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Blog archive

2020
2021

Bortezomib

Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The boron atom in bortezomib binds the catalytic site of the 26S proteasome with high affinity and specificity. In May 2003, bortezomib became the first anticancerproteasome inhibitor that was approved by the FDA.

Bupropion

Bupropion is an aminoketone with antidepressant activity. Bupropion is a unicyclic aminoketone that belongs to the class of substituted cathinones and the more general class of substituted phenethylamines. Bupropion is a medication primarily used to treat major depressivedisorder and to support smokingcessation. It was approved by the USFDA as an antidepressant.

Budesonide

Budesonide is used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. Budesonide belongs to the class of organiccompounds known as 21-hydroxysteroids. During the 2020 COVID-19 pandemic, researchers observed that patients already prescribed inhaled corticosteroids appeared to develop less serious illness when diagnosed with covid19

Brivaracetam

Brivaracetam is an orally bioavailable levetiracetam derivative, with anticonvulsant activity. Brivaracetam is used in the treatment of partial-onset seizures. Brivaracetam was approval on February 19, 2016.

Brexpiprazole

Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. Brexpiprazole is an atypical antipsychotic used in the treatment of schizophrenia and major depressivedisorders. In January 2018, it was approved .

Bosutinib

Bosutinib is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Bosutinib is a Bcr-Abl kinase inhibitor for the treatment of Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Bosutinib was approved on September 4, 2012.

Ampicillin

Ampicillin is a broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidalactivity. Ampicillin is an antibiotic used to prevent and treat a number of bacterialinfections, such as infections, urinary, meningitis, salmonellosis, and endocarditis. Ampicillin was discovered in 1958 and came into commercial use in 1961.

Almotriptan

Almotriptan is a sulfonamide triptan with extracerebral, intracranial vasoconstrictor activity. Almotriptan is a triptan drug for the treatment of migraineheadaches. It was patented in 1992 and approved for medical use in 2000.

Amoxicillin

Amoxicillin belongs to the class of organiccompounds known as penicillins. Amoxicillin is an antibiotic used to treat a number of bacterialinfections. These include middle earinfection, strepthroat, pneumonia, skininfections, and urinarytractinfections among others. Amoxicillin was discovered in 1958 and came into medical use in 1972. Amoxicillin is available from 2017.

Aprepitant

Aprepitant an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents. Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It was approved by the Food and Drug Administration (FDA) in 2003. In 2008, fosaprepitant, an intravenous form of Aprepitant was approved.