Dibenzo Cycloheptene

Determination of Degradation Products of Cyclobenzaprine Hydrochloride, Lidocaine and Piroxicam in a Semi-Topical Formulation: MS–MS Confirmation of Unknown Impurities
Bogdan Ionel Cioroiu1,*, Ioana Cezara Grigoriu2, Mona Elisabeta Cioroiu3, Marius Niculaua4, Roxana Lupuleasa5, and Mihai Ioan Lazar
Journal of Chromatographic Science, 2016, Vol. 54, No. 6, 902–911
 
Separation of cyclobenzaprine from biological samples and its determination by thin-layer chromatography followed by densitometry
D.B.Faber
Journal of Chromatography A Volume 74, Issue 1, 6 December 1972, Pages 85-98
 
Development and Validation of Three Spectrophotometric Methods for Determination of Cyclobenzaprine Hcl in The Presence of its Two Major Degradation Products
Ibrahim A. Naguib, Eglal A. Abdelaleem, Fatma F. Abdallah & Nouruddin W. Ali
Analytical Chemistry Letters Volume 6, 2016 - Issue 1 Pages 24-34.

Dibenzo Cycloheptene is chemically 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene ; Dibenzosuberane ; NSC 86156. It is also known as Suberane. Dibenzo Cycloheptene is supplied with detailed characterization data compliant with regulatory guideline. Dibenzo Cycloheptene can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cyclobenzaprine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.