-1-hydroxyethyl]-2-hydroxyphenyl]methyl]-6-(hydroxymethyl)phenol (as per EP)

Synonym: Salbutamol BP Impurity N ; Albuterol Dimer

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OCC1=C(O)C(CC2=CC(C(O)CNC(C)(C)C)=CC=C2O)=CC(C(O)CNC(C)(C)C)=C1

Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
AmandineDispasaVincentDesfontainebBertylAndriaPierreLebrunacDorinaKotonidAdrianClarkedDavyGuillarmebPhilippeHuberta
Journal of Pharmaceutical and Biomedical Analysis
Volume 134, 5 February 2017, Pages 170-180

Evolved gas analysis during thermal degradation of salbutamol sulphate
Fabio Sonvico, Victoria Coleman, Daniela Traini & Paul M. Young
Journal of Thermal Analysis and Calorimetry volume 120, pages789–794 (2015)

A chromatography-free synthesis of racemic salbutamol hemisulfate
AgatheVanoostLaurentPetit
Tetrahedron Letters
Volume 61, Issue 28, 9 July 2020, 152126

Salbutamol EP Impurity N is chemically 4-[(1Ξ)-2-(tert-butylamino)-1-hydroxyethyl]-2-[[5-[(1Ξ)-2-(tert-butylamino)-1-hydroxyethyl]-2-hydroxyphenyl]methyl]-6-(hydroxymethyl)phenol (as per EP). It is also known as Salbutamol BP Impurity N ; Albuterol Dimer. Salbutamol EP Impurity N is supplied with detailed characterization data compliant with regulatory guideline. Salbutamol EP Impurity N can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Salbutamol .

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Salbutamol

SZ CAT No:	: SZ-S003001
CAS No	: 18559-94-9
Mol.F.	: C13H21NO3
Mol.Wt.	: 239.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 51293-66-4 (HCl salt) ; 39971-61-4 (Sulfate salt)

Salbutamol EP Impurity A

SZ CAT No:	: SZ-S003002
CAS No	: 870076-72-5
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: In Stock
Rel. CAS No	: 2468639-65-6 (HCl salt)

Salbutamol EP Impurity B

SZ CAT No:	: SZ-S003003
CAS No	: 96948-64-0
Mol.F.	: C12H19NO2
Mol.Wt.	: 209.3
Inv. Status	: In Stock
Rel. CAS No	: 112337-52-7 (HCl salt)

Salbutamol EP Impurity C

SZ CAT No:	: SZ-S003004
CAS No	: 18910-68-4
Mol.F.	: C13H21NO2
Mol.Wt.	: 223.3
Inv. Status	: In Stock
Rel. CAS No	: 70334-18-8 (HCl salt) ; 1956308-05-6 (Sulfate salt) ; 2044704-57-4 (hemisulfate salt)

Salbutamol EP Impurity D

SZ CAT No:	: SZ-S003005
CAS No	: 156339-88-7
Mol.F.	: C13H19NO3
Mol.Wt.	: 237.3
Inv. Status	: In Stock
Rel. CAS No	: 2624100-96-3 (Sulfate salt)

Salbutamol EP Impurity E

SZ CAT No:	: SZ-S003006
CAS No	: 24085-03-8
Mol.F.	: C20H27NO3
Mol.Wt.	: 329.4
Inv. Status	: In Stock
Rel. CAT No	: SZ-L065008 ,

Salbutamol EP Impurity F

SZ CAT No:	: SZ-S003007
CAS No	: 147663-30-7
Mol.F.	: C26H40N2O5
Mol.Wt.	: 460.6
Inv. Status	: In Stock

Salbutamol EP Impurity G

SZ CAT No:	: SZ-S003008
CAS No	: 64092-10-0
Mol.F.	: C20H25NO3
Mol.Wt.	: 327.4
Inv. Status	: In Stock
Rel. CAS No	: 24085-08-3 (HCl salt)
Rel. CAT No	: SZ-L065010 ; SZ-S003043 ,

Salbutamol EP Impurity H

SZ CAT No:	: SZ-S003009
CAS No	: 132183-64-3
Mol.F.	: C13H21NO
Mol.Wt.	: 207.3
Inv. Status	: In Stock
Rel. CAS No	: 2252153-95-8 (HCl salt)
Rel. CAT No	: SZ-L065011 ,

Salbutamol EP Impurity I

SZ CAT No:	: SZ-S003010
CAS No	: 56796-66-8
Mol.F.	: C20H27NO3
Mol.Wt.	: 329.4
Inv. Status	: In Stock
Rel. CAT No	: SZ-L065012 ,

Salbutamol EP Impurity J

SZ CAT No:	: SZ-S003011
CAS No	: 156547-62-5
Mol.F.	: C13H19NO3
Mol.Wt.	: 237.3
Inv. Status	: Limited Stock
Rel. CAS No	: 41489-89-8 (HCl salt)

Salbutamol EP Impurity K

SZ CAT No:	: SZ-S003012
CAS No	: 898542-80-8
Mol.F.	: C13H18ClNO3
Mol.Wt.	: 271.7
Inv. Status	: Out of Stock

Salbutamol EP Impurity L Hydrochloride

SZ CAT No:	: SZ-S003013
CAS No	: NA
Mol.F.	: C13H20ClNO3 : HCl
Mol.Wt.	: 273.8 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 898542-81-9 (free base)

Salbutamol EP Impurity M

SZ CAT No:	: SZ-S003014
CAS No	: 18910-70-8
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: In Stock
Rel. CAS No	: 27566-30-9 (HCl salt)

Salbutamol EP Impurity N

SZ CAT No:	: SZ-S003015
CAS No	: 149222-15-1
Mol.F.	: C26H40N2O5
Mol.Wt.	: 460.6
Inv. Status	: In Stock

Albuterol USP Related Compound F

SZ CAT No:	: SZ-S003016
CAS No	: 1221742-55-7
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: Out of Stock, Custom Synthesis

Salbutamol Diethyl Ether

SZ CAT No:	: SZ-S003017
CAS No	: 1221726-71-1
Mol.F.	: C17H29NO3
Mol.Wt.	: 295.4
Inv. Status	: In Stock

Salbutamol Sulfate

SZ CAT No:	: SZ-S003018
CAS No	: 51022-70-9
Mol.F.	: C13H21NO3 : 1/2(H2SO4)
Mol.Wt.	: 239.3 : 1/2(98.1)
Inv. Status	: In Stock
Rel. CAS No	: 51293-66-4 (HCl salt) ; 18559-94-9 (free base)

Salbutamol Glyoxal Impurity

SZ CAT No:	: SZ-S003020
CAS No	: 72189-44-7
Mol.F.	: C9H10O5
Mol.Wt.	: 198.2
Inv. Status	: Custom Synthesis

(±)-4-O-Ethyl Albuterol

SZ CAT No:	: SZ-S003021
CAS No	: 2387728-91-6
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: In Stock
Rel. CAS No	: 2724765-08-4 (Sulfate salt)

Salbutamol EP Impurity P

SZ CAT No:	: SZ-S003022
CAS No	: NA
Mol.F.	: C22H31NO6
Mol.Wt.	: 405.5
Inv. Status	: Custom Synthesis

Salbutamol Related Compound 1

SZ CAT No:	: SZ-S003023
CAS No	: 156339-89-8
Mol.F.	: C20H27NO4
Mol.Wt.	: 345.4
Inv. Status	: Custom Synthesis

Salbutamol Related Compound 2

SZ CAT No:	: SZ-S003024
CAS No	: 51234-21-0
Mol.F.	: C9H8O4
Mol.Wt.	: 180.2
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity Q

SZ CAT No:	: SZ-S003025
CAS No	: 54030-32-9
Mol.F.	: C8H8O3
Mol.Wt.	: 152.1
Inv. Status	: In Stock

(R)-Salbutamol Hydrochloride

SZ CAT No:	: SZ-S003026
CAS No	: 50293-90-8
Mol.F.	: C13H21NO3 : HCl
Mol.Wt.	: 239.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 34391-04-3 (Free base)

(S)-Salbutamol

SZ CAT No:	: SZ-S003027
CAS No	: 34271-50-6
Mol.F.	: C13H21NO3
Mol.Wt.	: 239.3
Inv. Status	: In Stock
Rel. CAS No	: 50293-91-9 (HCl salt)

5-Hydroxy Salbutamol

SZ CAT No:	: SZ-S003028
CAS No	: 182676-90-0
Mol.F.	: C13H21NO4
Mol.Wt.	: 255.3
Inv. Status	: In Stock

Salbutamol 4-O-sulfate

SZ CAT No:	: SZ-S003029
CAS No	: 63908-03-2
Mol.F.	: C13H21NO6S
Mol.Wt.	: 319.4
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity O (HCl salt)

SZ CAT No:	: SZ-S003030
CAS No	: 69716-64-9
Mol.F.	: C15H25NO3 : HCl
Mol.Wt.	: 267.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 754926-25-5 (free base)
Rel. CAT No	: SZ-S003065 ,

Salbutamol Impurity 1

SZ CAT No:	: SZ-S003031
CAS No	: NA
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: Custom Synthesis

Salbutamol Impurity 2

SZ CAT No:	: SZ-S003032
CAS No	: NA
Mol.F.	: C19H25NO5
Mol.Wt.	: 347.4
Inv. Status	: Custom Synthesis

Salbutamol Impurity 3

SZ CAT No:	: SZ-S003033
CAS No	: NA
Mol.F.	: C32H44N2O8
Mol.Wt.	: 584.7
Inv. Status	: Custom Synthesis

Salbutamol D3

SZ CAT No:	: SZ-S003D01
CAS No	: 1219798-60-3
Mol.F.	: C13H18D3NO3
Mol.Wt.	: 242.3
Inv. Status	: Out of Stock

Rac Albuterol D9

SZ CAT No:	: SZ-S003D02
CAS No	: 1173021-73-2
Mol.F.	: C13H12D9NO3
Mol.Wt.	: 248.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1781417-68-2 (acetate salt)

Salbutamol 4-o-Sulfate D9

SZ CAT No:	: SZ-S003D03
CAS No	: NA
Mol.F.	: C13H12D9NO6S
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 63908-03-2 (Unlabeled)

Colterol

SZ CAT No:	: SZ-S003035
CAS No	: 18866-78-9
Mol.F.	: C12H19NO3
Mol.Wt.	: 225.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 52872-37-4 (HCl salt) ; 99798-66-0 (Sulfate salt)

Salbutamol Impurity 21

SZ CAT No:	: SZ-S003019
CAS No	: NA
Mol.F.	: C20H24N2O5
Mol.Wt.	: 372.4
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity K (hemihydrate)

SZ CAT No:	: SZ-S003037
CAS No	: NA
Mol.F.	: C13H18ClNO3 : 1/2(H2O)
Mol.Wt.	: 271.7 : 1/2(18.0)
Inv. Status	: In Stock
Rel. CAS No	: 898542-80-8 (free base)

Salbutamol Hydrochloride

SZ CAT No:	: SZ-S003036
CAS No	: 51293-66-4
Mol.F.	: C13H21NO3 : HCl
Mol.Wt.	: 239.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 18559-94-9 (free base) ; 39971-61-4 (Sulfate salt)

Salbutamol EP Impurity G Hydrochloride

SZ CAT No:	: SZ-S003043
CAS No	: 24085-08-3
Mol.F.	: C20H25NO3 : HCl
Mol.Wt.	: 327.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 64092-10-0 (free base)
Rel. CAT No	: SZ-S003008 ,

Orellanine

SZ CAT No:	: SZ-M039890
CAS No	: 37338-80-0
Mol.F.	: C10H8N2O6
Mol.Wt.	: 252.2
Inv. Status	: Custom Synthesis

Salbutamol Nitroso Impurity 1

SZ CAT No:	: SZ-S003048
CAS No	: 2919946-71-5
Mol.F.	: C13H20N2O4
Mol.Wt.	: 268.3
Inv. Status	: In Stock

Salbutamol Impurity 4

SZ CAT No:	: SZ-S003040
CAS No	: 934842-69-0
Mol.F.	: C32H43NO4
Mol.Wt.	: 505.7
Inv. Status	: Custom Synthesis

Salbutamol Impurity 5

SZ CAT No:	: SZ-S003049
CAS No	: NA
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity O

SZ CAT No:	: SZ-S003065
CAS No	: 754926-25-5
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: In Stock
Rel. CAS No	: 69716-64-9 (HCl salt)
Rel. CAT No	: SZ-S003030 ,

Salbutamol EP Impurity N Isomer 1 (SS+RR)

SZ CAT No:	: SZ-S003067
CAS No	: NA
Mol.F.	: C26H40N2O5
Mol.Wt.	: 460.6
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity N Isomer 2(SR+RS)

SZ CAT No:	: SZ-S003068
CAS No	: NA
Mol.F.	: C26H40N2O5
Mol.Wt.	: 460.6
Inv. Status	: Custom Synthesis

Salbutamol Impurity 7

SZ CAT No:	: SZ-S003069
CAS No	: NA
Mol.F.	: C22H25NO3
Mol.Wt.	: 351.4
Inv. Status	: Custom Synthesis

Salbutamol Impurity 8

SZ CAT No:	: SZ-S003070
CAS No	: 62508-15-0
Mol.F.	: C19H23NO2
Mol.Wt.	: 297.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 78022-25-0 (HCl salt)

Salbutamol Impurity 9

SZ CAT No:	: SZ-S003071
CAS No	: NA
Mol.F.	: C22H27NO4
Mol.Wt.	: 369.5
Inv. Status	: Custom Synthesis

Salbutamol Impurity 10

SZ CAT No:	: SZ-S003072
CAS No	: NA
Mol.F.	: C22H27NO4
Mol.Wt.	: 369.5
Inv. Status	: Custom Synthesis

Salbutamol Impurity 11

SZ CAT No:	: SZ-S003073
CAS No	: NA
Mol.F.	: C31H40N2O2
Mol.Wt.	: 472.7
Inv. Status	: Custom Synthesis

Salbutamol EP Impurity N

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