Metoprolol Hydroxy Epoxide Impurity

SZ CAT No:	SZ-M021020
CAS No	104857-48-9
Mol.F.	C11H14O3
Mol.Wt.	194.2
Inv. Status	In Stock

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Chemical Name: 1-[2-(2-Hydroxyethyl)phenyoxy]-2,3-epoxypropane

Synonym: Metoprolol Hydroxy Epoxide Impurity

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OCCC1=CC=C(OCC2CO2)C=C1

Identification of a new by-product detected in metoprolol tartrate
magnus erickson,$ karl-erik karlsson,$ bo lamm,§ sam larsson,$ lars a. svensson$ and jorgen vessman
Journal of Pharmaceutical & Biomedical Analysis, Vol. 13, No. 4/5, pp. 567-574, 1995

An improved validated HPLC method for separation of metoprolol and hydrochlorothiazide impurities in metoprolol and hydrochlorothiazide tablets
Avinash S. Patil, Shakil S. Sait, Abhijit Deshamukh and Girish Deshpande
Der Pharmacia Lettre, 2015, 7 (2):183-190

Simultaneous Quantitative Determination of Metoprolol, Atorvastatin and Ramipril in Capsules by a Validated Stability-Indicating RP-UPLC Method
raja kumar seshadri * 1 , makarand madhukar desai 1 , thummala veera raghavaraju 1 , deepa krishnan 1 , dama venugopala rao 1 , ivon elisha chakravarthy
Sci Pharm. 2010; 78: 821–834

Development and validation of a stability indicating RP-HPLC method for determination of metoprolol succinate in pharmaceutical dosage forms
1CH. Naveen Kumar*, 1 Saraswathi Mannuri, 1Vijaya Kuchana and 2N. Kannappan
Der Pharmacia Sinica, 2014, 5(6):69-78

Metoprolol Hydroxy Epoxide Impurity is chemically 1-[2-(2-Hydroxyethyl)phenyoxy]-2,3-epoxypropane. It is also known as Metoprolol Hydroxy Epoxide Impurity. Metoprolol Hydroxy Epoxide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Metoprolol Hydroxy Epoxide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Metoprolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-M021031
CAS No	: NA
Mol.F.	: C14H20NO4 : Na
Mol.Wt.	: 266.3 : 23.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 56392-14-4 (free base) ; 207287-28-3 (HCl salt)

SZ CAT No:	: SZ-M021007
CAS No	: 1956321-87-1
Mol.F.	: C13H19NO3 : HCl
Mol.Wt.	: 237.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 29122-74-5 (free base) ; 1639933-77-9 (oxalate salt)
Rel. CAT No	: SZ-B003011 ,

SZ CAT No:	: SZ-M021012
CAS No	: NA
Mol.F.	: C14H23NO3 : HCl
Mol.Wt.	: 253.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 62572-94-5 (free base)

SZ CAT No:	: SZ-M021015
CAS No	: 73313-36-7
Mol.F.	: C9H22N2O : 2HCl
Mol.Wt.	: 174.3 : 2(36.5)
Inv. Status	: In Stock
Rel. CAS No	: 343785-33-1 (free base)

SZ CAT No:	: SZ-M021016
CAS No	: NA
Mol.F.	: C6H15NO2 : HCl
Mol.Wt.	: 133.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 6452-57-9 (free base) ; 73313-34-5 (oxalate salt)

Metoprolol Hydroxy Epoxide Impurity

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SZ CAT No:	: SZ-M021029
CAS No	: 29112-40-1
Mol.F.	: C16H25NO4
Mol.Wt.	: 295.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021030
CAS No	: 29121-23-1
Mol.F.	: C15H23NO4
Mol.Wt.	: 281.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021032
CAS No	: 230975-30-1
Mol.F.	: C21H28O5
Mol.Wt.	: 360.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021005
CAS No	: 109632-08-8
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: In Stock

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Mol.F.	: C9H12O2
Mol.Wt.	: 152.2
Inv. Status	: In Stock

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CAS No	: 62572-90-1
Mol.F.	: C12H18O4
Mol.Wt.	: 226.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021009
CAS No	: 163685-38-9
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: In Stock

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CAS No	: 7695-63-8
Mol.F.	: C12H19NO2
Mol.Wt.	: 209.3
Inv. Status	: In Stock

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CAS No	: 501-94-0
Mol.F.	: C8H10O2
Mol.Wt.	: 138.2
Inv. Status	: In Stock

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CAS No	: 163685-37-8
Mol.F.	: C18H31NO5
Mol.Wt.	: 341.4
Inv. Status	: In Stock

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CAS No	: 1486464-40-7
Mol.F.	: C27H41NO6 : HCl
Mol.Wt.	: 475.6 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 154784-36-8 (free base)
Rel. CAT No	: SZ-M021056 ,

SZ CAT No:	: SZ-M021018
CAS No	: 76805-25-9
Mol.F.	: C13H16O4
Mol.Wt.	: 236.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021019
CAS No	: 122-60-1
Mol.F.	: C9H10O2
Mol.Wt.	: 150.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021020
CAS No	: 104857-48-9
Mol.F.	: C11H14O3
Mol.Wt.	: 194.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021021
CAS No	: 17138-28-2
Mol.F.	: C10H12O3
Mol.Wt.	: 180.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021022
CAS No	: 56718-70-8
Mol.F.	: C12H16O3
Mol.Wt.	: 208.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021023
CAS No	: 81024-43-3
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021024
CAS No	: 81024-42-2
Mol.F.	: C15H25NO3
Mol.Wt.	: 267.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021025
CAS No	: 98418-47-4
Mol.F.	: C15H25NO3 : 1/2(C4H6O4)
Mol.Wt.	: 267.4 : 1/2(118.1)
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021026
CAS No	: 56392-17-7
Mol.F.	: C15H25NO3 : 1/2(C4H6O6)
Mol.Wt.	: 267.37 : 1/2(150.1)
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021027
CAS No	: 56718-76-4
Mol.F.	: C12H17ClO3
Mol.Wt.	: 244.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021028
CAS No	: 538-43-2
Mol.F.	: C9H12O3
Mol.Wt.	: 168.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021033
CAS No	: NA
Mol.F.	: C28H47NO11
Mol.Wt.	: 573.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021D01
CAS No	: 959786-79-9
Mol.F.	: C15H20D5NO3
Mol.Wt.	: 272.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021D02
CAS No	: 959787-96-3
Mol.F.	: C15H18D7NO3
Mol.Wt.	: 274.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M021D03
CAS No	: NA
Mol.F.	: C27H31D10NO6
Mol.Wt.	: 485.7
Inv. Status	: Custom Synthesis
Rel. CAS No	: 154784-36-8 (Unlabeled)

SZ CAT No:	: SZ-M021034
CAS No	: 84803-56-5
Mol.F.	: C9H13NO
Mol.Wt.	: 151.2
Inv. Status	: In Stock
Rel. CAS No	: 1803612-33-0 (HCl salt)

SZ CAT No:	: SZ-M021035
CAS No	: 73723-85-0
Mol.F.	: C15H23NO4
Mol.Wt.	: 281.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 68416-39-7 (HCl salt)

SZ CAT No:	: SZ-M021036
CAS No	: 138768-62-4
Mol.F.	: C15H24N2O4
Mol.Wt.	: 296.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-M021037
CAS No	: NA
Mol.F.	: C19H29NO6
Mol.Wt.	: 367.4
Inv. Status	: Custom Synthesis