All Categories
  • All Categories
  • Accessories
  • Accessories & More
  • Butters & Eggs
  • Camera & Video
  • Mornitors
  • Tablets
  • Laptops
  • Handbags
  • Headphone & Speaker
  • Herbs & botanicals
  • Vegetables
  • Shop
  • Laptops & Desktops
  • Watchs
  • Electronic

Apixaban Impurity 12

SZ CAT No SZ-A062023
CAS No NA
Mol.F. C40H34N10O7 
Mol.Wt. 766.8
Inv. Status Custom Synthesis


Chemical Name: (E)-1,2-Bis(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)phenyl)diazene 1-oxide

Smiles: O=C(N(C1=CC=C(/N=[N+]([O-])\C2=CC=C(C=C2)N(CC3)C(C4=C3C(C(N)=O)=NN4C5=CC=C(OC)C=C5)=O)C=C1)CC6)C7=C6C(C(N)=O)=NN7C8=CC=C(OC)C=C8

Inchi: InChI=1S/C29H31N5O5/c1-38-23-11-9-22(10-12-23)34-27-24(26(30-34)28(36)31-16-18-39-19-17-31)13-15-33(29(27)37)21-7-5-20(6-8-21)32-14-3-2-4-25(32)35/h5-12H,2-4,13-19H2,1H3

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
 
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
 
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785
 
Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1  · Nathalie Ribeiro Wingert1  · Nadia Maria Volpato1  · Cássia Virginia Garcia1  · Elfrides E. S. Schapoval1  · Martin Steppe
Chromatographia volume 83, pages65–75(2020)