Apixaban Impurity 27

N° de SZ CAT:	SZ-A062038
Número CAS	2133292-60-9
Mol.F.	C26H27ClN4O5
Peso Molecular	511.0
Status de Fatura	Out of Stock, Custom Synthesis

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Nome Químico: Methyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=C1C2=C(C(C(OC)=O)=NN2C3=CC=C(OC)C=C3)CCN1C4=CC=C(NC(CCCCCl)=O)C=C4

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1

Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123

Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785

Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1 · Nathalie Ribeiro Wingert1 · Nadia Maria Volpato1 · Cássia Virginia Garcia1 · Elfrides E. S. Schapoval1 · Martin Steppe
Chromatographia volume 83, pages65–75(2020)

Apixaban Impurity 27 is chemically Methyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate. Apixaban Impurity 27 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 27 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Apixaban

N° de SZ CAT:	: SZ-A062001
Número CAS	: 503612-47-3
Mol.F.	: C25H25N5O4
Peso Molecular	: 459.5
Status de Fatura	: In Stock

Apixaban 13C D3

N° de SZ CAT:	: SZ-A062D01
Número CAS	: 1261393-15-0
Mol.F.	: C2413CH22D3N5O4
Peso Molecular	: 463.5
Status de Fatura	: Custom Synthesis

Apixaban Amino Acid Impurity

N° de SZ CAT:	: SZ-A062012
Número CAS	: 2206825-87-6
Mol.F.	: C25H27N5O5
Peso Molecular	: 477.5
Status de Fatura	: In Stock

Apixaban Amino Acid Impurity Hydrochloride

N° de SZ CAT:	: SZ-A062089
Número CAS	: 2241139-69-3
Mol.F.	: C25H27N5O5 : HCl
Peso Molecular	: 477.5 : 36.5
Status de Fatura	: In Stock

Apixaban Dimer Impurity

N° de SZ CAT:	: SZ-A062053
Número CAS	: 1998079-11-0
Mol.F.	: C40H34N10O6
Peso Molecular	: 750.8
Status de Fatura	: Custom Synthesis

Apixaban Ethoxy Impurity

N° de SZ CAT:	: SZ-A062077
Número CAS	: 37522-29-5
Mol.F.	: C12H15ClN2O3
Peso Molecular	: 270.7
Status de Fatura	: In Stock

Apixaban Ethyl Ester Dimer Impurity

N° de SZ CAT:	: SZ-A062096
Número CAS	: NA
Mol.F.	: C36H32N6O8
Peso Molecular	: 676.7
Status de Fatura	: Custom Synthesis

Apixaban USP Related Compound D

N° de SZ CAT:	: SZ-A062021
Número CAS	: 1351611-14-7
Mol.F.	: C26H25N5O5
Peso Molecular	: 487.5
Status de Fatura	: In Stock

Apixaban Impurity 11

N° de SZ CAT:	: SZ-A062022
Número CAS	: 2204368-51-2
Mol.F.	: C29H31N5O5
Peso Molecular	: 529.6
Status de Fatura	: Custom Synthesis

Apixaban Impurity 13

N° de SZ CAT:	: SZ-A062090
Número CAS	: 2206825-81-0
Mol.F.	: C25H27N5O5
Peso Molecular	: 477.5
Status de Fatura	: Out of Stock

Apixaban Impurity 14

N° de SZ CAT:	: SZ-A062025
Número CAS	: 1704504-93-7
Mol.F.	: C20H18N4O4
Peso Molecular	: 378.4
Status de Fatura	: In Stock

Apixaban Impurity 15

N° de SZ CAT:	: SZ-A062026
Número CAS	: 1466571-07-2
Mol.F.	: C21H20N4O4
Peso Molecular	: 392.4
Status de Fatura	: In Stock

Apixaban Impurity 16

N° de SZ CAT:	: SZ-A062027
Número CAS	: 2203740-09-2
Mol.F.	: C26H29N5O5
Peso Molecular	: 491.5
Status de Fatura	: In Stock

Apixaban Impurity 17

N° de SZ CAT:	: SZ-A062028
Número CAS	: 1423803-24-0
Mol.F.	: C20H19N5O3
Peso Molecular	: 377.4
Status de Fatura	: Limited Stock

Apixaban Impurity 18

N° de SZ CAT:	: SZ-A062029
Número CAS	: 1643330-62-4
Mol.F.	: C20H26ClN3O3
Peso Molecular	: 391.9
Status de Fatura	: In Stock

Apixaban Impurity 19

N° de SZ CAT:	: SZ-A062030
Número CAS	: 503615-07-4
Mol.F.	: C22H22N4O4
Peso Molecular	: 406.4
Status de Fatura	: In Stock

Apixaban Open Ring Amide (USP)

N° de SZ CAT:	: SZ-A062013
Número CAS	: 2187409-01-2
Mol.F.	: C25H28N6O4
Peso Molecular	: 476.5
Status de Fatura	: In Stock

Apixaban USP Related Compound H

N° de SZ CAT:	: SZ-A062031
Número CAS	: 1421823-20-2
Mol.F.	: C27H29ClN4O5
Peso Molecular	: 525.0
Status de Fatura	: In Stock

Apixaban Impurity 22

N° de SZ CAT:	: SZ-A062033
Número CAS	: 405872-78-8
Mol.F.	: C11H13ClN2O3
Peso Molecular	: 256.7
Status de Fatura	: Custom Synthesis

Apixaban Impurity 23

N° de SZ CAT:	: SZ-A062034
Número CAS	: 1801881-17-3
Mol.F.	: C24H23N5O3
Peso Molecular	: 429.5
Status de Fatura	: In Stock

Apixaban Impurity 24

N° de SZ CAT:	: SZ-A062035
Número CAS	: 1928718-22-2
Mol.F.	: C26H27N5O4
Peso Molecular	: 473.5
Status de Fatura	: In Stock

Apixaban Impurity 26

N° de SZ CAT:	: SZ-A062037
Número CAS	: 1449510-64-8
Mol.F.	: C25H26ClN5O4
Peso Molecular	: 496.0
Status de Fatura	: In Stock