Metformin EP Impurity E (HCl salt)

SZ CAT No:	SZ-M018011
CAS No	1674-62-0
Mol.F.	C3H9N5 : HCl
Mol.Wt.	115.1 : 36.5
Inv. Status	In Stock
Rel. CAS No	1609-00-3 (free base) ; 36801-25-9 (Sulfate salt)
Shipping Condition	Ambient Temperature

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Chemical Name: 1-Methyl Biguanide hydrochloride (as per EP)

Synonym: Metformin USP Related Compound B ; N-Desmethyl Metformin

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: N=C(NC)NC(N)=N.Cl

Electrochemical and Computational Insights on the Application of Expired Metformin Drug as a Novel Inhibitor for the Sweet Corrosion of C1018 Steel
Ikenna B. Onyeachu, Safwat Abdel-Azeim, Dheeraj Singh Chauhan, and Mumtaz A. Quraishi
ACS Omega 2021, 6, 1, 65–76

Development and validation of a hydrophilic interaction liquid chromatography method for the quantitation of impurities in fixed-dose combination tablets containing rosuvastatin and metformin
George Machairas, Irene Panderi, Ariadni Geballa- Koukoula, Stavroula Rozou, Nikolaos Antonopoulos, Christos Charitos, Ariadni Vonaparti
Talanta Volume 183, 1 June 2018, Pages 131-141

Determination of impurities in medical products containing metformin hydrochloride
gabriela k£aczkow* and eløbieta l. anuszewska
Acta Poloniae Pharmaceutica ñ Drug Research, Vol. 67 No. 6 pp. 593-598, 2010

Retention Behavior of Metformin and Related Impurities in Ion-Pairing Liquid Chromatography
Victor David and Andrei Medvedovici, Florin Albu
Journal of Liquid Chromatography & Related Technologiesw, 28: 81–95, 2005

Development of normal phase high-performance liquid chromatographic method for determination of metformin and its related impurities in bulk material
Imad Osman Abu Reid
The Pharma Innovation Journal 2017; 6(5): 157-160

Metformin EP Impurity E (HCl salt) is chemically 1-Methyl Biguanide hydrochloride (as per EP) . It is also known as Metformin USP Related Compound B ; N-Desmethyl Metformin. Metformin EP Impurity E (HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. Metformin EP Impurity E (HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Metformin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-M018000
CAS No	: 1115-70-4
Mol.F.	: C4H11N5 : HCl
Mol.Wt.	: 129.2 : 36.5
Inv. Status	: In Stock
Rel. CAT No	: SZ-M018018 ,

SZ CAT No:	: SZ-M018018
CAS No	: 657-24-9
Mol.F.	: C4H11N5
Mol.Wt.	: 129.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1115-70-4 (HCl salt)
Rel. CAT No	: SZ-M018000 ,

Metformin EP Impurity E (HCl salt)

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SZ CAT No:	: SZ-M018001
CAS No	: 461-58-5
Mol.F.	: C2H4N4
Mol.Wt.	: 84.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018002
CAS No	: 2959-04-8
Mol.F.	: C4H8N8 : HCl
Mol.Wt.	: 168.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 4405-08-7 (free base) ; 3553-49-9 (nitrate Salt)

SZ CAT No:	: SZ-M018003
CAS No	: 1985-46-2
Mol.F.	: C5H10N6
Mol.Wt.	: 154.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018004
CAS No	: 108-78-1
Mol.F.	: C3H6N6
Mol.Wt.	: 126.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018005
CAS No	: 36801-25-9
Mol.F.	: C3H9N5 : H2SO4
Mol.Wt.	: 115.1 : 98.1
Inv. Status	: In Stock
Rel. CAS No	: 1609-00-3 (free base) ; 1674-62-0 (HCl salt)

SZ CAT No:	: SZ-M018D01
CAS No	: 1185166-01-1
Mol.F.	: C4H5D6N5
Mol.Wt.	: 135.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018010
CAS No	: 506-59-2
Mol.F.	: C2H7N : HCl
Mol.Wt.	: 45.09 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 124-40-3 (free base)

SZ CAT No:	: SZ-M018011
CAS No	: 1674-62-0
Mol.F.	: C3H9N5 : HCl
Mol.Wt.	: 115.1 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1609-00-3 (free base) ; 36801-25-9 (Sulfate salt)

SZ CAT No:	: SZ-M018012
CAS No	: 926-72-7
Mol.F.	: C2H6N4O : HCl
Mol.Wt.	: 102.1 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 141-83-3 (free base)

SZ CAT No:	: SZ-M018013
CAS No	: 98026-16-5
Mol.F.	: C4H10N4O
Mol.Wt.	: 130.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018014
CAS No	: 74-89-5
Mol.F.	: CH5N
Mol.Wt.	: 31.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-M018015
CAS No	: NA
Mol.F.	: C4H10N4O : HCl
Mol.Wt.	: 130.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 118632-64-7 (free base)

SZ CAT No:	: SZ-M018016
CAS No	: 7260-94-8
Mol.F.	: C3H7NO2
Mol.Wt.	: 89.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M018017
CAS No	: NA
Mol.F.	: C4H10N6O
Mol.Wt.	: 158.2
Inv. Status	: Inquire

SZ CAT No:	: SZ-M018020
CAS No	: 13452-82-9
Mol.F.	: C5H10N6
Mol.Wt.	: 154.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 58892-16-3 (HCl salt) ; 16274-39-8 (XHCl salt)

SZ CAT No:	: SZ-M018021
CAS No	: 4245-76-5
Mol.F.	: C2H6N4O2
Mol.Wt.	: 118.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M018022
CAS No	: NA
Mol.F.	: C2H3N5O
Mol.Wt.	: 113.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M018023
CAS No	: 58228-69-6
Mol.F.	: C4H7N5
Mol.Wt.	: 125.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-M018024
CAS No	: 847373-57-3
Mol.F.	: C4H7N5
Mol.Wt.	: 125.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P057070
CAS No	: 1312706-18-5
Mol.F.	: C15H17NO4
Mol.Wt.	: 275.3
Inv. Status	: Custom Synthesis

Metformin EP Impurity E (HCl salt)

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SZ CAT No:	: SZ-P057071
CAS No	: 1312706-19-6
Mol.F.	: C15H17NO4
Mol.Wt.	: 275.3
Inv. Status	: Custom Synthesis