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Blog archive

2020
2021

Daclatasvir

Daclatasvir is an orally available inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A) replication complex, with potential activity against HCV. Daclatasvir use with Sofosbuvir with or without Ribavirin to treat HCV genotype 1 and 3 infections. Daclatasvir was FDA-approved in July 2015.

Dabigatran

Dabigatran is a direct inhibitor of thrombin and anticoagulant which is used for prevention of stroke and venous embolism in patients with chronic atrial fibrillation. Dabigatran was approved for medical use in 2010.

Cyanocobalamin

Cyanocobalamin is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria, and is necessary for DNA synthesis and cellular energy production. In the cobalamins, cobalt normally exists in the trivalent state, Co(III). However, under reducing conditions, the cobalt centre is reduced to Co(II) or even Co(I), which are usually denoted as B12r and B12s, for reduced and super reduced, respectively.

Dabigatran

Dabigatran is a direct inhibitor of thrombin and anticoagulant which is used for prevention of stroke and venous embolism in patients with chronic atrial fibrillation. Dabigatran was approved for medical use in 2010.

Colchicine

Colchicine is an alkaloid isolated from Colchicum autumnale with anti-gout and anti-inflammatory activities. colchicine is an alkaloid drug commonly used in the management of gout; a condition associated with the painful deposition of urate crystals in the joints.

Colesevelam

Colesevelam Hydrochloride is a hydrochloride salt form of colesevelam, a non-absorbed polymer that binds bile acids in the intestine and lowers serum lipids. Colesevelam is used with exercise and diet changes to reduce the amount of cholesterol and certain fatty substances in the blood.

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It is used to treat various skin disorders, including eczema and psoriasis. It has a role as an anti-inflammatory drug.

Clarithromycin

Clarithromycin a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections.

Cisatracurium

Cisatracurium is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine.