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Blog archive

2020

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2021

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2022

January (4)

February (3)

March (5)

April (5)

May (1)

Fluocinolone

Date Thursday, April 28, 2022 /

Fluocinolone binds the glucocorticoid receptor, followed by translocation of the ligand-receptor complex to the nucleus and transcription activation of genes containing glucocorticoid-responsive elements. Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization. It was patented in 1958 and approved for medical use in 1961.

 

SynZeal offers allFluocinolone related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Fluocinolone related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

 

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Fesoterodine

Date Friday, April 22, 2022 /

Fesoterodine also known as toviaz, belongs to the class of organic compounds known as diphenylmethanes. Fesoterodine is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. It was approved by the European Medicines Agency in April 2007

 

SynZeal offers all  Fesoterodine related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Fesoterodine related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

 

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Exemestane

Date Thursday, April 14, 2022 /

Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Exemestane is a drug which is used for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. FDA approval was in October 2005.

 

SynZeal offers allExemestane related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Exemestane related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

 

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Ezetimibe

Date Friday, April 8, 2022 /

Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous sitosterolemia (phytosterolemia). Ezetimibe was approved for medical use in the United States in 2002.

 

SynZeal offers allEzetimibe related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Ezetimibe related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

 

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Etonogestrel

Date Thursday, March 31, 2022 /

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.Etonogestrel is a drug which is used for use as a female contraceptive. Etonogestrel was patented in 1972 and introduced for medical use in 1998.

 

SynZeal offers all  Etonogestrel related impurities standards with certified COA and characterization data like IR, Mass, HPLC, purity, NMR & TGA report. We also provide CMR, DEPT and detailed structure characterization report as per requirements. Etonogestrel related standards are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.

 

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