Dapagliflozin USP Related Compound A

SZ CAT No:	SZ-D015001
CAS No	1807632-95-6
Mol.F.	C21H25BrO6
Mol.Wt.	453.3
Inv. Status	In Stock

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Chemical Name: (2S,3R,4R,5S,6R)-2-[4-Bromo-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (as per USP)

Synonym: Dapagliflozin 4-Bromo Analog ; Dapagliflozin Impurity-S3C (Bromo Dapagliflozin)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@H]1[C@H](C2=CC(CC3=CC=C(OCC)C=C3)=C(Br)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Stability indicating rp-hplc method for simultaneous estimation of dapagliflozin and saxagliptin in pharmaceutical dosage forms
By Thota, Hanisha; Soundarya, G.
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9131-9137

Method development and validation of a stability-indicating reversed-phase liquid chromatographic method for the simultaneous estimation of metformin and dapagliflozin in presence of their degradation products
By Kotecha, Nidhi; Patel, Jayvadan
From International Journal of Pharmaceutical Sciences Review and Research (2019), 56(2), 1-6.

Validation of a newly developed stability indicating RP-liquid chromatographic method for the quantitative determination of dapagliflozin
By Sura, Sreenivasulu; Modalavalasa, Rameswara Rao; Kothapalli, ChandraSekhar B.
From Pharma Chemica (2018), 10(1), 93-102

Dapagliflozin USP Related Compound A is chemically (2S,3R,4R,5S,6R)-2-[4-Bromo-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (as per USP). It is also known as Dapagliflozin 4-Bromo Analog ; Dapagliflozin Impurity-S3C (Bromo Dapagliflozin). Dapagliflozin USP Related Compound A is supplied with detailed characterization data compliant with regulatory guideline. Dapagliflozin USP Related Compound A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dapagliflozin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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1α-Methoxy Dapagliflozin C-2 Epimer

SZ CAT No:	: SZ-D015086
CAS No	: NA
Mol.F.	: C22H27ClO7
Mol.Wt.	: 438.9
Inv. Status	: Custom Synthesis

Dapagliflozin

SZ CAT No:	: SZ-D015000
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Mol.F.	: C21H25CIO6
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Dapagliflozin 3-O-β-D-glucuronide

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CAS No	: 1351438-75-9
Mol.F.	: C27H33ClO12
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Dapagliflozin USP Related Compound A

SZ CAT No:	: SZ-D015001
CAS No	: 1807632-95-6
Mol.F.	: C21H25BrO6
Mol.Wt.	: 453.3
Inv. Status	: In Stock

Dapagliflozin Bromo Impurity

SZ CAT No:	: SZ-D015007
CAS No	: 461432-23-5
Mol.F.	: C15H14BrClO
Mol.Wt.	: 325.6
Inv. Status	: In Stock

Dapagliflozin Bromo Keto Impurity

SZ CAT No:	: SZ-D015013
CAS No	: 1404477-10-6
Mol.F.	: C15H12BrClO2
Mol.Wt.	: 339.6
Inv. Status	: Custom Synthesis

Dapagliflozin Bromomethanone

SZ CAT No:	: SZ-D015029
CAS No	: 461432-22-4
Mol.F.	: C15H12BrClO2
Mol.Wt.	: 339.6
Inv. Status	: In Stock

Dapagliflozin Citrate

SZ CAT No:	: SZ-D015088
CAS No	: 1848226-91-4
Mol.F.	: C21H25ClO6 : C6H8O7
Mol.Wt.	: 408.9 : 192.1
Inv. Status	: In Stock

Dapagliflozin D4

SZ CAT No:	: SZ-D015D02
CAS No	: 1224234-25-6
Mol.F.	: C21H21D4ClO6
Mol.Wt.	: 412.9
Inv. Status	: Custom Synthesis

Dapagliflozin D5

SZ CAT No:	: SZ-D015D01
CAS No	: 1204219-80-6
Mol.F.	: C21H20D5ClO6
Mol.Wt.	: 413.9
Inv. Status	: In Stock

Dapagliflozin Deschloro Impurity

SZ CAT No:	: SZ-D015003
CAS No	: 2444702-80-9
Mol.F.	: C21H26O6
Mol.Wt.	: 374.4
Inv. Status	: In Stock

Dapagliflozin Dibromo Compound

SZ CAT No:	: SZ-D015015
CAS No	: 1807632-93-4
Mol.F.	: C15H14Br2O
Mol.Wt.	: 370.1
Inv. Status	: In Stock

Dapagliflozin Dimer Impurity

SZ CAT No:	: SZ-D015037
CAS No	: NA
Mol.F.	: C57H62Cl2O20
Mol.Wt.	: 1138.0
Inv. Status	: Custom Synthesis

Dapagliflozin Dimer Impurity (Compound 4)

SZ CAT No:	: SZ-D015044
CAS No	: 2452300-79-5
Mol.F.	: C42H48Cl2O12
Mol.Wt.	: 815.7
Inv. Status	: Custom Synthesis

Dapagliflozin Enantiomeric Impurity

SZ CAT No:	: SZ-D015065
CAS No	: 2459303-35-4
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: Custom Synthesis

Dapagliflozin Furanose Isomer

SZ CAT No:	: SZ-D015031
CAS No	: 1469910-70-0
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Hydroxy Dapagliflozin (USP)

SZ CAT No:	: SZ-D015021
CAS No	: 1204222-85-4
Mol.F.	: C21H25ClO7
Mol.Wt.	: 424.9
Inv. Status	: In Stock

Dapagliflozin Hydroxy Impurity

SZ CAT No:	: SZ-D015032
CAS No	: 960404-86-8
Mol.F.	: C21H25ClO7
Mol.Wt.	: 424.9
Inv. Status	: In Stock

Dapagliflozin Imp.-S2E (Tri acetylated)

SZ CAT No:	: SZ-D015040
CAS No	: 1443341-94-3
Mol.F.	: C27H31ClO9
Mol.Wt.	: 535.0
Inv. Status	: In Stock

Dapagliflozin Impurity 1

SZ CAT No:	: SZ-D015006
CAS No	: 1103738-29-9
Mol.F.	: C15H14ClIO
Mol.Wt.	: 372.6
Inv. Status	: In Stock

Dapagliflozin Impurity 10

SZ CAT No:	: SZ-D015019
CAS No	: NA
Mol.F.	: C42H48Cl2O12
Mol.Wt.	: 815.7
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 11

SZ CAT No:	: SZ-D015020
CAS No	: 2452300-92-2
Mol.F.	: C27H33ClO12
Mol.Wt.	: 585.0
Inv. Status	: Custom Synthesis

O-Desethyl Dapagliflozin

SZ CAT No:	: SZ-D015022
CAS No	: 864070-37-1
Mol.F.	: C19H21ClO6
Mol.Wt.	: 380.8
Inv. Status	: In Stock

Dapagliflozin Impurity 14

SZ CAT No:	: SZ-D015023
CAS No	: 1830346-16-1
Mol.F.	: C15H14BrClO
Mol.Wt.	: 325.6
Inv. Status	: In Stock

Dapagliflozin Impurity 16

SZ CAT No:	: SZ-D015025
CAS No	: NA
Mol.F.	: C31H35ClO12
Mol.Wt.	: 635.1
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 17

SZ CAT No:	: SZ-D015026
CAS No	: 2133407-75-5
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Dapagliflozin Impurity 18

SZ CAT No:	: SZ-D015028
CAS No	: NA
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: Out of Stock

Dapagliflozin Impurity 19

SZ CAT No:	: SZ-D015033
CAS No	: 2133407-73-3
Mol.F.	: C18H23ClOSi
Mol.Wt.	: 318.9
Inv. Status	: Limited Stock

Dapagliflozin Impurity 2

SZ CAT No:	: SZ-D015011
CAS No	: 1280647-32-6
Mol.F.	: C15H14BrClO2
Mol.Wt.	: 341.6
Inv. Status	: In Stock

Dapagliflozin Impurity 20

SZ CAT No:	: SZ-D015034
CAS No	: 1713991-97-9
Mol.F.	: C15H14BrClO2
Mol.Wt.	: 341.6
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 21

SZ CAT No:	: SZ-D015036
CAS No	: 2040305-09-5
Mol.F.	: C29H33ClO10
Mol.Wt.	: 577.0
Inv. Status	: Custom Synthesis

Dapagliflozin-(R)-Furanose

SZ CAT No:	: SZ-D015042
CAS No	: 1469910-83-5
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: Out of Stock

Dapagliflozin Impurity 23

SZ CAT No:	: SZ-D015043
CAS No	: 2452300-78-4
Mol.F.	: C42H48Cl2O12
Mol.Wt.	: 815.7
Inv. Status	: In Stock

Dapagliflozin Impurity 24

SZ CAT No:	: SZ-D015046
CAS No	: NA
Mol.F.	: C42H48Cl2O12
Mol.Wt.	: 815.7
Inv. Status	: Custom Synthesis

Ethyl Dapagliflozin

SZ CAT No:	: SZ-D015049
CAS No	: NA
Mol.F.	: C23H29ClO6
Mol.Wt.	: 436.9
Inv. Status	: In Stock

Dapagliflozin Impurity 28

SZ CAT No:	: SZ-D015050
CAS No	: NA
Mol.F.	: C21H25BrO6 : C3H8O2 : H2O
Mol.Wt.	: 453.3 : 76.1 : 18.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 29

SZ CAT No:	: SZ-D015051
CAS No	: 1415905-91-7
Mol.F.	: C27H31ClO9
Mol.Wt.	: 535.0
Inv. Status	: In Stock

Dapagliflozin Impurity 3

SZ CAT No:	: SZ-D015012
CAS No	: 2176485-21-3
Mol.F.	: C30H28Cl2O2
Mol.Wt.	: 491.5
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 31

SZ CAT No:	: SZ-D015053
CAS No	: 2069934-29-6
Mol.F.	: C15H14Cl2O
Mol.Wt.	: 281.2
Inv. Status	: In Stock

Dapagliflozin Impurity 32

SZ CAT No:	: SZ-D015056
CAS No	: NA
Mol.F.	: C15H14BrClO
Mol.Wt.	: 325.6
Inv. Status	: Custom Synthesis

Dapagliflozin Allose Isomer

SZ CAT No:	: SZ-D015057
CAS No	: 1888296-95-4
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Dapagliflozin Galacto Isomer

SZ CAT No:	: SZ-D015058
CAS No	: 1408245-02-2
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Dapagliflozin Impurity 35

SZ CAT No:	: SZ-D015059
CAS No	: 59748-90-2
Mol.F.	: C7H4BrClO2
Mol.Wt.	: 235.5
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 36

SZ CAT No:	: SZ-D015060
CAS No	: 27003-05-0
Mol.F.	: C7H3Br2ClO2
Mol.Wt.	: 314.4
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 37

SZ CAT No:	: SZ-D015061
CAS No	: 461432-29-1
Mol.F.	: C15H14ClLiO
Mol.Wt.	: 252.7
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 38

SZ CAT No:	: SZ-D015062
CAS No	: 526-95-4
Mol.F.	: C6H12O7
Mol.Wt.	: 196.2
Inv. Status	: In Stock

Dapagliflozin Impurity 39

SZ CAT No:	: SZ-D015063
CAS No	: 864070-18-8
Mol.F.	: C13H10BrClO
Mol.Wt.	: 297.6
Inv. Status	: In Stock

Dapagliflozin Impurity 4

SZ CAT No:	: SZ-D015009
CAS No	: 461432-24-6
Mol.F.	: C22H27ClO7
Mol.Wt.	: 438.9
Inv. Status	: In Stock

Dapagliflozin Impurity 40

SZ CAT No:	: SZ-D015064
CAS No	: 29643-62-7
Mol.F.	: C10H14O
Mol.Wt.	: 150.2
Inv. Status	: In Stock

Dapagliflozin Impurity 41

SZ CAT No:	: SZ-D015066
CAS No	: 66534-31-4
Mol.F.	: C13H11ClO
Mol.Wt.	: 218.7
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 42

SZ CAT No:	: SZ-D015067
CAS No	: NA
Mol.F.	: C19H25ClOSi
Mol.Wt.	: 332.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 43

SZ CAT No:	: SZ-D015068
CAS No	: NA
Mol.F.	: C27H27ClO7
Mol.Wt.	: 499.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 44

SZ CAT No:	: SZ-D015069
CAS No	: NA
Mol.F.	: C12H20O4S
Mol.Wt.	: 260.3
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 45

SZ CAT No:	: SZ-D015070
CAS No	: NA
Mol.F.	: C11H18O4S
Mol.Wt.	: 246.3
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 47

SZ CAT No:	: SZ-D015072
CAS No	: NA
Mol.F.	: C27H36O11
Mol.Wt.	: 536.6
Inv. Status	: Custom Synthesis

Dapagliflozin Peroxide Impurity

SZ CAT No:	: SZ-D015073
CAS No	: 2452300-94-4
Mol.F.	: C21H25ClO8
Mol.Wt.	: 440.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 49

SZ CAT No:	: SZ-D015074
CAS No	: NA
Mol.F.	: C41H46Cl2O12
Mol.Wt.	: 801.7
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 5

SZ CAT No:	: SZ-D015014
CAS No	: NA
Mol.F.	: C21H25BrO6
Mol.Wt.	: 453.3
Inv. Status	: In Stock

Dapagliflozin Impurity 50

SZ CAT No:	: SZ-D015075
CAS No	: NA
Mol.F.	: C22H25ClO5
Mol.Wt.	: 404.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 52

SZ CAT No:	: SZ-D015077
CAS No	: 3029918-94-0
Mol.F.	: C21H23ClO7
Mol.Wt.	: 422.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 53

SZ CAT No:	: SZ-D015078
CAS No	: NA
Mol.F.	: C29H33ClO10
Mol.Wt.	: 577.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 54

SZ CAT No:	: SZ-D015079
CAS No	: 1469910-84-6
Mol.F.	: C29H33ClO10
Mol.Wt.	: 577.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 55

SZ CAT No:	: SZ-D015080
CAS No	: NA
Mol.F.	: C32H33ClO13
Mol.Wt.	: 661.1
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 56

SZ CAT No:	: SZ-D015081
CAS No	: 21900-52-7
Mol.F.	: C7H3BrCl2O
Mol.Wt.	: 253.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 57

SZ CAT No:	: SZ-D015082
CAS No	: NA
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 58

SZ CAT No:	: SZ-D015083
CAS No	: NA
Mol.F.	: C41H47ClO19
Mol.Wt.	: 879.3
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 59

SZ CAT No:	: SZ-D015084
CAS No	: NA
Mol.F.	: C56H62Cl2O19
Mol.Wt.	: 1110.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 60

SZ CAT No:	: SZ-D015085
CAS No	: NA
Mol.F.	: C28H33ClO9
Mol.Wt.	: 549.0
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 61

SZ CAT No:	: SZ-D015087
CAS No	: 2452300-81-9
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 62

SZ CAT No:	: SZ-D015089
CAS No	: 2133407-77-7
Mol.F.	: C22H27ClO7
Mol.Wt.	: 438.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 63

SZ CAT No:	: SZ-D015090
CAS No	: 2173339-31-4
Mol.F.	: C23H29ClO7
Mol.Wt.	: 452.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 64

SZ CAT No:	: SZ-D015091
CAS No	: NA
Mol.F.	: C31H35ClO12
Mol.Wt.	: 635.1
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 65

SZ CAT No:	: SZ-D015092
CAS No	: 2768435-31-8
Mol.F.	: C31H35ClO11
Mol.Wt.	: 619.1
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 66

SZ CAT No:	: SZ-D015094
CAS No	: NA
Mol.F.	: C22H18Br2Cl2O
Mol.Wt.	: 529.1
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 8

SZ CAT No:	: SZ-D015017
CAS No	: NA
Mol.F.	: C22H27ClO7
Mol.Wt.	: 438.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity 9

SZ CAT No:	: SZ-D015018
CAS No	: NA
Mol.F.	: C21H27ClO7
Mol.Wt.	: 426.9
Inv. Status	: In Stock

Dapagliflozin Impurity B

SZ CAT No:	: SZ-D015008
CAS No	: 1662702-90-0
Mol.F.	: C15H15ClO
Mol.Wt.	: 246.7
Inv. Status	: In Stock

Dapagliflozin Impurity D

SZ CAT No:	: SZ-D015010
CAS No	: 1373321-04-0
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Dapagliflozin Impurity S2A

SZ CAT No:	: SZ-D015039
CAS No	: NA
Mol.F.	: C21H25ClO7
Mol.Wt.	: 424.9
Inv. Status	: Custom Synthesis

Dapagliflozin Impurity S3A

SZ CAT No:	: SZ-D015041
CAS No	: NA
Mol.F.	: C28H31ClO9
Mol.Wt.	: 547.0
Inv. Status	: Custom Synthesis

Oxo Dapagliflozin (USP)

SZ CAT No:	: SZ-D015024
CAS No	: 2169998-23-4
Mol.F.	: C21H23ClO7
Mol.Wt.	: 422.9
Inv. Status	: In Stock

Dapagliflozin Methoxy Pyranose Impurity

SZ CAT No:	: SZ-D015004
CAS No	: 714269-57-5
Mol.F.	: C22H27ClO7
Mol.Wt.	: 438.9
Inv. Status	: In Stock

Dapagliflozin Open Ring Impurity

SZ CAT No:	: SZ-D015038
CAS No	: NA
Mol.F.	: C21H27ClO7
Mol.Wt.	: 426.9
Inv. Status	: Custom Synthesis

Dapagliflozin Ortho Isomer

SZ CAT No:	: SZ-D015027
CAS No	: 2040305-05-1
Mol.F.	: C21H25ClO6
Mol.Wt.	: 408.9
Inv. Status	: In Stock

Dapagliflozin Propanediol Monohydrate

SZ CAT No:	: SZ-D015045
CAS No	: 960404-48-2
Mol.F.	: C21H25ClO6 : C3H8O2 : H2O
Mol.Wt.	: 408.9 : 76.1 : 18.0
Inv. Status	: In Stock
Rel. CAS No	: 461432-26-8 (free base) ; 1971128-01-4 (Propanediol)

Dapagliflozin Tetraacetate

SZ CAT No:	: SZ-D015005
CAS No	: 461432-25-7
Mol.F.	: C29H33ClO10
Mol.Wt.	: 577.0
Inv. Status	: In Stock

Dapagliflozin TNG

SZ CAT No:	: SZ-D015030
CAS No	: 714269-58-6
Mol.F.	: C30H35ClO11
Mol.Wt.	: 607.1
Inv. Status	: In Stock

MonoAcetyl Dapagliflozin

SZ CAT No:	: SZ-D015035
CAS No	: 1632287-34-3
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: In Stock

N- Butyl Dapagliflozin Impurity

SZ CAT No:	: SZ-D015055
CAS No	: NA
Mol.F.	: C25H33ClO6
Mol.Wt.	: 465.0
Inv. Status	: Custom Synthesis

O-Pentaacetyl O-Desethyl Dapagliflozin

SZ CAT No:	: SZ-D015054
CAS No	: 912917-85-2
Mol.F.	: C29H31ClO11
Mol.Wt.	: 591.0
Inv. Status	: In Stock

Dapagliflozin USP Related Compound A

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