Brexpiprazole Hydrobromide

SZ CAT No:	SZ-B011023
CAS No	1427049-36-2
Mol.F.	C25H27N3O2S : HBr
Mol.Wt.	433.6 : 80.9
Inv. Status	Custom Synthesis
Rel. CAS No	1420987-74-1 (HCl salt) ; 913611-97-9 (free base) ; 913612-39-2 (Sulfate salt)

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Chemical Name: 7-[4-(4-Benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone Hydrobromide; 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one Hydrobromide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1NC2=CC(OCCCCN3CCN(C4=C(C=CS5)C5=CC=C4)CC3)=CC=C2C=C1.Br

Development and validation of stability indicating RP-HPLC method for estimation of Brexpiprazole in tablet
By Jaiswal, Chandrakant C.; Patel, Harsha U.
From World Journal of Pharmacy and Pharmaceutical Sciences (2020), 9(6), 1568-1582

Stability indicating TLC method for quantification of Brexpiprazole in bulk and its pharmaceutical dosage form and determination of content uniformity
By Thakkar, Anjali M.; Chhalotiya, Usmangani K.; Parekh, Nikunj; Desai, Jaineel V.; Shah, Dimal A.
From Journal of Chromatographic Science (2019), 57(7), 644-652

A new stability indicating RP-HPLC method for estimation of brexpiprazole
By Kumar, Vanapalli Goutham; Mondal, Sumanta
From Journal of Drug Delivery and Therapeutics (2019), 9(2Suppl.), 214-222

Brexpiprazole Hydrobromide is chemically 7-[4-(4-Benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone Hydrobromide; 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one Hydrobromide. Brexpiprazole Hydrobromide is supplied with detailed characterization data compliant with regulatory guideline. Brexpiprazole Hydrobromide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Brexpiprazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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