Bupropion Hydrochloride

SZ CAT No:	SZ-B001001
CAS No	31677-93-7
Mol.F.	C13H18ClNO : HCl
Mol.Wt.	239.7 : 36.5
Inv. Status	In Stock
Rel. CAS No	34911-55-2 (free base) ; 905818-69-1 (HBr salt)
Shipping Condition	Ambient Temperature

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (±)-2-(Tert-Butylamino)-3′-chloropropiophenone hydrochloride (as per USP)

Synonym: Wellbatrin ; Zyban

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(NC(C)(C)C)C(C1=CC=CC(Cl)=C1)=O.Cl

Method development and validation of a novel anti-depressant bupropion by RP-HPLC
By Kumar, Anil; Agrawal, Dilip; Bansal, Mukesh
From Asian Journal of Pharmaceutical Research and Development (2020), 8(3), 211-223

MSn, LC-MS-TOF and LC-PDA studies for identification of new degradation impurities of bupropion
By Bansal, Rohit; Saini, Balraj; Bansal, Yogita; Bansal, Gulshan
From Biomedical Chromatography (2013), 27(11), 1387-1397

Impurities in bupropion hydrochloride sustained-release tablets
By Cheng, Shu-qiao; Cai, Mei; Chen, Min-hui; Wang, Yu
From Zhongnan Yaoxue (2013), 11(2), 89-92

Bupropion Hydrochloride is chemically (±)-2-(Tert-Butylamino)-3′-chloropropiophenone hydrochloride (as per USP). It is also known as Wellbatrin ; Zyban. Bupropion Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Bupropion Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bupropion.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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(3S,5R,6R)-Bupropion Impurity

SZ CAT No:	: SZ-B001031
CAS No	: 2133460-43-0
Mol.F.	: C12H14ClNO3S
Mol.Wt.	: 287.8
Inv. Status	: In Stock

(3S,5S,6S)-Bupropion Impurity

SZ CAT No:	: SZ-B001032
CAS No	: 2133460-42-9
Mol.F.	: C12H14ClNO3S
Mol.Wt.	: 287.8
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(R,R)-Hydroxy Bupropion

SZ CAT No:	: SZ-B001022
CAS No	: 192374-15-5
Mol.F.	: C13H18ClNO2
Mol.Wt.	: 255.8
Inv. Status	: Custom Synthesis
Rel. CAS No	: 233600-54-9 (HCl salt)

(S,S)-Hydroxy Bupropion

SZ CAT No:	: SZ-B001023
CAS No	: 192374-14-4
Mol.F.	: C13H18ClNO2
Mol.Wt.	: 255.8
Inv. Status	: Custom Synthesis
Rel. CAS No	: 106083-71-0 (HCl salt) ; 851615-55-9 (Sulfate salt)

3-Chloropropiophenone

SZ CAT No:	: SZ-B001059
CAS No	: 936-59-4
Mol.F.	: C9H9ClO
Mol.Wt.	: 168.6
Inv. Status	: In Stock

Bupropion USP Related Compound G

SZ CAT No:	: SZ-B001012
CAS No	: 34911-51-8
Mol.F.	: C9H8BrClO
Mol.Wt.	: 247.5
Inv. Status	: In Stock

Bupropion 2'-Chloro Analog (HCl salt)

SZ CAT No:	: SZ-B001010
CAS No	: 1049718-57-1
Mol.F.	: C13H18ClNO : HCl
Mol.Wt.	: 239.7 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1049974-40-4 (Free base)

Bupropion 3,4-Dichloro Impurity

SZ CAT No:	: SZ-B001014
CAS No	: 1346598-72-8
Mol.F.	: C13H17Cl2NO : HCl
Mol.Wt.	: 274.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1193779-34-8 (free base)

Bupropion 3,5-Dichloro Impurity (HCl)

SZ CAT No:	: SZ-B001013
CAS No	: 1346603-00-6
Mol.F.	: C13H17Cl2NO : HCl
Mol.Wt.	: 274.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1193779-48-4 (Free base)

Bupropion Amino Impurity (HCl)

SZ CAT No:	: SZ-B001042
CAS No	: 2227990-16-9
Mol.F.	: C9H10ClNO : HCl
Mol.Wt.	: 183.6 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 119802-69-6 (Free base)

Bupropion D9

SZ CAT No:	: SZ-B001D01
CAS No	: 150988-80-0
Mol.F.	: C13H9D9ClNO
Mol.Wt.	: 248.8
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1189725-26-5 (HCl salt)

Bupropion D9 Hydrochloride

SZ CAT No:	: SZ-B001D04
CAS No	: 1189725-26-5
Mol.F.	: C13H9D9ClNO : HCl
Mol.Wt.	: 248.8 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 150988-80-0 (free base)

Bupropion Des-t-Butylamino Impurity

SZ CAT No:	: SZ-B001009
CAS No	: 34841-35-5
Mol.F.	: C9H9ClO
Mol.Wt.	: 168.6
Inv. Status	: In Stock

Bupropion Hydrochloride

SZ CAT No:	: SZ-B001001
CAS No	: 31677-93-7
Mol.F.	: C13H18ClNO : HCl
Mol.Wt.	: 239.7 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 34911-55-2 (free base) ; 905818-69-1 (HBr salt)

Bupropion Hydroxy Cyclic Impurity

SZ CAT No:	: SZ-B001011
CAS No	: 357399-43-0
Mol.F.	: C13H18ClNO2
Mol.Wt.	: 255.7
Inv. Status	: In Stock
Rel. CAS No	: 866563-95-3 (HCl salt)

Bupropion Impurity 1

SZ CAT No:	: SZ-B001025
CAS No	: NA
Mol.F.	: C12H14ClNO3S
Mol.Wt.	: 287.8
Inv. Status	: Custom Synthesis

Bupropion Impurity 10

SZ CAT No:	: SZ-B001058
CAS No	: 2357953-00-3
Mol.F.	: C9H7Br2ClO
Mol.Wt.	: 326.4
Inv. Status	: Custom Synthesis

Bupropion Impurity 11

SZ CAT No:	: SZ-B001060
CAS No	: NA
Mol.F.	: C14H20ClNO
Mol.Wt.	: 253.8
Inv. Status	: Custom Synthesis

Bupropion Impurity 13

SZ CAT No:	: SZ-B001034
CAS No	: 87427-61-0
Mol.F.	: C9H7BrCl2O
Mol.Wt.	: 282.0
Inv. Status	: In Stock

Bupropion Impurity 14

SZ CAT No:	: SZ-B001035
CAS No	: 92821-91-5
Mol.F.	: C9H7BrCl2O
Mol.Wt.	: 282.0
Inv. Status	: In Stock

Bupropion Impurity 15

SZ CAT No:	: SZ-B001036
CAS No	: 76650-08-3
Mol.F.	: C9H8Br2O
Mol.Wt.	: 292.0
Inv. Status	: In Stock

Bupropion Impurity 16

SZ CAT No:	: SZ-B001037
CAS No	: 99846-93-2
Mol.F.	: C9H8Cl2O
Mol.Wt.	: 203.1
Inv. Status	: Custom Synthesis

Bupropion Impurity 17

SZ CAT No:	: SZ-B001061
CAS No	: NA
Mol.F.	: C13H16ClNO2
Mol.Wt.	: 253.7
Inv. Status	: Custom Synthesis

Bupropion Impurity 18

SZ CAT No:	: SZ-B001062
CAS No	: 1623052-09-4
Mol.F.	: C13H16ClNO
Mol.Wt.	: 237.7
Inv. Status	: Custom Synthesis

Bupropion Impurity 19

SZ CAT No:	: SZ-B001063
CAS No	: 2700324-50-9
Mol.F.	: C12H14ClNO3S
Mol.Wt.	: 287.8
Inv. Status	: Custom Synthesis

Bupropion Impurity 2

SZ CAT No:	: SZ-B001026
CAS No	: 92821-92-6
Mol.F.	: C9H8Cl2O
Mol.Wt.	: 203.1
Inv. Status	: In Stock

Bupropion Impurity 3

SZ CAT No:	: SZ-B001027
CAS No	: 6323-18-8
Mol.F.	: C9H9ClO
Mol.Wt.	: 168.6
Inv. Status	: Custom Synthesis

Bupropion Impurity 4

SZ CAT No:	: SZ-B001021
CAS No	: 1246812-57-6
Mol.F.	: C12H14ClNO3S
Mol.Wt.	: 287.8
Inv. Status	: Custom Synthesis

Bupropion Impurity 6

SZ CAT No:	: SZ-B001054
CAS No	: 2748533-28-8
Mol.F.	: C13H17Cl2NO : HCl
Mol.Wt.	: 274.2 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2748533-27-7 (free base)

Bupropion Impurity 7

SZ CAT No:	: SZ-B001055
CAS No	: NA
Mol.F.	: C13H17Cl2NO
Mol.Wt.	: 274.2
Inv. Status	: Custom Synthesis
Rel. CAT No	: SZ-B001030 ,

Bupropion Impurity 8

SZ CAT No:	: SZ-B001056
CAS No	: 877-37-2
Mol.F.	: C9H8BrClO
Mol.Wt.	: 247.5
Inv. Status	: In Stock

Bupropion Impurity 9

SZ CAT No:	: SZ-B001057
CAS No	: 103175-61-7
Mol.F.	: C9H7BrCl2O
Mol.Wt.	: 282.0
Inv. Status	: Custom Synthesis

N-Nitroso Bupropion

SZ CAT No:	: SZ-B001020
CAS No	: 2763780-10-3
Mol.F.	: C13H17ClN2O2
Mol.Wt.	: 268.7
Inv. Status	: In Stock

Bupropion Related Compound D Hydrochloride

SZ CAT No:	: SZ-B001005
CAS No	: 63199-74-6
Mol.F.	: C13H19NO : HCl
Mol.Wt.	: 205.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 34509-36-9 (Free base)

Bupropion Related Compound E

SZ CAT No:	: SZ-B001006
CAS No	: 10557-17-2
Mol.F.	: C9H7ClO2
Mol.Wt.	: 182.6
Inv. Status	: In Stock

Bupropion USP Related Compound A Hydrochloride

SZ CAT No:	: SZ-B001002
CAS No	: 1049718-72-0
Mol.F.	: C13H18ClNO : HCl
Mol.Wt.	: 239.7 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 252193-58-1 (Free base)

Bupropion USP Related Compound B Hydrochloride

SZ CAT No:	: SZ-B001003
CAS No	: 1049718-43-5
Mol.F.	: C13H18BrNO : HCl
Mol.Wt.	: 284.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1049974-35-7 (Free base)

Bupropion USP Related Compound C

SZ CAT No:	: SZ-B001004
CAS No	: 152943-33-4
Mol.F.	: C9H9ClO2
Mol.Wt.	: 184.6
Inv. Status	: In Stock

Bupropion USP Related Compound F

SZ CAT No:	: SZ-B001007
CAS No	: 857233-13-7
Mol.F.	: C9H9ClO2
Mol.Wt.	: 184.6
Inv. Status	: In Stock

(1S,2R)-Erythro-Dihydro Bupropion

SZ CAT No:	: SZ-B001015
CAS No	: 102141-11-7
Mol.F.	: C13H20ClNO
Mol.Wt.	: 241.8
Inv. Status	: Custom Synthesis
Rel. CAS No	: 357637-16-2 (HCl salt)

Erythrohydro Bupropion D9

SZ CAT No:	: SZ-B001D07
CAS No	: 2140262-49-1
Mol.F.	: C13H11D9ClNO
Mol.Wt.	: 250.8
Inv. Status	: Custom Synthesis

Hydroxy Bupropion D6

SZ CAT No:	: SZ-B001D02
CAS No	: 1216893-18-3
Mol.F.	: C13H12D6ClNO2
Mol.Wt.	: 261.8
Inv. Status	: Custom Synthesis

Hydroxy Bupropion D8

SZ CAT No:	: SZ-B001D03
CAS No	: 1309283-18-8
Mol.F.	: C13H10D8ClNO2
Mol.Wt.	: 263.8
Inv. Status	: Custom Synthesis

Hydroxybupropion D6

SZ CAT No:	: SZ-B001D05
CAS No	: 1184984-06-2
Mol.F.	: C13H12D6ClNO2
Mol.Wt.	: 261.8
Inv. Status	: Custom Synthesis

Hydroxybupropion Hydrochloride

SZ CAT No:	: SZ-B001053
CAS No	: 78800-56-3
Mol.F.	: C13H18ClNO2 : HCl
Mol.Wt.	: 255.8 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 92264-81-8 (free base)

m-Chlorobenzoic Acid

SZ CAT No:	: SZ-B001017
CAS No	: 535-80-8
Mol.F.	: C7H5ClO2
Mol.Wt.	: 156.6
Inv. Status	: In Stock
Rel. CAS No	: 17264-88-9 (Na salt) ; 16518-11-9 (K salt)
Rel. CAT No	: SZ-B001048 , SZ-B001049 ,

N-Nitroso Bupropion 2'-Chloro Analog

SZ CAT No:	: SZ-B001064
CAS No	: NA
Mol.F.	: C13H17ClN2O2
Mol.Wt.	: 268.7
Inv. Status	: Custom Synthesis

N-Nitroso Bupropion 3,4-Dichloro Impurity

SZ CAT No:	: SZ-B001067
CAS No	: NA
Mol.F.	: C13H16Cl2N2O2
Mol.Wt.	: 303.2
Inv. Status	: In Stock

N-Nitroso Bupropion 3,5-Dichloro Impurity

SZ CAT No:	: SZ-B001068
CAS No	: NA
Mol.F.	: C13H16Cl2N2O2
Mol.Wt.	: 303.2
Inv. Status	: Custom Synthesis

N-Nitroso Bupropion USP Related Compound A

SZ CAT No:	: SZ-B001065
CAS No	: NA
Mol.F.	: C13H17ClN2O2
Mol.Wt.	: 268.7
Inv. Status	: In Stock

N-Nitroso Bupropion USP Related Compound B

SZ CAT No:	: SZ-B001066
CAS No	: NA
Mol.F.	: C13H17BrN2O2
Mol.Wt.	: 313.2
Inv. Status	: In Stock

Threo Hydroxy Bupropion

SZ CAT No:	: SZ-B001016
CAS No	: 153365-82-3
Mol.F.	: C13H20ClNO
Mol.Wt.	: 241.8
Inv. Status	: Custom Synthesis
Rel. CAS No	: 357637-18-4 (HCl salt)

Threohydro Bupropion D9

SZ CAT No:	: SZ-B001D06
CAS No	: 2747918-82-5
Mol.F.	: C13H11D9ClNO
Mol.Wt.	: 250.8
Inv. Status	: Custom Synthesis

Bupropion Hydrochloride

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