Fosaprepitant Impurity 16

SZ目录编号:	SZ-F017037
CAS 号	NA
分子式	C23H22F7N4O7P : C7H17NO5
分子量	630.4 : 195.2
投资状态	Custom Synthesis
Rel. CAS No	1350288-79-7 (free base)

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化学名称: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl phosphate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: O=P(O)(O)ON1NC(CN2[C@H](C3=CC=C(F)C=C3)[C@H](O[C@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)OCC2)=NC1=O.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC

GC-FID technique for the quantitative evaluation of multiple residual organic solvent impurities in fosaprepitant dimeglumine drug
By Reddy, H. Ramakrishna; Pratap, S. R.; Chandrasekhar, N.; Shamshuddin, S. Z. M.
From Asian Journal of Chemistry (2021), 33(7), 1645-1650

Quantification and method validation of dicyclohexylurea content in fosaprepitant dimeglumine drug substance by reverse phase HPLC
By Kishore, M. V.; Sivarao, T.; Srinivas, K. Rama; Satyendranath, Ch. V.; Kumar, Vundavilli Jagadeesh; Kumar, K. S. R. Pavan; Sreenivas, N.
From International Journal of Pharmaceutical Sciences and Research (2020), 11(10), 5010-5016

Quality by design approach for development and validation of stability indicating RP-HPLC method for fosaprepitant dimeglumine
By Shaikh, Jalil K.; Farooqui, Mazahar; Syed, Ummul Khair Asema
From Asian Journal of Chemistry (2020), 32(9), 2158-2164

Fosaprepitant Impurity 16 is chemically (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl phosphate. Fosaprepitant Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 16

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