Anastrozole HCl

SZ目录编号:	SZ-A003031
CAS 号	868771-60-2
分子式	C17H19N5 : HCl
分子量	293.4 : 36.5
投资状态	Custom Synthesis
Rel. CAS No	120511-73-1 (free base) ; 876514-43-1 (HBr salt)

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化学名称: 2,2′-[5-(1H-1,2,4-Triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile) hydrochloride(As per EP) α,α,α′,α′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile hydrochloride(as per USP)

异名: Anastrozolum ; Anastrol ; Arimidex

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: CC(C)(C#N)C1=CC(CN2N=CN=C2)=CC(C(C)(C#N)C)=C1.Cl

LC and LC–MS/MS study of forced decomposition behavior of anastrozole and establishment of validated stability-indicating analytical method for impurities estimation in low dose anastrozole tablets
Y. Ramachandra Reddy b,∗, Srinivasan R. Nandana,b,∗∗, D. Vijaya Bharathi c, B. Nagarajua, S. Saidu Reddy b, L.K. Ravindranathb, V. Suryanarayan Rao b
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 397–404

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
Yusra A Alyafee,1,2 Manal Alaamery,1 Shahad Bawazeer,1 Mansour S Almutairi,1 Badr Alghamdi,1 Nawaf Alomran,1 Atia Sheereen,1 Maha Daghestani,2 and Salam Massadeh1,3
Int J Nanomedicine. 2018; 13: 199–208.

Isolation and characterization of process related impurities in anastrozole active pharmaceutical ingredient
S. G. Hiriyanna*; K. Basavaiah
J. Braz. Chem. Soc., Vol. 19, No. 3, 397-404, 2008.

Anastrozole HCl is chemically 2,2′-[5-(1H-1,2,4-Triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile) hydrochloride(As per EP) α,α,α′,α′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile hydrochloride(as per USP). It is also known as Anastrozolum ; Anastrol ; Arimidex. Anastrozole HCl is supplied with detailed characterization data compliant with regulatory guideline. Anastrozole HCl can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Anastrozole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Anastrozole HCl

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