Bisoprolol EP Impurity G

SZ CAT No:	SZ-B003008
CAS No	NA
Mol.F.	C19H33NO5 : 1/2(C4H4O4)
Mol.Wt.	355.5 : 1/2(116.1)
Inv. Status	In Stock
Rel. CAS No	1215342-36-1 (free base)
Shipping Condition	Ambient Temperature

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Chemical Name: (2RS)-1-[4-[[(2-isopropoxyethoxy)methoxy]methyl]phenoxy]-3-isopropylaminopropan-2-ol fumarate (2:1) (as per EP) ; (1-(4-{[(2-Isopropoxyethoxy)methoxy]methyl}phenoxy)-3-(isopropylamino)propan-2-ol fumarate (2:1) salt (as per USP)

Synonym: Bisoprolol USP Related Compound D

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC(CNC(C)C)COC1=CC=C(COCOCCOC(C)C)C=C1.OC(/C=C/C(O)=O)=O

High-performance liquid chromatographic method for the determination of bisoprolol and potential impurities
Nelly N. Agapova*,Elissaveta Vasileva
Journal of Chromatogrkphy A, 654 (1993) 299-352

Investigation of the retention mechanisms of amlodipine besylate, bisoprolol fumarate, and their impurities on three different HILIC columns
Irena Kasagić-Vujanović, Biljana Jančić-Stojanović & Darko Ivanović
Journal of liquid chromatography & related technologies 2018, vol. 41, no. 9, 523–531

Robust UHPLC Separation Method Development for Multi‑API Product Containing Amlodipine and Bisoprolol: The Impact of Column Selection
Róbert Kormány, Imre Molnár, Jenő Fekete, Davy Guillarme & Szabolcs Fekete
Chromatographia volume 77, pages1119–1127(2014)

Stability-Indicating RP-HPLC and CE Methods for Simultaneous Determination of Bisoprolol and Perindopril in Pharmaceutical Formulation: A Comparative Study
Said A. Hassan, Nancy W. Nashat *, Mohamed R. Elghobashy, Samah S. Abbas and Azza A. Moustafa
Journal of Chromatographic Science, Volume 58, Issue 8, September 2020, Pages 747–758

Bisoprolol EP Impurity G is chemically (2RS)-1-[4-[[(2-isopropoxyethoxy)methoxy]methyl]phenoxy]-3-isopropylaminopropan-2-ol fumarate (2:1) (as per EP) ; (1-(4-{[(2-Isopropoxyethoxy)methoxy]methyl}phenoxy)-3-(isopropylamino)propan-2-ol fumarate (2:1) salt (as per USP). It is also known as Bisoprolol USP Related Compound D. Bisoprolol EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Bisoprolol EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bisoprolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-B003047
CAS No	: 66722-44-9
Mol.F.	: C18H31NO4
Mol.Wt.	: 325.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 104344-23-2 (fumarate salt)
Rel. CAT No	: SZ-B003001 ,

SZ CAT No:	: SZ-B003005
CAS No	: 1225195-71-0
Mol.F.	: C26H40N205
Mol.Wt.	: 460.6
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAT No	: SZ-B003048 ,

SZ CAT No:	: SZ-B003048
CAS No	: NA
Mol.F.	: C26H40N2O5 : 2(C2HF3O2)
Mol.Wt.	: 460.6 : 2(114.0)
Inv. Status	: Limited Stock
Rel. CAS No	: 1225195-71-0 (TFA salt)
Rel. CAT No	: SZ-B003005 ,

SZ CAT No:	: SZ-B003011
CAS No	: 29122-74-5
Mol.F.	: C13H19NO3
Mol.Wt.	: 237.3
Inv. Status	: In Stock
Rel. CAS No	: 1956321-87-1 (HCl salt) ; 1639933-77-9 (Oxalate sat)
Rel. CAT No	: SZ-M021007 ,

SZ CAT No:	: SZ-B003001
CAS No	: 104344-23-2
Mol.F.	: C18H31NO4 : 1/2(C4H4O4)
Mol.Wt.	: 325.4 : 1/2(116.1)
Inv. Status	: In Stock
Rel. CAS No	: 66722-44-9 (free base)
Rel. CAT No	: SZ-B003047 ,

Bisoprolol EP Impurity G

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SZ CAT No:	: SZ-B003030
CAS No	: 109-59-1
Mol.F.	: C5H12O2
Mol.Wt.	: 104.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003D01
CAS No	: 298704-22-0
Mol.F.	: C7HD5O2
Mol.Wt.	: 127.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B003017
CAS No	: 623-05-2
Mol.F.	: C7H8O2
Mol.Wt.	: 124.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003046
CAS No	: NA
Mol.F.	: C13H21NO3 : C4H4O4
Mol.Wt.	: 239.3 : 116.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2290571-50-3 (free base)

SZ CAT No:	: SZ-B003020
CAS No	: NA
Mol.F.	: C13H18LiNO4
Mol.Wt.	: 259.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 72570-70-8 (free base)

SZ CAT No:	: SZ-B003D03
CAS No	: NA
Mol.F.	: C18H26D5NO4
Mol.Wt.	: 330.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B003D02
CAS No	: 2140803-85-4
Mol.F.	: C18H26D5NO4 : C4H4O4
Mol.Wt.	: 330.5 : 116.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1189881-87-5 (free base)

SZ CAT No:	: SZ-B003035
CAS No	: NA
Mol.F.	: C19H29NO2
Mol.Wt.	: 303.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B003023
CAS No	: 2775292-22-1
Mol.F.	: C33H53NO8
Mol.Wt.	: 591.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003002
CAS No	: 62572-93-4
Mol.F.	: C13H21NO3
Mol.Wt.	: 239.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003003
CAS No	: 1447715-44-7
Mol.F.	: C18H31NO4
Mol.Wt.	: 325.4
Inv. Status	: In Stock

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CAS No	: 1797132-90-1
Mol.F.	: C25H38N2O4
Mol.Wt.	: 430.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003006
CAS No	: 1217245-60-7
Mol.F.	: C18H29NO3
Mol.Wt.	: 307.4
Inv. Status	: Out of Stock, Custom Synthesis

SZ CAT No:	: SZ-B003007
CAS No	: 1798418-82-2
Mol.F.	: C18H31NO4
Mol.Wt.	: 325.4
Inv. Status	: In Stock
Rel. CAS No	: 2470233-28-2 (Fumarate salt)

SZ CAT No:	: SZ-B003008
CAS No	: NA
Mol.F.	: C19H33NO5 : 1/2(C4H4O4)
Mol.Wt.	: 355.5 : 1/2(116.1)
Inv. Status	: In Stock
Rel. CAS No	: 1215342-36-1 (free base)

SZ CAT No:	: SZ-B003009
CAS No	: 1797024-50-0
Mol.F.	: C15H24O5
Mol.Wt.	: 284.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003010
CAS No	: 864544-37-6
Mol.F.	: C18H29NO5
Mol.Wt.	: 339.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003012
CAS No	: 177034-57-0
Mol.F.	: C12H18O3
Mol.Wt.	: 210.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003013
CAS No	: 1346601-75-9
Mol.F.	: C17H29NO4
Mol.Wt.	: 311.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003014
CAS No	: 1346604-00-9
Mol.F.	: C16H27NO4
Mol.Wt.	: 297.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003015
CAS No	: 5790-46-5
Mol.F.	: C13H21NO2
Mol.Wt.	: 223.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003016
CAS No	: 123-08-0
Mol.F.	: C7H6O2
Mol.Wt.	: 122.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003024
CAS No	: 1173203-26-3
Mol.F.	: C14H17NO4
Mol.Wt.	: 263.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003025
CAS No	: 1071765-44-0
Mol.F.	: C14H19NO4
Mol.Wt.	: 265.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003018
CAS No	: 66722-57-4
Mol.F.	: C15H22O4
Mol.Wt.	: 266.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003034
CAS No	: 1346601-19-1
Mol.F.	: C15H23NO5
Mol.Wt.	: 297.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003019
CAS No	: 4204-78-8
Mol.F.	: C10H12O3
Mol.Wt.	: 180.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003021
CAS No	: 1346603-05-1
Mol.F.	: C15H20O5
Mol.Wt.	: 280.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B003039
CAS No	: 2469273-10-5
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B003041
CAS No	: NA
Mol.F.	: C19H33NO4
Mol.Wt.	: 339.5
Inv. Status	: Custom Synthesis