Promethazine Sulfone

Chromatographic determination of promethazine hydrochloride in aqueous solution
B. J. Meakin,   D. J. G. Davies,   Norma Cox  and  John Stevens 
Analyst, 1976,101, 720-727
 
Determination of thiazinamium, promazine and promethazine in pharmaceutical formulations using a CZE method
Francisco J. Lara, Ana M. Garc´ıa-Campana˜ ∗, Ferm´ın Ales-Barrero, ´ Juan M. Bosque-Sendra
Analytica Chimica Acta Volume 535, Issues 1–2, 11 April 2005, Pages 101-108
 
Stability Indicating RP-HPLC Method Development for Related Substances of Anti-Histamine Promethazine Hydrochloride and its Validation Study.
Nilesh Takale, Neelakandan Kaliyaperumal, Gopal Krishnan, Mannathusamy and Raja Rajan Govindasamy
Orient. J. Chem., Vol. 36(5), 889-896 (2020)
 
Identification and determination of ketotifen hydrogen fumarate, azelastine hydrochloride, dimetindene maleate and promethazine hydrochloride by densitometric method.
Wyszomirska E1, Czerwińska K1, Kublin E1, Mazurek AP1
Acta Poloniae Pharmaceutica, 01 Nov 2013, 70(6):951-959

Promethazine Sulfone is chemically 10-(2-(dimethylamino)propyl)-10H-phenothiazine 5,5-dioxide. It is also known as Dioxopromethazine. Promethazine Sulfone is supplied with detailed characterization data compliant with regulatory guideline. Promethazine Sulfone can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Promethazine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.