Chemical Name: 5-Bromo-N-1H-imidazol-2-yl-6-quinoxalinamine ;
Synonym: 4,5-Didehydro Brimonidine
Smiles: BrC1=C2N=CC=NC2=CC=C1NC3=NC=CN3
Inchi: InChI=1S/C9H8BrN5.C2HF3O2/c10-7-5(15-9(11)12)1-2-6-8(7)14-4-3-13-6;3-2(4,5)1(6)7/h1-4H,(H4,11,12,15);(H,6,7)
Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma
B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.Prausnitz
Journal of Controlled Release Volume 228, 28 April 2016, Pages 48-57
Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma
Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun
ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999
A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems
Jianguo Sun, Xiuwen Zhang & Taomin Huang
Chemistry Central Journal volume 11, Article number: 62 (2017)
Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Brimonidine Tartrate in Pure Form, Formulations and Preformulation Studies
Prakash Bhagav 1, Pandurang Deshpande 1, Saurabh Pandey 1 , Sajeev Chandran
Der Pharmacia Lettre, 2010, 2(3): 106-122