Bosutinib Dimer Impurity 2

SZ CAT No:	SZ-B063020
CAS No	2095306-26-4
Mol.F.	C46H44Cl4N8O6
Mol.Wt.	946.7
Inv. Status	Custom Synthesis

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Chemical Name: 7,7'-((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=CC(Cl)=C(NC2=C(C#N)C=NC3=CC(OCCCN4CCN(CCCOC5=C(OC)C=C6C(N=CC(C#N)=C6NC7=C(Cl)C=C(Cl)C(OC)=C7)=C5)CC4)=C(OC)C=C23)C=C1OC

Method development and validation for related substances of Bosutinib monohydrate by RP-HPLC method
By Parmar, Yogendra B.; Shah, Dharmesh; Majmudar, Yashraj A.; Kaka, Ketul C.; Patel, Arpan S.; Kankad, Pankaj D.; Sartanpara, Uday G.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 838-854

RP-HPLC method for estimation of Bosutinib in bulk form as per ICH guidelines
By Chaudhari, Vidya L.; Kulkarni, Amol A.
From World Journal of Pharmaceutical Research (2016), 5(12), 417-424

Bosutinib Dimer Impurity 2 is chemically 7,7'-((Piperazine-1,4-diylbis(propane-3,1-diyl))bis(oxy))bis(4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile). Bosutinib Dimer Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Bosutinib Dimer Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bosutinib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-B063015
CAS No	: 98446-49-2
Mol.F.	: C7H7Cl2NO
Mol.Wt.	: 192.0
Inv. Status	: In Stock, 3-4 days for Dispatch
Rel. CAS No	: 379229-30-8 (HCl salt)

SZ CAT No:	: SZ-B063014
CAS No	: 636-93-1
Mol.F.	: C7H7NO4
Mol.Wt.	: 169.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 67233-85-6 (Na salt) ; 458534-58-2 (K salt)

SZ CAT No:	: SZ-B063001
CAS No	: 380843-75-4
Mol.F.	: C26H29Cl2N5O3
Mol.Wt.	: 530.5
Inv. Status	: In Stock
Rel. CAT No	: SZ-B063028 ,

SZ CAT No:	: SZ-B063028
CAS No	: 918639-08-4
Mol.F.	: C26H29Cl2N5O3 : H2O
Mol.Wt.	: 530.5 : 18.0
Inv. Status	: In Stock
Rel. CAS No	: 380843-75-4 (free base)
Rel. CAT No	: SZ-B063001 ,

Bosutinib Dimer Impurity 2

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SZ CAT No:	: SZ-B063009
CAS No	: 142072-71-7
Mol.F.	: C10H11NO4
Mol.Wt.	: 209.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063D01
CAS No	: 2733145-45-2
Mol.F.	: C26H21D8Cl2N5O3
Mol.Wt.	: 538.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063008
CAS No	: 2095306-25-3
Mol.F.	: C21H19Cl2N3O3
Mol.Wt.	: 432.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063003
CAS No	: 2468737-92-8
Mol.F.	: C25H27Cl2N5O3
Mol.Wt.	: 516.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063002
CAS No	: 2468737-94-0
Mol.F.	: C24H25Cl2N5O3
Mol.Wt.	: 502.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063005
CAS No	: NA
Mol.F.	: C47H46Cl4N8O6
Mol.Wt.	: 960.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063010
CAS No	: 219786-51-3
Mol.F.	: C10H12BrNO4
Mol.Wt.	: 290.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063011
CAS No	: 879644-03-8
Mol.F.	: C10H9ClN2O2
Mol.Wt.	: 224.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063012
CAS No	: 17722-32-6
Mol.F.	: C9H6Cl2N2O
Mol.Wt.	: 229.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063013
CAS No	: 1821033-10-6
Mol.F.	: C10H8Cl2N2O2
Mol.Wt.	: 259.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063016
CAS No	: 65182-98-1
Mol.F.	: C9H9Cl2NO2
Mol.Wt.	: 234.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063019
CAS No	: 1307530-78-4
Mol.F.	: C10H9ClN2O2
Mol.Wt.	: 224.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063020
CAS No	: 2095306-26-4
Mol.F.	: C46H44Cl4N8O6
Mol.Wt.	: 946.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063025
CAS No	: 380844-49-5
Mol.F.	: C21H18Cl3N3O3
Mol.Wt.	: 466.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063006
CAS No	: 846023-24-3
Mol.F.	: C10H8Cl2N2O2
Mol.Wt.	: 259.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063007
CAS No	: 846023-56-1
Mol.F.	: C26H31Cl2N5O4
Mol.Wt.	: 548.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063026
CAS No	: NA
Mol.F.	: C26H28Cl2N6O4
Mol.Wt.	: 559.4
Inv. Status	: Inquire

SZ CAT No:	: SZ-B063018
CAS No	: 2468737-96-2
Mol.F.	: C26H29Cl2N5O4
Mol.Wt.	: 546.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063017
CAS No	: NA
Mol.F.	: C26H30ClN5O4
Mol.Wt.	: 512.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063021
CAS No	: 2095306-27-5
Mol.F.	: C39H30Cl4N6O6
Mol.Wt.	: 820.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-B063027
CAS No	: 1391063-17-4
Mol.F.	: C26H29Cl2N5O3
Mol.Wt.	: 530.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063004
CAS No	: 380843-81-2
Mol.F.	: C25H27Cl2N5O3
Mol.Wt.	: 516.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-B063029
CAS No	: NA
Mol.F.	: C26H30Cl2N6O5
Mol.Wt.	: 577.5
Inv. Status	: Custom Synthesis