Abemaciclib Impurity 12

SZ CAT No:	SZ-A077017
CAS No	1648707-16-7
Mol.F.	C21H20F2N6O
Mol.Wt.	410.4
Inv. Status	In Stock

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Chemical Name: (6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC1=C(C2=CC(F)=C3C(N(C(C)C)C(C)=N3)=C2)N=C(NC4=CC=C(CO)C=N4)N=C1

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

Abemaciclib Impurity 12 is chemically (6-((5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol. Abemaciclib Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Abemaciclib Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Abemaciclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Abemaciclib Impurity 12

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