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Posaconazole Enantiomer

SZ CAT No SZ-P022015
CAS No 2243785-97-7 
Mol.F. C37H42F2N8O4
Mol.Wt. 700.8
Inv. Status Limited Stock

Chemical Name: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Synonym: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Separation of twelve posaconazole related stereoisomers by multiple heart-cutting chiral–chiral two-dimensional liquid chromatography

Feng Xua , Yao Xua,b , Guizheng Liua,c , Meng Zhanga,c , Shangshang Qianga,b , Jingwu Kang.

Journal of Chromatography A Volume 1618, 10 May 2020, 460845

Molecular Dynamics of Supercooled Pharmaceutical Agent Posaconazole Studied via Differential Scanning Calorimetry, Dielectric and Mechanical Spectroscopies

K. Adrjanowicz, K. Kaminski, P. Wlodarczyk, K. Grzybowska, M. Tarnacka, D. Zakowiecki, G. Garbacz, M Paluch, and S. Jurga

Mol. Pharmaceutics 2013, 10, 10, 3934–3945

Development and Validation of Chiral HPLC Methodfor the Identification and Quantification of Enantiomer in Posaconazole Drug Substance


Chemical Science Transactions 7(3), 506-514

Simultaneous Quantification of Benznidazole and Posaconazole by HPLC-DAD Using QbD Approach

Ana Cristina Sousa Gramoza Vilarinho Santana, Lucas José de Alencar Danda, Livio Cesar Cunha Nunes, Jose Lamartine Soares Sobrinho

Journal of Chromatographic Science, Volume 57, Issue 2, February 2019, Pages 156–162


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