Bisoprolol Impurity 15

N° de SZ CAT:	SZ-B003051
Número CAS	235097-76-4
Mol.F.	C6H14O4S
Peso Molecular	182.2
Status de Fatura	Custom Synthesis

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Nome Químico: 2-Isopropoxyethyl methanesulfonate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CS(OCCOC(C)C)(=O)=O

High-performance liquid chromatographic method for the determination of bisoprolol and potential impurities
Nelly N. Agapova*,Elissaveta Vasileva
Journal of Chromatogrkphy A, 654 (1993) 299-352

Investigation of the retention mechanisms of amlodipine besylate, bisoprolol fumarate, and their impurities on three different HILIC columns
Irena Kasagić-Vujanović, Biljana Jančić-Stojanović & Darko Ivanović
Journal of liquid chromatography & related technologies 2018, vol. 41, no. 9, 523–531

Robust UHPLC Separation Method Development for Multi‑API Product Containing Amlodipine and Bisoprolol: The Impact of Column Selection
Róbert Kormány, Imre Molnár, Jenő Fekete, Davy Guillarme & Szabolcs Fekete
Chromatographia volume 77, pages1119–1127(2014)

Stability-Indicating RP-HPLC and CE Methods for Simultaneous Determination of Bisoprolol and Perindopril in Pharmaceutical Formulation: A Comparative Study
Said A. Hassan, Nancy W. Nashat *, Mohamed R. Elghobashy, Samah S. Abbas and Azza A. Moustafa
Journal of Chromatographic Science, Volume 58, Issue 8, September 2020, Pages 747–758

Bisoprolol Impurity 15 is chemically 2-Isopropoxyethyl methanesulfonate. Bisoprolol Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Bisoprolol Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bisoprolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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2-Isopropoxyethanol

N° de SZ CAT:	: SZ-B003030
Número CAS	: 109-59-1
Mol.F.	: C5H12O2
Peso Molecular	: 104.2
Status de Fatura	: In Stock

4-Hydroxybenzaldehyde D5

N° de SZ CAT:	: SZ-B003D01
Número CAS	: 298704-22-0
Mol.F.	: C7HD5O2
Peso Molecular	: 127.2
Status de Fatura	: Custom Synthesis

Bisoprolol

N° de SZ CAT:	: SZ-B003047
Número CAS	: 66722-44-9
Mol.F.	: C18H31NO4
Peso Molecular	: 325.4
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 104344-23-2 (fumarate salt)
Rel. CAT No	: SZ-B003001 ,

Bisoprolol Alcohol Impurity

N° de SZ CAT:	: SZ-B003017
Número CAS	: 623-05-2
Mol.F.	: C7H8O2
Peso Molecular	: 124.1
Status de Fatura	: In Stock

Bisoprolol Benzylalcohol

N° de SZ CAT:	: SZ-B003046
Número CAS	: NA
Mol.F.	: C13H21NO3 : C4H4O4
Peso Molecular	: 239.3 : 116.1
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 2290571-50-3 (free base)

Bisoprolol Carboxylic Acid Impurity

N° de SZ CAT:	: SZ-B003020
Número CAS	: NA
Mol.F.	: C13H18LiNO4
Peso Molecular	: 259.2
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 72570-70-8 (free base)

Bisoprolol D5

N° de SZ CAT:	: SZ-B003D03
Número CAS	: NA
Mol.F.	: C18H26D5NO4
Peso Molecular	: 330.5
Status de Fatura	: Custom Synthesis

Bisoprolol D5 Fumarate

N° de SZ CAT:	: SZ-B003D02
Número CAS	: 2140803-85-4
Mol.F.	: C18H26D5NO4 : C4H4O4
Peso Molecular	: 330.5 : 116.1
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 1189881-87-5 (free base)

Bisoprolol Diene Impurity

N° de SZ CAT:	: SZ-B003035
Número CAS	: NA
Mol.F.	: C19H29NO2
Peso Molecular	: 303.4
Status de Fatura	: Custom Synthesis

Bisoprolol Dimer

N° de SZ CAT:	: SZ-B003023
Número CAS	: 2775292-22-1
Mol.F.	: C33H53NO8
Peso Molecular	: 591.8
Status de Fatura	: In Stock

Bisoprolol EP Impurity A

N° de SZ CAT:	: SZ-B003002
Número CAS	: 62572-93-4
Mol.F.	: C13H21NO3
Peso Molecular	: 239.3
Status de Fatura	: In Stock

Bisoprolol EP Impurity B

N° de SZ CAT:	: SZ-B003003
Número CAS	: 1447715-44-7
Mol.F.	: C18H31NO4
Peso Molecular	: 325.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity C

N° de SZ CAT:	: SZ-B003004
Número CAS	: 1797132-90-1
Mol.F.	: C25H38N2O4
Peso Molecular	: 430.6
Status de Fatura	: In Stock

Bisoprolol EP Impurity D

N° de SZ CAT:	: SZ-B003005
Número CAS	: 1225195-71-0
Mol.F.	: C26H40N205
Peso Molecular	: 460.6
Status de Fatura	: Out of Stock, Custom Synthesis
Rel. CAT No	: SZ-B003048 ,

Bisoprolol EP Impurity D (TFA)

N° de SZ CAT:	: SZ-B003048
Número CAS	: NA
Mol.F.	: C26H40N2O5 : 2(C2HF3O2)
Peso Molecular	: 460.6 : 2(114.0)
Status de Fatura	: Limited Stock
Rel. CAS No	: 1225195-71-0 (TFA salt)
Rel. CAT No	: SZ-B003005 ,

Bisoprolol EP Impurity E

N° de SZ CAT:	: SZ-B003006
Número CAS	: 1217245-60-7
Mol.F.	: C18H29NO3
Peso Molecular	: 307.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity F

N° de SZ CAT:	: SZ-B003007
Número CAS	: 1798418-82-2
Mol.F.	: C18H31NO4
Peso Molecular	: 325.4
Status de Fatura	: In Stock
Rel. CAS No	: 2470233-28-2 (Fumarate salt)

Bisoprolol EP Impurity G

N° de SZ CAT:	: SZ-B003008
Número CAS	: NA
Mol.F.	: C19H33NO5 : 1/2(C4H4O4)
Peso Molecular	: 355.5 : 1/2(116.1)
Status de Fatura	: In Stock
Rel. CAS No	: 1215342-36-1 (free base)

Bisoprolol EP Impurity J

N° de SZ CAT:	: SZ-B003009
Número CAS	: 1797024-50-0
Mol.F.	: C15H24O5
Peso Molecular	: 284.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity K

N° de SZ CAT:	: SZ-B003010
Número CAS	: 864544-37-6
Mol.F.	: C18H29NO5
Peso Molecular	: 339.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity L

N° de SZ CAT:	: SZ-B003011
Número CAS	: 29122-74-5
Mol.F.	: C13H19NO3
Peso Molecular	: 237.3
Status de Fatura	: In Stock
Rel. CAS No	: 1956321-87-1 (HCl salt) ; 1639933-77-9 (Oxalate sat)
Rel. CAT No	: SZ-M021007 ,

Bisoprolol EP Impurity M

N° de SZ CAT:	: SZ-B003012
Número CAS	: 177034-57-0
Mol.F.	: C12H18O3
Peso Molecular	: 210.3
Status de Fatura	: In Stock

Bisoprolol EP Impurity N

N° de SZ CAT:	: SZ-B003013
Número CAS	: 1346601-75-9
Mol.F.	: C17H29NO4
Peso Molecular	: 311.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity Q

N° de SZ CAT:	: SZ-B003014
Número CAS	: 1346604-00-9
Mol.F.	: C16H27NO4
Peso Molecular	: 297.4
Status de Fatura	: In Stock

Bisoprolol EP Impurity R

N° de SZ CAT:	: SZ-B003015
Número CAS	: 5790-46-5
Mol.F.	: C13H21NO2
Peso Molecular	: 223.3
Status de Fatura	: In Stock

Bisoprolol EP Impurity S

N° de SZ CAT:	: SZ-B003016
Número CAS	: 123-08-0
Mol.F.	: C7H6O2
Peso Molecular	: 122.1
Status de Fatura	: In Stock

Bisoprolol EP Impurity T

N° de SZ CAT:	: SZ-B003024
Número CAS	: 1173203-26-3
Mol.F.	: C14H17NO4
Peso Molecular	: 263.3
Status de Fatura	: In Stock

Bisoprolol EP Impurity U

N° de SZ CAT:	: SZ-B003025
Número CAS	: 1071765-44-0
Mol.F.	: C14H19NO4
Peso Molecular	: 265.3
Status de Fatura	: In Stock

Bisoprolol Epoxide Impurity

N° de SZ CAT:	: SZ-B003018
Número CAS	: 66722-57-4
Mol.F.	: C15H22O4
Peso Molecular	: 266.3
Status de Fatura	: In Stock

Bisoprolol Fumarate

N° de SZ CAT:	: SZ-B003001
Número CAS	: 104344-23-2
Mol.F.	: C18H31NO4 : 1/2(C4H4O4)
Peso Molecular	: 325.4 : 1/2(116.1)
Status de Fatura	: In Stock
Rel. CAS No	: 66722-44-9 (free base)
Rel. CAT No	: SZ-B003047 ,

Bisoprolol Hydroxyethyl Ester Impurity

N° de SZ CAT:	: SZ-B003034
Número CAS	: 1346601-19-1
Mol.F.	: C15H23NO5
Peso Molecular	: 297.4
Status de Fatura	: In Stock

Bisoprolol Hydroxymethyl Oxiran Impurity

N° de SZ CAT:	: SZ-B003019
Número CAS	: 4204-78-8
Mol.F.	: C10H12O3
Peso Molecular	: 180.2
Status de Fatura	: In Stock