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Ezetimibe Impurity 46

SZ CAT No SZ-E026105
CAS No 2743547-96-6
Mol.F. C24H22FNO3
Mol.Wt. 391.4
Inv. Status Custom Synthesis


Chemical Name: (3R,4S)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one

Smiles: O[C@@H](CC[C@H]1C(N(C2=CC=CC=C2)[C@@H]1C3=CC=C(O)C=C3)=O)C4=C(F)C=CC=C4

Inchi: InChI=1S/C21H23NO4/c23-20(16-7-3-1-4-8-16)18-10-9-17(15-19(18)21(24)25)26-14-13-22-11-5-2-6-12-22/h1,3-4,7-10,15H,2,5-6,11-14H2,(H,24,25)

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281