Chemical Name: (17Beta-(2,2-Dihydroxyacetyl)-11Beta-hydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-androsta-1,4-dien-3-one) (as per USP)
Synonym: Desonide-21-aldehyde hydrate
Smiles: O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H]5[C@]4(OC(C)(C)O5)C(C(O)O)=O)=C1.O=C6C=C[C@@]7(C)C(CC[C@]8([H])[C@]7([H])[C@@H](O)C[C@@]9(C)[C@@]8([H])C[C@@H]%10[C@]9(OC(C)(C)O%10)C(C=O)=O)=C6
Inchi: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
Development of a novel HPLC method for the determination of the impurities in desonide cream and characterization of its impurities by 2D LC-IT-TOF MS
Jian Wanga,b, Shuxian Zhenga, Yu Xua, Haiyan Huc, Minji Shenc, Lan Tang
Journal of Pharmaceutical and Biomedical Analysis 161 (2018) 399–406
Studies on the Stability of Corticosteroids: Degradation of Clobetasol Propionate, Desonide and Hydrocortisone in Topical Formulations by HPLC and UPLC-MS/MS
Kishore Kumar Hotha, Subathra Ramamoorthy1, Hiren Patel
American Journal of Analytical Chemistry, 2020, 11, 147-171