Caffeine

Application of a column classification method in a selectivity study involving caffeine and its related impurities
Jaros"aw Szulfer a , Alina Plenis b , Tomasz Ba˛czek
Talanta Volume 99, 15 September 2012, Pages 492-501
 
An hplc method for the determination of vitamin b1, caffeine, acetylsalicylic acid, and the impurities of salicylic acid in a pharmaceutical preparation
L. Gamiz-Gracia, M. D. Luque de Castro"
J. liq. chrom. & rel. technol., 20(13), 2123-2133 (1997)
 
Rapid Spectrophotometric Determination of Caffeine
N. H. Ishler, T. P. Finucane, and Emanuel. Borker
Anal. Chem. 1948, 20, 12, 1162–1166
 
Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods
Hany Ibrahim 1,*, Abdallah M. Hamdy 1,*, Hanan A. Merey2,3 and Ahmed S. Saad
Journal of Chromatographic Science, Volume 59, Issue 2, February 2021, Pages 140–147

Caffeine is chemically 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione ; 1,3,7-Trimethylxanthine ; 7-Methyltheophylline. It is also known as Theophylline EP Impurity A ; Pentoxifylline EP Impurity F. Caffeine is supplied with detailed characterization data compliant with regulatory guideline. Caffeine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Caffeine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.