Pazopanib Impurity 28

SZ目录编号:	SZ-P013042
CAS 号	2369664-17-3
分子式	C24H26N8
分子量	426.5
投资状态	Custom Synthesis
Rel. CAS No	2765801-03-2 (HCl salt)

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化学名称: N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N2,N4-dimethylpyrimidine-2,4-diamine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: CC1=C(C=C2)C(C=C2N(C3=NC(N(C(C=CC4=C5C)=CC4=NN5C)C)=NC=C3)C)=NN1C

Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S Kord
J Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.

Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu
Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102

Characterization of forced degradation products of pazopanib hydrochloride by UHPLC‐Q‐TOF/MS and in silico toxicity prediction
Prinesh N. Patel Pradipbhai D. Kalariya Mahesh Sharma Prabha Garg M. V. N Kumar Talluri S. Gananadhamu R. Srinivas
Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928

Development and validation of a stability indicating RP-HPLC method for the determination of Pazopanib in bulk drug and its pharmaceutical dosage form
Kishore Kumar Reddy Y, J. Raveendra Reddy and N. Devanna
J. Chem. Pharm. Res., 2015, 7(9):127-132

Validated RP-HPLC Method Development of Pazopanib in Bulk and its Pharmaceutical Dosage Form
Kiran Kumar Buralla, and Varadarajan Parthasarathy
Pharmaceutical Methods,2020,11,1,21-24.

Pazopanib Impurity 28 is chemically N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N2,N4-dimethylpyrimidine-2,4-diamine. Pazopanib Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Pazopanib Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pazopanib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Pazopanib Impurity 28

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