Paroxetine Isoproyl Tosylate

SZ CAT No:	SZ-P012050
CAS No	217797-18-7
Mol.F.	C19H20FNO3 : C10H14O3S
Mol.Wt.	329.4 : 214.3
Inv. Status	Custom Synthesis
Rel. CAS No	61869-08-7 (free base) ; 78246-49-8 (HCl salt)

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Chemical Name: Isopropyl 4-methylbenzenesulfonate compound with (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (1:1)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=S(OC(C)C)(C1=CC=C(C)C=C1)=O.FC2=CC=C(C=C2)[C@H]3[C@@H](CNCC3)COC4=CC(OCO5)=C5C=C4

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolff
Journal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig
Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography
abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy
Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

Spectral Characterization of Degradation Impurities of Paroxetine Hydrochloride Hemihydrate
nirmala munigela, j. moses babu , anjaneyulu yerramilli , naveen kumar kolla , vyas krishnamurthy, vijay vittal mathad
Sci Pharm. 2008; 76; 653–661.

Paroxetine Isoproyl Tosylate is chemically Isopropyl 4-methylbenzenesulfonate compound with (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (1:1). Paroxetine Isoproyl Tosylate is supplied with detailed characterization data compliant with regulatory guideline. Paroxetine Isoproyl Tosylate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paroxetine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Paroxetine Isoproyl Tosylate

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