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Levothyroxine Related Products


SynZeal is a leading innovator in pharmaceutical reference standards. We supply high-quality Reference Standards of Levothyroxine, pharmacopeial and non-pharmacopeial Levothyroxine impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Levothyroxine impurities reference standards are useful in pharmaceutical research. They are useful in product development, ANDA and DMF filing, quality control (QC), method validation, and stability studies. It is also useful in the identification of unknown impurities and the assessment of genotoxic potential.

Levothyroxine-related products are thoroughly characterized. Levothyroxine products are supplied with detailed COA & analytical data meeting regulatory compliance. We can also provide EP/USP traceable standards based on your requirements. The supplied products are re-tested at regular intervals.

Pharmaceutical Reference Standards

3,5-Dibromo-L-tyrosine

Picture of 3,5-Dibromo-L-tyrosine
SZ CAT No:: SZ-L022042
CAS No: 300-38-9
Mol.F.: C9H9Br2NO3
Mol.Wt.: 339.0
Inv. Status: In Stock

3,5-Dichloro-L-Tyrosine

Picture of 3,5-Dichloro-L-Tyrosine
SZ CAT No:: SZ-L022041
CAS No: 15106-62-4
Mol.F.: C9H9Cl2NO3
Mol.Wt.: 250.1
Inv. Status: In Stock

Levothyroxine

Picture of Levothyroxine
SZ CAT No:: SZ-L022032
CAS No: 51-48-9
Mol.F.: C15H11I4NO4
Mol.Wt.: 776.9
Inv. Status: In Stock
Rel. CAS No: 55-03-8 (Na salt)

Levothyroxine EP Impurity H 

Picture of Levothyroxine EP Impurity H 
SZ CAT No:: SZ-L022008
CAS No: 2055-97-2
Mol.F.: C13H6I4O4
Mol.Wt.: 733.8
Inv. Status: In Stock

Levothyroxine N-Acetyl Impurity

Picture of Levothyroxine N-Acetyl Impurity
SZ CAT No:: SZ-L022017
CAS No: 26041-51-0
Mol.F.: C17H13I4NO5
Mol.Wt.: 818.9
Inv. Status: In Stock

Levothyroxine N-Formyl Impurity

Picture of Levothyroxine N-Formyl Impurity
SZ CAT No:: SZ-L022015
CAS No: 671235-41-9
Mol.F.: C16H11I4NO5
Mol.Wt.: 804.9
Inv. Status: In Stock

Levothyroxine Sodium Hydrate

Picture of Levothyroxine Sodium Hydrate
SZ CAT No:: SZ-L022012
CAS No: 25416-65-3
Mol.F.: C15H10I4NO4 : Na : x(H2O)
Mol.Wt.: 775.9 : 23.0 : x(18.0)
Inv. Status: In Stock
Rel. CAS No: 51-48-9 (free base) : 55-03-8 (Na salt)

Levothyroxine T4-Hydroxyacetic Acid

Picture of Levothyroxine T4-Hydroxyacetic Acid
SZ CAT No:: SZ-L022014
CAS No: 93647-48-4
Mol.F.: C14H8I4O5
Mol.Wt.: 763.8
Inv. Status: In Stock

Levothyroxine  Impurity 1

Picture of Levothyroxine  Impurity 1
SZ CAT No:: SZ-L022028
CAS No: 2055-94-9
Mol.F.: C13H8I4O3
Mol.Wt.: 719.8
Inv. Status: In Stock

Levothyroxine  Impurity 12

Picture of Levothyroxine  Impurity 12
SZ CAT No:: SZ-L022053
CAS No: 889871-36-7
Mol.F.: C9H9ClINO3
Mol.Wt.: 341.5
Inv. Status: In Stock

Levothyroxine  Impurity 3

Picture of Levothyroxine  Impurity 3
SZ CAT No:: SZ-L022030
CAS No: 854646-83-6
Mol.F.: C8H7I2NO3
Mol.Wt.: 419.0
Inv. Status: In Stock

Levothyroxine  Impurity 5

Picture of Levothyroxine  Impurity 5
SZ CAT No:: SZ-L022033
CAS No: 51-26-3
Mol.F.: C15H11I3O4
Mol.Wt.: 636.0
Inv. Status: In Stock

Levothyroxine EP Impurity A

Picture of Levothyroxine EP Impurity A
SZ CAT No:: SZ-L022002
CAS No: 55-06-1
Mol.F.: C15H11I3NO4 : Na
Mol.Wt.: 650.0 : 23.0
Inv. Status: In Stock
Rel. CAS No: 6893-02-3 (free base)
Rel. CAT No: SZ-L077011 , SZ-L077001 ,

Levothyroxine EP Impurity D

Picture of Levothyroxine EP Impurity D
SZ CAT No:: SZ-L022005
CAS No: 67-30-1
Mol.F.: C14H8I4O4
Mol.Wt.: 747.8
Inv. Status: In Stock
Rel. CAT No: SZ-L077005 ,

Levothyroxine EP Impurity E

Picture of Levothyroxine EP Impurity E
SZ CAT No:: SZ-L022006
CAS No: 1041-01-6
Mol.F.: C15H13I2NO4
Mol.Wt.: 525.1
Inv. Status: In Stock
Rel. CAT No: SZ-L077006 ,

Levothyroxine EP Impurity F

Picture of Levothyroxine EP Impurity F
SZ CAT No:: SZ-L022007
CAS No: 911661-90-0
Mol.F.: C21H13I6NO5
Mol.Wt.: 1120.8
Inv. Status: In Stock

Levothyroxine Ethyl Ester

Picture of Levothyroxine Ethyl Ester
SZ CAT No:: SZ-L022020
CAS No: 76353-71-4
Mol.F.: C17H15I4NO4
Mol.Wt.: 804.9
Inv. Status: In Stock

Levothyroxine Methoxyphenoxy Aldehyde Impurity

Picture of Levothyroxine Methoxyphenoxy Aldehyde Impurity
SZ CAT No:: SZ-L022019
CAS No: 69240-57-9
Mol.F.: C14H10I2O3
Mol.Wt.: 480.0
Inv. Status: In Stock

Levothyroxine N-Methylamide (USP)

Picture of Levothyroxine N-Methylamide (USP)
SZ CAT No:: SZ-L022023
CAS No: 2088032-52-2
Mol.F.: C16H14I4N2O3
Mol.Wt.: 789.9
Inv. Status: In Stock

Levothyroxine O-Methyl Amine Impurity

Picture of Levothyroxine O-Methyl Amine Impurity
SZ CAT No:: SZ-L022025
CAS No: 2230724-39-5
Mol.F.: C15H13I4NO2
Mol.Wt.: 746.9
Inv. Status: In Stock

Levothyroxine Sodium Pentahydrate

Picture of Levothyroxine Sodium Pentahydrate
SZ CAT No:: SZ-L022001
CAS No: 25416-65-3
Mol.F.: C15H10I4NO4 : Na : 5(H2O)
Mol.Wt.: 798.9 : 23.0 : 5(18.0)
Inv. Status: In Stock
Rel. CAS No: 51-48-9 (free base) ; 55-03-8 (Na salt)

Liothyronine Maillard Lactose Impurity

Picture of Liothyronine Maillard Lactose Impurity
SZ CAT No:: SZ-L022039
CAS No: NA
Mol.F.: C27H32I3NO14
Mol.Wt.: 975.3
Inv. Status: In Stock

N-Acetyl L-Thyroxine Ethyl Ester

Picture of N-Acetyl L-Thyroxine Ethyl Ester
SZ CAT No:: SZ-L022037
CAS No: 30804-52-5
Mol.F.: C19H17I4NO5
Mol.Wt.: 847.0
Inv. Status: In Stock

T4-Acetamide

Picture of T4-Acetamide
SZ CAT No:: SZ-L022016
CAS No: 176258-88-1
Mol.F.: C14H9I4NO3
Mol.Wt.: 746.8
Inv. Status: In Stock

T4-Formic acid N-methylamide

Picture of T4-Formic acid N-methylamide
SZ CAT No:: SZ-L022035
CAS No: 2088032-78-2
Mol.F.: C14H9I4NO3
Mol.Wt.: 746.8
Inv. Status: In Stock

Thyroxamine Hydrochloride

Picture of Thyroxamine Hydrochloride
SZ CAT No:: SZ-L022048
CAS No: 788824-71-5
Mol.F.: C14H11I4NO2 : HCl
Mol.Wt.: 732.9 : 36.5
Inv. Status: In Stock
Rel. CAS No: 3571-49-1 (free base) ; 1628689-42-8 (TFA salt)

Levothyroxine EP Impurity I

Picture of Levothyroxine EP Impurity I
SZ CAT No:: SZ-L022009
CAS No: 2016-06-0
Mol.F.: C13H6I4O3
Mol.Wt.: 717.8
Inv. Status: Limited Stock

Levothyroxine EP Impurity J

Picture of Levothyroxine EP Impurity J
SZ CAT No:: SZ-L022010
CAS No: 4604-41-5
Mol.F.: C15H13I2NO4
Mol.Wt.: 525.1
Inv. Status: Limited Stock

Levothyroxine EP Impurity C

Picture of Levothyroxine EP Impurity C
SZ CAT No:: SZ-L022004
CAS No: 51-24-1
Mol.F.: C14H9I3O4
Mol.Wt.: 621.9
Inv. Status: Limited Stock
Rel. CAT No: SZ-L077004 ,

Levothyroxine Monochloro Impurity

Picture of Levothyroxine Monochloro Impurity
SZ CAT No:: SZ-L022022
CAS No: 909279-46-5
Mol.F.: C15H11ClI3NO4
Mol.Wt.: 685.4
Inv. Status: Limited Stock

3,5,3',5'-Tetraiodo Thyrolactic Acid

Picture of 3,5,3',5'-Tetraiodo Thyrolactic Acid
SZ CAT No:: SZ-L022026
CAS No: 7069-47-8
Mol.F.: C15H10I4O5
Mol.Wt.: 777.9
Inv. Status: Out of Stock, Custom Synthesis

Levothyroxine EP Impurity K

Picture of Levothyroxine EP Impurity K
SZ CAT No:: SZ-L022011
CAS No: 5817-39-0
Mol.F.: C15H12I3NO4
Mol.Wt.: 650.9
Inv. Status: Out of Stock, Custom Synthesis

Levothyroxine Glucose Adduct

Picture of Levothyroxine Glucose Adduct
SZ CAT No:: SZ-L022034
CAS No: NA
Mol.F.: C21H21I4NO9
Mol.Wt.: 939.0
Inv. Status: Out of Stock

3,3’,5-Triiodo-D-thyronine

Picture of 3,3’,5-Triiodo-D-thyronine
SZ CAT No:: SZ-L022056
CAS No: 5714-08-9
Mol.F.: C15H12I3NO4
Mol.Wt.: 651.0
Inv. Status: Custom Synthesis

3,5-Diiodo Thyroacetic Acid

Picture of 3,5-Diiodo Thyroacetic Acid
SZ CAT No:: SZ-L022060
CAS No: 1155-40-4
Mol.F.: C14H10I2O4
Mol.Wt.: 496.0
Inv. Status: Custom Synthesis
Rel. CAS No: 1155-41-5 (sodium salt)

3-Bromo-L-Thyroxine

Picture of 3-Bromo-L-Thyroxine
SZ CAT No:: SZ-L022038
CAS No: 1798894-90-2
Mol.F.: C15H11BrI3NO4
Mol.Wt.: 729.9
Inv. Status: Custom Synthesis

3-Monoiodothyronine

Picture of 3-Monoiodothyronine
SZ CAT No:: SZ-L022049
CAS No: 16170-92-6
Mol.F.: C15H14INO4
Mol.Wt.: 399.2
Inv. Status: Custom Synthesis

Levothyroxine Impurity 15

Picture of Levothyroxine Impurity 15
SZ CAT No:: SZ-L022057
CAS No: NA
Mol.F.: C27H31I4NO14
Mol.Wt.: 1101.2
Inv. Status: Custom Synthesis

Levothyroxine Impurity 18

Picture of Levothyroxine Impurity 18
SZ CAT No:: SZ-L022063
CAS No: NA
Mol.F.: C33H45I4NO5
Mol.Wt.: 1043.3
Inv. Status: Custom Synthesis

Levothyroxine Impurity 19

Picture of Levothyroxine Impurity 19
SZ CAT No:: SZ-L022064
CAS No: NA
Mol.F.: C30H31I4NO5
Mol.Wt.: 993.2
Inv. Status: Custom Synthesis

Levothyroxine Impurity 20

Picture of Levothyroxine Impurity 20
SZ CAT No:: SZ-L022065
CAS No: NA
Mol.F.: C17H13I4NO4
Mol.Wt.: 802.9
Inv. Status: Custom Synthesis

Levothyroxine Lactose Adduct

Picture of Levothyroxine Lactose Adduct
SZ CAT No:: SZ-L022045
CAS No: NA
Mol.F.: C27H32I3NO14
Mol.Wt.: 975.3
Inv. Status: Custom Synthesis

Levothyroxine Mannitol Adduct

Picture of Levothyroxine Mannitol Adduct
SZ CAT No:: SZ-L022040
CAS No: NA
Mol.F.: C21H23I4NO9
Mol.Wt.: 941.0
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 10

Picture of Levothyroxine  Impurity 10
SZ CAT No:: SZ-L022050
CAS No: NA
Mol.F.: C16H11I4NO5
Mol.Wt.: 804.9
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 11

Picture of Levothyroxine  Impurity 11
SZ CAT No:: SZ-L022052
CAS No: 2244907-74-0
Mol.F.: C13H12IO2 : CF3O3S
Mol.Wt.: 327.1 : 149.1
Inv. Status: Custom Synthesis
Rel. CAS No: 167998-35-8 (free base)

Levothyroxine  Impurity 13

Picture of Levothyroxine  Impurity 13
SZ CAT No:: SZ-L022054
CAS No: 77667-01-7
Mol.F.: C15H11BrI3NO4
Mol.Wt.: 729.9
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 16

Picture of Levothyroxine  Impurity 16
SZ CAT No:: SZ-L022059
CAS No: 92905-78-7
Mol.F.: C14H10I3NO3
Mol.Wt.: 621.0
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 2

Picture of Levothyroxine  Impurity 2
SZ CAT No:: SZ-L022029
CAS No: 176258-89-2
Mol.F.: C14H10I4O2
Mol.Wt.: 717.9
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 4

Picture of Levothyroxine  Impurity 4
SZ CAT No:: SZ-L022031
CAS No: NA
Mol.F.: C16H12I4NO4 : Na
Mol.Wt.: 789.9 : 23.0
Inv. Status: Custom Synthesis
Rel. CAS No: 4367-89-9 (free base)

Levothyroxine  Impurity 9

Picture of Levothyroxine  Impurity 9
SZ CAT No:: SZ-L022047
CAS No: 3861-58-3
Mol.F.: C7H4INO4
Mol.Wt.: 293.0
Inv. Status: Custom Synthesis

Levothyroxine D-Isomer

Picture of Levothyroxine D-Isomer
SZ CAT No:: SZ-L022024
CAS No: 51-49-0
Mol.F.: C15H11I4NO4
Mol.Wt.: 776.9
Inv. Status: Custom Synthesis

Levothyroxine EP Impurity B

Picture of Levothyroxine EP Impurity B
SZ CAT No:: SZ-L022003
CAS No: 1628720-66-0
Mol.F.: C15H11ClI3NO4
Mol.Wt.: 685.4
Inv. Status: Custom Synthesis

Levothyroxine Hydroxyphenoxy Aldehyde Impurity

Picture of Levothyroxine Hydroxyphenoxy Aldehyde Impurity
SZ CAT No:: SZ-L022018
CAS No: 2828-49-1
Mol.F.: C13H8I2O3
Mol.Wt.: 466.0
Inv. Status: Custom Synthesis

Levothyroxine Impurity 17

Picture of Levothyroxine Impurity 17
SZ CAT No:: SZ-L022062
CAS No: NA
Mol.F.: C33H45I4NO5
Mol.Wt.: 1043.3
Inv. Status: Custom Synthesis

Levothyroxine Impurity 6

Picture of Levothyroxine Impurity 6
SZ CAT No:: SZ-L022036
CAS No: 105172-64-3
Mol.F.: C15H11I3N2O6
Mol.Wt.: 696.0
Inv. Status: Custom Synthesis

Levothyroxine Methyl Ester

Picture of Levothyroxine Methyl Ester
SZ CAT No:: SZ-L022021
CAS No: 32180-11-3
Mol.F.: C16H13I4NO4
Mol.Wt.: 790.9
Inv. Status: Custom Synthesis

Levothyroxine Sodium

Picture of Levothyroxine Sodium
SZ CAT No:: SZ-L022044
CAS No: 55-03-8
Mol.F.: C15H10I4NO4 : Na
Mol.Wt.: 775.9 : 23.0
Inv. Status: Custom Synthesis
Rel. CAS No: 51-48-9 (free base) ; 6106-07-6 (sodium pentahydrate)

L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)

Picture of L-Tyrosine,3,5-diiodo-o-(4-Methoxyphenyl)
SZ CAT No:: SZ-L022027
CAS No: 94345-95-6
Mol.F.: C16H15I2NO4
Mol.Wt.: 539.1
Inv. Status: Custom Synthesis
Rel. CAT No: SZ-L077010 ,

N-Formyl-T4 and T4-Acetamide

Picture of N-Formyl-T4 and T4-Acetamide
SZ CAT No:: SZ-L022058
CAS No: NA
Mol.F.: C16H11I4NO5 : C14H9I4NO3
Mol.Wt.: 804.9 : 746.8
Inv. Status: Custom Synthesis

O-(4-Hydroxy-3-iodophenyl) Levothyroxine

Picture of O-(4-Hydroxy-3-iodophenyl) Levothyroxine
SZ CAT No:: SZ-L022061
CAS No: 2086274-34-0
Mol.F.: C21H14I5NO5
Mol.Wt.: 994.9
Inv. Status: Custom Synthesis

Thyroxine Glucuronide

Picture of Thyroxine Glucuronide
SZ CAT No:: SZ-L022066
CAS No: 21462-56-6
Mol.F.: C21H19I4NO10
Mol.Wt.: 953.0
Inv. Status: Custom Synthesis

Thyroxine Sodium

Picture of Thyroxine Sodium
SZ CAT No:: SZ-L022051
CAS No: NA
Mol.F.: C15H11I4NO4 : Na
Mol.Wt.: 776.9 : 23.0
Inv. Status: Custom Synthesis
Rel. CAS No: 300-30-1 (free base)

β-Hydroxy Thyroxine

Picture of β-Hydroxy Thyroxine
SZ CAT No:: SZ-L022043
CAS No: 107849-54-7
Mol.F.: C15H11I4NO5
Mol.Wt.: 792.9
Inv. Status: Custom Synthesis

Levothyroxine  Impurity 14

Picture of Levothyroxine  Impurity 14
SZ CAT No:: SZ-L022055
CAS No: 2088032-62-4
Mol.F.: C30H21I7N2O8
Mol.Wt.: 1425.8
Inv. Status: Under Synthesis

Digallic Acid

Picture of Digallic Acid
SZ CAT No:: SZ-L022068
CAS No: 536-08-3
Mol.F.: C14H10O9
Mol.Wt.: 322.2
Inv. Status:

Levothroxine Gallic Acid Adduct

Picture of Levothroxine Gallic Acid Adduct
SZ CAT No:: SZ-L022067
CAS No: NA
Mol.F.: C22H15I4NO8
Mol.Wt.: 929.0
Inv. Status:

Stable Isotopes And Metabolites

Levothyroxine 13C9 15N

Picture of Levothyroxine 13C9 15N
SZ CAT No:: SZ-L022D02
CAS No: 1431868-11-9
Mol.F.: C613C9H11I415NO4
Mol.Wt.: 786.8
Inv. Status: Custom Synthesis

Levothyroxine D3

Picture of Levothyroxine D3
SZ CAT No:: SZ-L022D01
CAS No: NA
Mol.F.: C15H8D3I4NO4
Mol.Wt.: 779.9
Inv. Status: Custom Synthesis

Thyroxine-13C6

Picture of Thyroxine-13C6
SZ CAT No:: SZ-L022D03
CAS No: 1217780-14-7
Mol.F.: C913C6H11I4NO4
Mol.Wt.: 782.8
Inv. Status: Custom Synthesis
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