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Acetylcysteine EP Impurity B

SZ CAT No SZ-A016016
CAS No 52-90-4
Mol.F. C3H7NO2S
Mol.Wt. 121.2
Inv. Status Custom Synthesis
Rel. CAS No 44521-10-0 (Na salt) ; 52-89-1 (HCl salt) ; 659719-78-5 (K salt) ; 82650-08-6 (HBr salt)


Chemical Name: (2R)-2-amino-3-sulfanylpropanoic acid (as per EP)

Synonym: L-Cysteine

Capillary electrophoretic separation of N-acetylcysteine and its impurities as a method for quality control of pharmaceuticals
M. Jaworska , G. Szulinska, M. Wilk, J. Tautt
Journal of Chromatography A, 853 (1999) 479–485
 
Mechanism of Scavenging Action of N-Acetylcysteine for the OH Radical: A Quantum Computational Study
Neha Agnihotri and P. C. Mishra
J. Phys. Chem. B 2009, 113, 12096–12104
 
High-Throughput UPLC–MS Method for the Determination of N-Acetyl-L-Cysteine: Application in Tissue Distribution Study in Wistar Rats
Masoom Raza Siddiqui, Saikh Mohammad Wabaidur, Mohammad Shamsul Ola, Zeid A. AlOthman, Mohammad Zulfiqar Ali Rafiquee, Moonis Ali Khan
Journal of Chromatographic Science, Volume 54, Issue 7, 1 August 2016, Pages 1244–1252
 
Development and Validation of RP-HPLC Method for the Estimation of NAcetylcysteine in Wet Cough Syrup
Shaikh Sanaa , Dr. Athawale Rajania*, Dr. Nadkar Sumedhab , Phadtare Pravinb and Dr. Naik Shripad
Int. J. Drug Dev. & Res., April-June 2012, 4 (2): 284-293