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Posaconazole Enantiomer

SZ CAT No SZ-P022015
CAS No 2243785-97-7 
Mol.F. C37H42F2N8O4
Mol.Wt. 700.8
Inv. Status Limited Stock


Chemical Name: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Synonym: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Separation of twelve posaconazole related stereoisomers by multiple heart-cutting chiral–chiral two-dimensional liquid chromatography
Feng Xua , Yao Xua,b , Guizheng Liua,c , Meng Zhanga,c , Shangshang Qianga,b , Jingwu Kang.
Journal of Chromatography A Volume 1618, 10 May 2020, 460845
 
Molecular Dynamics of Supercooled Pharmaceutical Agent Posaconazole Studied via Differential Scanning Calorimetry, Dielectric and Mechanical Spectroscopies
K. Adrjanowicz, K. Kaminski, P. Wlodarczyk, K. Grzybowska, M. Tarnacka, D. Zakowiecki, G. Garbacz, M Paluch, and S. Jurga
Mol. Pharmaceutics 2013, 10, 10, 3934–3945
 
Development and Validation of Chiral HPLC Methodfor the Identification and Quantification of Enantiomer in Posaconazole Drug Substance
Cherukuru nagaraju1,2,*, uttam kumar ray1 and siddaiah vidavalur
Chemical Science Transactions 7(3), 506-514
 
Simultaneous Quantification of Benznidazole and Posaconazole by HPLC-DAD Using QbD Approach
Ana Cristina Sousa Gramoza Vilarinho Santana, Lucas José de Alencar Danda, Livio Cesar Cunha Nunes, Jose Lamartine Soares Sobrinho
Journal of Chromatographic Science, Volume 57, Issue 2, February 2019, Pages 156–162

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