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Ethinylestradiol Impurity 4

SZ CAT No SZ-E007021
CAS No 303014-89-3
Mol.F. C40H46O4
Mol.Wt. 590.8
Inv. Status Custom Synthesis


Chemical Name: [2,​4'-​Bi-​19-​norpregna-​1,​3,​5(10)​-​trien-​20-​yne]​-​3,​3',​17,​17'-​tetrol, (17α)​-​(17'α)​- (9CI)

Smiles: C[C@@]12[C@](CC[C@]2(C#C)O)([H])[C@]3([H])CCC4=C(C5=CC([C@](CC[C@@]6(C)[C@@]7([H])CC[C@@]6(O)C#C)([H])[C@@]7([H])CC8)=C8C=C5O)C(O)=CC=C4[C@@]3([H])CC1

Inchi: InChI=1S/C40H46O4/c1-5-39(43)17-13-33-27-9-7-23-19-35(41)31(21-29(23)25(27)11-15-37(33,39)3)32-22-30-24(20-36(32)42)8-10-28-26(30)12-16-38(4)34(28)14-18-40(38,44)6-2/h1-2,19-22,25-28,33-34,41-44H,7-18H2,3-4H3/t25-,26-,27+,28+,33-,34-,37-,38-,39-,40-/m0/s1

Reversed-​phase high-​performance liquid chromatographic determination of Norethindrone acetate and ethinyl estradiol in pharmaceutical formulation
By Koneru, Ajitha; Kimbahune, Ritu; Mubeen, G.; Lalitha, N.; Chakraborty, Krishnasis
From Indo American Journal of Pharmaceutical Research (2015), 5(6), 2442-2449
 
Analytical method development and validation for simultaneous determination and quantification of Ethinyl Estradiol and Gestodene in combined tablet dosage form by RP-​HPLC
By Nautiyal, Kanchan; Ramakrishna, K.
From Journal of Chemical and Pharmaceutical Research (2014), 6(10), 74-80
 
Simultaneous determination of ethinyl estradiol and drospirenone in oral contraceptive by high performance liquid chromatography
By Silva, Viviane Benevenuti; Galdos, Angel Arturo Gaona; Mothe, Cintia Maria Alves; Pallastrelli, Michele Bacchi; Prado, Maria Segunda Aurora; Singh, Anil Kumar; Kedor-Hackmann, Erika Rosa Maria; Santoro, Maria Ines Rocha Miritello
From Brazilian Journal of Pharmaceutical Sciences (2013), 49(3), 521-528
 
New oxidative decomposition mechanism of estradiol through the structural characterization of a minute impurity and its degradants
By Beni, Zoltan; Hada, Viktor; Varga, Emese; Maho, Sandor; Aranyi, Antal; Szantay, Csaba, Jr.
From Journal of Pharmaceutical and Biomedical Analysis (2013), 78-79, 183-189