Cortisone 21-Hemisuccinate

N° de SZ CAT:	SZ-H008053
Número CAS	10215-75-5
Mol.F.	C25H32O8
Peso Molecular	460.5
Status de Fatura	In Stock
Rel. CAS No	7415-42-1 (Na salt)

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Nome Químico: 4-(2-((8S,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=C(COC(CCC(O)=O)=O)[C@](CC1)(O)[C@](C2)(C)[C@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O

Comparative study of two different chromatographic approaches for quantitation of hydrocortisone acetate and pramoxine hydrochloride in presence of their impurities
Fawzia Ibrahim a , Asmaa Kamal El-Deen a,b , Kuniyoshi Shimizu
Journal of Food and Drug Analysis Volume 26, Issue 3, July 2018, Pages 1160-1170

Novel stability indicating UHPLC method development and validation for simultaneous quantification of hydrocortisone acetate, pramoxine hydrochloride, potassium sorbate and sorbic acid in topical cream formulation
Lakshmi Narasimha RaoKatakamaThirupathiDongalabSanthosh KumarEttaboina
Talanta Open Volume 1, August 2020, 100004

Novel eco-friendly chromatographic determinations of hydrocortisone acetate, fusidic acid, their pharmacologically active impurities and pharmaceutical excipients: a comparative study
Maha M. Abdelrahman, Raghda Abdelmoneim Emam, Nouruddin W. Ali & Eglal A. Abdelaleem
Chemical Papers volume 74, pages2175–2187(2020)

An RP-HPLC Method for the Stability-Indicating Analysis of Impurities of Both Fusidic Acid and Betamethasone-17-Valerate in a Semi-Solid Pharmaceutical Dosage Form
Jonathan Byrne, Trinidad Velasco-Torrijos, Robert Reinhardt
Journal of Chromatographic Science, Volume 53, Issue 9, October 2015, Pages 1498–1503

Analytical method development and determination of hydrocortisone acetate and fusidic acid simultaneously in cream formulation, by reversed‐phase HPLC
Nawaz Rasool, Qudsia Kanwal, Muhammad Waseem
Biomedical Chromatography Volume35, Issue3 March 2021 e4997

Cortisone 21-Hemisuccinate is chemically 4-(2-((8S,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid. Cortisone 21-Hemisuccinate is supplied with detailed characterization data compliant with regulatory guideline. Cortisone 21-Hemisuccinate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hydrocortisone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Hydrocortisone

N° de SZ CAT:	: SZ-H008001
Número CAS	: 50-23-7
Mol.F.	: C21H30O5
Peso Molecular	: 362.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity A

N° de SZ CAT:	: SZ-H008002
Número CAS	: 50-24-8
Mol.F.	: C21H28O5
Peso Molecular	: 360.4
Status de Fatura	: In Stock

Hydrocortisone EP Impurity B

N° de SZ CAT:	: SZ-H008003
Número CAS	: 53-06-5
Mol.F.	: C21H28O5
Peso Molecular	: 360.4
Status de Fatura	: In Stock

Hydrocortisone EP Impurity C

N° de SZ CAT:	: SZ-H008004
Número CAS	: 50-03-3
Mol.F.	: C23H32O6
Peso Molecular	: 404.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity D

N° de SZ CAT:	: SZ-H008005
Número CAS	: 53-35-0
Mol.F.	: C21H30O6
Peso Molecular	: 378.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity E

N° de SZ CAT:	: SZ-H008006
Número CAS	: 600-99-7
Mol.F.	: C21H28O5
Peso Molecular	: 360.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity F

N° de SZ CAT:	: SZ-H008007
Número CAS	: 152-58-9
Mol.F.	: C21H30O4
Peso Molecular	: 346.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity G

N° de SZ CAT:	: SZ-H008008
Número CAS	: 14760-49-7
Mol.F.	: C21H28O5
Peso Molecular	: 360.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity H

N° de SZ CAT:	: SZ-H008009
Número CAS	: NA
Mol.F.	: C21H30O6
Peso Molecular	: 378.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity I

N° de SZ CAT:	: SZ-H008010
Número CAS	: 103795-84-2
Mol.F.	: C21H30O6
Peso Molecular	: 378.5
Status de Fatura	: Custom Synthesis

Hydrocortisone EP Impurity J

N° de SZ CAT:	: SZ-H008011
Número CAS	: 16463-74-4
Mol.F.	: C23H32O6
Peso Molecular	: 404.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity K

N° de SZ CAT:	: SZ-H008012
Número CAS	: 640-87-9
Mol.F.	: C23H32O5
Peso Molecular	: 388.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity L

N° de SZ CAT:	: SZ-H008013
Número CAS	: 641-77-0
Mol.F.	: C21H30O4
Peso Molecular	: 346.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity M

N° de SZ CAT:	: SZ-H008014
Número CAS	: 566-35-8
Mol.F.	: C21H30O5
Peso Molecular	: 362.5
Status de Fatura	: In Stock

Hydrocortisone EP Impurity N

N° de SZ CAT:	: SZ-H008015
Número CAS	: NA
Mol.F.	: C42H58O10
Peso Molecular	: 722.9
Status de Fatura	: In Stock

Hydrocortisone EP Impurity O

N° de SZ CAT:	: SZ-H008016
Número CAS	: 154032-37-8
Mol.F.	: C21H30O6
Peso Molecular	: 378.5
Status de Fatura	: Custom Synthesis

6-Alpha Methyl Hydrocortisone

N° de SZ CAT:	: SZ-H008017
Número CAS	: 1625-39-4
Mol.F.	: C22H32O5
Peso Molecular	: 376.5
Status de Fatura	: In Stock

Hydrocortisone 17-21 Orthoester

N° de SZ CAT:	: SZ-H008018
Número CAS	: 13609-63-7
Mol.F.	: C26H38O6
Peso Molecular	: 446.6
Status de Fatura	: Out of Stock

Hydrocortisone-21-Butyrate

N° de SZ CAT:	: SZ-H008019
Número CAS	: 6677-99-2
Mol.F.	: C25H36O6
Peso Molecular	: 432.6
Status de Fatura	: Out of Stock

6α-Hydroxy Cortisol

N° de SZ CAT:	: SZ-H008020
Número CAS	: 2242-98-0
Mol.F.	: C21H30O6
Peso Molecular	: 378.5
Status de Fatura	: In Stock

Hydrocortisone (9b,11b)-Epoxide

N° de SZ CAT:	: SZ-H008021
Número CAS	: 10072-97-6
Mol.F.	: C21H28O5
Peso Molecular	: 360.5
Status de Fatura	: In Stock

Cortisone Succinate Sodium Salt

N° de SZ CAT:	: SZ-H008022
Número CAS	: 7415-42-1
Mol.F.	: C25H31O8 : Na
Peso Molecular	: 459.5 : 23.0
Status de Fatura	: In Stock

Hydrocortisone Impurity A

N° de SZ CAT:	: SZ-H008023
Número CAS	: 103228-51-9
Mol.F.	: C25H33O8 : Na
Peso Molecular	: 461.5 : 23.0
Status de Fatura	: In Stock

Hydrocortisone Impurity B

N° de SZ CAT:	: SZ-H008024
Número CAS	: 105562-12-7
Mol.F.	: C21H28O4
Peso Molecular	: 344.5
Status de Fatura	: In Stock

Hydrocortisone Impurity C

N° de SZ CAT:	: SZ-H008025
Número CAS	: 105562-13-8
Mol.F.	: C21H28O4
Peso Molecular	: 344.5
Status de Fatura	: In Stock

Hydrocortisone Impurity D (Na)

N° de SZ CAT:	: SZ-H008026
Número CAS	: 70795-33-4
Mol.F.	: C25H33O7 : Na
Peso Molecular	: 445.5 : 23.0
Status de Fatura	: In Stock

Hydrocortisone 17-Succinate

N° de SZ CAT:	: SZ-H008027
Número CAS	: 220489-73-6
Mol.F.	: C25H34O8
Peso Molecular	: 462.5
Status de Fatura	: In Stock

Hydrocortisone Sodium Phosphate

N° de SZ CAT:	: SZ-H008028
Número CAS	: 6000-74-4
Mol.F.	: C21H29O8P2 : 2(Na)
Peso Molecular	: 440.4 : 2(23.0)
Status de Fatura	: In Stock

Hydrocortisone-21-Valerate

N° de SZ CAT:	: SZ-H008029
Número CAS	: 6678-00-8
Mol.F.	: C26H38O6
Peso Molecular	: 446.6
Status de Fatura	: Custom Synthesis

Prednisolone-21-Valerate

N° de SZ CAT:	: SZ-H008031
Número CAS	: 39791-31-6
Mol.F.	: C26H36O6
Peso Molecular	: 444.6
Status de Fatura	: In Stock

Hydrocortisone Acetate EP Impurity C

N° de SZ CAT:	: SZ-H008032
Número CAS	: 52-21-1
Mol.F.	: C23H30O6
Peso Molecular	: 402.5
Status de Fatura	: In Stock

Hydrocortisone Acetate EP Impurity D

N° de SZ CAT:	: SZ-H008033
Número CAS	: 50-04-4
Mol.F.	: C23H30O6
Peso Molecular	: 402.5
Status de Fatura	: In Stock

Hydrocortisone Acetate EP Impurity E

N° de SZ CAT:	: SZ-H008034
Número CAS	: 7753-60-8
Mol.F.	: C23H30O5
Peso Molecular	: 386.5
Status de Fatura	: In Stock

Hydrocortisone Acetate EP Impurity F

N° de SZ CAT:	: SZ-H008035
Número CAS	: 1250-97-1
Mol.F.	: C23H32O6
Peso Molecular	: 404.5
Status de Fatura	: In Stock

Hydrocortisone Acetate EP Impurity G

N° de SZ CAT:	: SZ-H008036
Número CAS	: 81968-66-3
Mol.F.	: C25H34O7
Peso Molecular	: 446.5
Status de Fatura	: In Stock

Hydrocortisone Glyoxal Hydrate Isomer 1

N° de SZ CAT:	: SZ-H008037
Número CAS	: 1960421-03-7
Mol.F.	: C21H30O5
Peso Molecular	: 362.5
Status de Fatura	: In Stock

Hydrocortisone Glyoxal Hydrate Isomer 2

N° de SZ CAT:	: SZ-H008038
Número CAS	: NA
Mol.F.	: C21H30O5
Peso Molecular	: 362.5
Status de Fatura	: Custom Synthesis

11-β-Hydroxyandrostenedione

N° de SZ CAT:	: SZ-H008039
Número CAS	: 382-44-5
Mol.F.	: C19H26O3
Peso Molecular	: 302.4
Status de Fatura	: In Stock

Hydrocortisone Oxo Acetic Acid

N° de SZ CAT:	: SZ-H008041
Número CAS	: 33762-00-4
Mol.F.	: C21H28O5
Peso Molecular	: 360.5
Status de Fatura	: In Stock

Hydrocortisone Impurity E

N° de SZ CAT:	: SZ-H008042
Número CAS	: NA
Mol.F.	: C25H39NO7
Peso Molecular	: 465.6
Status de Fatura	: Custom Synthesis

Hydrocortisone Impurity F

N° de SZ CAT:	: SZ-H008043
Número CAS	: NA
Mol.F.	: C22H32O5
Peso Molecular	: 376.5
Status de Fatura	: Out of Stock, Custom Synthesis

Hydrocortisone Impurity G

N° de SZ CAT:	: SZ-H008044
Número CAS	: NA
Mol.F.	: C21H30O5
Peso Molecular	: 362.5
Status de Fatura	: In Stock

Hydrocortisone Impurity H

N° de SZ CAT:	: SZ-H008045
Número CAS	: 2394-25-4
Mol.F.	: C20H28O4
Peso Molecular	: 332.4
Status de Fatura	: In Stock

Hydrocortisone D4

N° de SZ CAT:	: SZ-H008D01
Número CAS	: 73565-87-4
Mol.F.	: C21H26D4O5
Peso Molecular	: 366.5
Status de Fatura	: Custom Synthesis

Hydrocortisone Impurity 1

N° de SZ CAT:	: SZ-H008046
Número CAS	: NA
Mol.F.	: C29H44O7
Peso Molecular	: 504.7
Status de Fatura	: Custom Synthesis

Hydrocortisone Impurity 2

N° de SZ CAT:	: SZ-H008047
Número CAS	: NA
Mol.F.	: C29H44O7
Peso Molecular	: 504.7
Status de Fatura	: Custom Synthesis

Hydrocortisone Impurity 3

N° de SZ CAT:	: SZ-H008048
Número CAS	: NA
Mol.F.	: C10H18O5
Peso Molecular	: 218.2
Status de Fatura	: Custom Synthesis

Hydrocortisone Valerate Impurity 3

N° de SZ CAT:	: SZ-H008049
Número CAS	: NA
Mol.F.	: C26H36O7
Peso Molecular	: 460.6
Status de Fatura	: Custom Synthesis

9α-Bromohydrocortisone Acetate

N° de SZ CAT:	: SZ-H008050
Número CAS	: 50733-54-5
Mol.F.	: C23H31BrO6
Peso Molecular	: 483.4
Status de Fatura	: In Stock

Δ9(11)-Hydrocortisone 17-Valerate

N° de SZ CAT:	: SZ-H008051
Número CAS	: NA
Mol.F.	: C26H36O5
Peso Molecular	: 428.6
Status de Fatura	: In Stock

Hydrocortisone Un-Symmetrical Dimer

N° de SZ CAT:	: SZ-H008052
Número CAS	: NA
Mol.F.	: C42H58O9
Peso Molecular	: 706.9
Status de Fatura	: In Stock